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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and SOUTHERN FIRST BANCSHARES INC (SFST). Click either name above to swap in a different company.

SOUTHERN FIRST BANCSHARES INC is the larger business by last-quarter revenue ($31.8M vs $18.7M, roughly 1.7× CytomX Therapeutics, Inc.). On growth, SOUTHERN FIRST BANCSHARES INC posted the faster year-over-year revenue change (26.1% vs -25.7%). SOUTHERN FIRST BANCSHARES INC produced more free cash flow last quarter ($29.9M vs $-15.8M). Over the past eight quarters, SOUTHERN FIRST BANCSHARES INC's revenue compounded faster (22.2% CAGR vs -15.9%).

CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.

First Community Bankshares, Inc. is a $2.43 billion bank holding company and the parent company of First Community Bank of Bluefield, Virginia, in the United States. As of 2012 First Community Bank had 45 locations in Virginia, West Virginia, and North Carolina, and two locations operating as Peoples Community Bank in Tennessee. As of April 21, 2023, First Community had $3.6 billion in assets.

CTMX vs SFST — Head-to-Head

Bigger by revenue
SFST
SFST
1.7× larger
SFST
$31.8M
$18.7M
CTMX
Growing faster (revenue YoY)
SFST
SFST
+51.8% gap
SFST
26.1%
-25.7%
CTMX
More free cash flow
SFST
SFST
$45.7M more FCF
SFST
$29.9M
$-15.8M
CTMX
Faster 2-yr revenue CAGR
SFST
SFST
Annualised
SFST
22.2%
-15.9%
CTMX

Income Statement — Q2 FY2025 vs Q4 FY2025

Metric
CTMX
CTMX
SFST
SFST
Revenue
$18.7M
$31.8M
Net Profit
$-154.0K
Gross Margin
Operating Margin
-6.9%
40.1%
Net Margin
-0.8%
Revenue YoY
-25.7%
26.1%
Net Profit YoY
97.6%
EPS (diluted)
$1.19

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CTMX
CTMX
SFST
SFST
Q4 25
$31.8M
Q3 25
$31.1M
Q2 25
$18.7M
$28.6M
Q1 25
$50.9M
$26.5M
Q4 24
$38.1M
$25.2M
Q3 24
$33.4M
$23.8M
Q2 24
$25.1M
$23.1M
Q1 24
$41.5M
$21.3M
Net Profit
CTMX
CTMX
SFST
SFST
Q4 25
Q3 25
$8.7M
Q2 25
$-154.0K
$6.6M
Q1 25
$23.5M
$5.3M
Q4 24
$18.9M
Q3 24
$5.7M
$4.4M
Q2 24
$-6.5M
$3.0M
Q1 24
$13.8M
$2.5M
Operating Margin
CTMX
CTMX
SFST
SFST
Q4 25
40.1%
Q3 25
36.4%
Q2 25
-6.9%
30.0%
Q1 25
44.4%
26.1%
Q4 24
46.4%
27.3%
Q3 24
12.3%
24.1%
Q2 24
-33.7%
17.0%
Q1 24
28.1%
15.9%
Net Margin
CTMX
CTMX
SFST
SFST
Q4 25
Q3 25
27.8%
Q2 25
-0.8%
23.0%
Q1 25
46.2%
19.9%
Q4 24
49.6%
Q3 24
17.2%
18.4%
Q2 24
-26.0%
13.0%
Q1 24
33.3%
11.8%
EPS (diluted)
CTMX
CTMX
SFST
SFST
Q4 25
$1.19
Q3 25
$1.07
Q2 25
$0.81
Q1 25
$0.65
Q4 24
$0.69
Q3 24
$0.54
Q2 24
$0.37
Q1 24
$0.31

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CTMX
CTMX
SFST
SFST
Cash + ST InvestmentsLiquidity on hand
$49.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$119.9M
$368.7M
Total Assets
$175.1M
$4.4B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CTMX
CTMX
SFST
SFST
Q4 25
Q3 25
Q2 25
$49.0M
Q1 25
$47.6M
Q4 24
$38.1M
Q3 24
$40.6M
Q2 24
$43.2M
Q1 24
$36.2M
Stockholders' Equity
CTMX
CTMX
SFST
SFST
Q4 25
$368.7M
Q3 25
$356.3M
Q2 25
$119.9M
$345.5M
Q1 25
$25.0M
$337.6M
Q4 24
$-456.0K
$330.4M
Q3 24
$-23.5M
$326.5M
Q2 24
$-31.2M
$318.7M
Q1 24
$-31.7M
$315.3M
Total Assets
CTMX
CTMX
SFST
SFST
Q4 25
$4.4B
Q3 25
$4.4B
Q2 25
$175.1M
$4.3B
Q1 25
$98.5M
$4.3B
Q4 24
$120.5M
$4.1B
Q3 24
$139.0M
$4.2B
Q2 24
$159.2M
$4.1B
Q1 24
$184.7M
$4.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CTMX
CTMX
SFST
SFST
Operating Cash FlowLast quarter
$-15.8M
$30.5M
Free Cash FlowOCF − Capex
$-15.8M
$29.9M
FCF MarginFCF / Revenue
-84.6%
93.8%
Capex IntensityCapex / Revenue
0.1%
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-77.7M
$62.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CTMX
CTMX
SFST
SFST
Q4 25
$30.5M
Q3 25
$14.5M
Q2 25
$-15.8M
$10.5M
Q1 25
$-21.0M
$7.6M
Q4 24
$-19.9M
$25.6M
Q3 24
$-20.7M
$26.3M
Q2 24
$-19.5M
$4.0M
Q1 24
$-26.0M
$-2.9M
Free Cash Flow
CTMX
CTMX
SFST
SFST
Q4 25
$29.9M
Q3 25
$14.4M
Q2 25
$-15.8M
$10.4M
Q1 25
$-21.2M
$7.4M
Q4 24
$-20.0M
$24.8M
Q3 24
$-20.7M
$26.1M
Q2 24
$-19.6M
$3.9M
Q1 24
$-26.2M
$-3.2M
FCF Margin
CTMX
CTMX
SFST
SFST
Q4 25
93.8%
Q3 25
46.3%
Q2 25
-84.6%
36.3%
Q1 25
-41.6%
28.1%
Q4 24
-52.5%
98.2%
Q3 24
-62.1%
110.0%
Q2 24
-78.2%
16.8%
Q1 24
-63.1%
-15.0%
Capex Intensity
CTMX
CTMX
SFST
SFST
Q4 25
1.8%
Q3 25
0.3%
Q2 25
0.1%
0.3%
Q1 25
0.2%
0.5%
Q4 24
0.2%
3.1%
Q3 24
0.1%
0.8%
Q2 24
0.4%
0.4%
Q1 24
0.3%
1.3%
Cash Conversion
CTMX
CTMX
SFST
SFST
Q4 25
Q3 25
1.67×
Q2 25
1.59×
Q1 25
-0.89×
1.44×
Q4 24
-1.05×
Q3 24
-3.61×
6.01×
Q2 24
1.32×
Q1 24
-1.89×
-1.16×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

CTMX
CTMX

Bristol Myers Squibb Company$11.6M62%
Astellas Pharma Inc$4.6M25%
Regeneron Pharmaceuticals Inc$2.1M11%

SFST
SFST

Segment breakdown not available.

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