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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and Investar Holding Corp (ISTR). Click either name above to swap in a different company.

Investar Holding Corp is the larger business by last-quarter revenue ($23.5M vs $18.7M, roughly 1.3× CytomX Therapeutics, Inc.). On growth, Investar Holding Corp posted the faster year-over-year revenue change (0.9% vs -25.7%). Over the past eight quarters, Investar Holding Corp's revenue compounded faster (4.9% CAGR vs -15.9%).

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

Investar Holding Corp is a U.S.-headquartered bank holding company that primarily operates across the Gulf Coast region. It delivers a full range of commercial and retail banking services, including deposit products, consumer and business loans, mortgage services, and wealth management solutions for individual clients, small and medium-sized enterprises, and commercial entities.

CTMX vs ISTR — Head-to-Head

Bigger by revenue
ISTR
ISTR
1.3× larger
ISTR
$23.5M
$18.7M
CTMX
Growing faster (revenue YoY)
ISTR
ISTR
+26.6% gap
ISTR
0.9%
-25.7%
CTMX
Faster 2-yr revenue CAGR
ISTR
ISTR
Annualised
ISTR
4.9%
-15.9%
CTMX

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
ISTR
ISTR
Revenue
$18.7M
$23.5M
Net Profit
$-154.0K
Gross Margin
Operating Margin
-6.9%
30.9%
Net Margin
-0.8%
Revenue YoY
-25.7%
0.9%
Net Profit YoY
97.6%
EPS (diluted)
$0.50

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
ISTR
ISTR
Q4 25
$23.5M
Q3 25
$24.1M
Q2 25
$18.7M
$22.3M
Q1 25
$50.9M
$24.0M
Q4 24
$38.1M
$23.3M
Q3 24
$33.4M
$22.3M
Q2 24
$25.1M
$20.4M
Q1 24
$41.5M
$21.4M
Net Profit
CTMX
CTMX
ISTR
ISTR
Q4 25
Q3 25
$6.2M
Q2 25
$-154.0K
$4.5M
Q1 25
$23.5M
$6.3M
Q4 24
$18.9M
Q3 24
$5.7M
$5.4M
Q2 24
$-6.5M
$4.1M
Q1 24
$13.8M
$4.7M
Operating Margin
CTMX
CTMX
ISTR
ISTR
Q4 25
30.9%
Q3 25
31.0%
Q2 25
-6.9%
24.4%
Q1 25
44.4%
32.2%
Q4 24
46.4%
31.1%
Q3 24
12.3%
27.6%
Q2 24
-33.7%
24.0%
Q1 24
28.1%
28.5%
Net Margin
CTMX
CTMX
ISTR
ISTR
Q4 25
Q3 25
25.6%
Q2 25
-0.8%
20.2%
Q1 25
46.2%
26.3%
Q4 24
49.6%
Q3 24
17.2%
24.1%
Q2 24
-26.0%
19.9%
Q1 24
33.3%
22.0%
EPS (diluted)
CTMX
CTMX
ISTR
ISTR
Q4 25
$0.50
Q3 25
$0.54
Q2 25
$0.46
Q1 25
$0.63
Q4 24
$0.61
Q3 24
$0.54
Q2 24
$0.41
Q1 24
$0.48

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
ISTR
ISTR
Cash + ST InvestmentsLiquidity on hand
$49.0M
Total DebtLower is stronger
$9.8M
Stockholders' EquityBook value
$119.9M
$301.1M
Total Assets
$175.1M
$2.8B
Debt / EquityLower = less leverage
0.03×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
ISTR
ISTR
Q4 25
Q3 25
Q2 25
$49.0M
Q1 25
$47.6M
Q4 24
$38.1M
Q3 24
$40.6M
Q2 24
$43.2M
Q1 24
$36.2M
Total Debt
CTMX
CTMX
ISTR
ISTR
Q4 25
$9.8M
Q3 25
Q2 25
Q1 25
Q4 24
$9.8M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
CTMX
CTMX
ISTR
ISTR
Q4 25
$301.1M
Q3 25
$295.3M
Q2 25
$119.9M
$255.9M
Q1 25
$25.0M
$251.7M
Q4 24
$-456.0K
$241.3M
Q3 24
$-23.5M
$245.5M
Q2 24
$-31.2M
$230.2M
Q1 24
$-31.7M
$227.0M
Total Assets
CTMX
CTMX
ISTR
ISTR
Q4 25
$2.8B
Q3 25
$2.8B
Q2 25
$175.1M
$2.7B
Q1 25
$98.5M
$2.7B
Q4 24
$120.5M
$2.7B
Q3 24
$139.0M
$2.8B
Q2 24
$159.2M
$2.8B
Q1 24
$184.7M
$2.8B
Debt / Equity
CTMX
CTMX
ISTR
ISTR
Q4 25
0.03×
Q3 25
Q2 25
Q1 25
Q4 24
0.04×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
ISTR
ISTR
Operating Cash FlowLast quarter
$-15.8M
$18.2M
Free Cash FlowOCF − Capex
$-15.8M
FCF MarginFCF / Revenue
-84.6%
Capex IntensityCapex / Revenue
0.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-77.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
ISTR
ISTR
Q4 25
$18.2M
Q3 25
$6.9M
Q2 25
$-15.8M
$3.2M
Q1 25
$-21.0M
$4.5M
Q4 24
$-19.9M
$15.9M
Q3 24
$-20.7M
$5.6M
Q2 24
$-19.5M
$2.8M
Q1 24
$-26.0M
$7.8M
Free Cash Flow
CTMX
CTMX
ISTR
ISTR
Q4 25
Q3 25
Q2 25
$-15.8M
Q1 25
$-21.2M
Q4 24
$-20.0M
Q3 24
$-20.7M
Q2 24
$-19.6M
Q1 24
$-26.2M
FCF Margin
CTMX
CTMX
ISTR
ISTR
Q4 25
Q3 25
Q2 25
-84.6%
Q1 25
-41.6%
Q4 24
-52.5%
Q3 24
-62.1%
Q2 24
-78.2%
Q1 24
-63.1%
Capex Intensity
CTMX
CTMX
ISTR
ISTR
Q4 25
Q3 25
Q2 25
0.1%
Q1 25
0.2%
Q4 24
0.2%
Q3 24
0.1%
Q2 24
0.4%
Q1 24
0.3%
Cash Conversion
CTMX
CTMX
ISTR
ISTR
Q4 25
Q3 25
1.12×
Q2 25
0.71×
Q1 25
-0.89×
0.71×
Q4 24
-1.05×
Q3 24
-3.61×
1.03×
Q2 24
0.70×
Q1 24
-1.89×
1.66×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

ISTR
ISTR

Segment breakdown not available.

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