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Side-by-side financial comparison of CytomX Therapeutics, Inc. (CTMX) and Usio, Inc. (USIO). Click either name above to swap in a different company.
Usio, Inc. is the larger business by last-quarter revenue ($22.2M vs $18.7M, roughly 1.2× CytomX Therapeutics, Inc.). CytomX Therapeutics, Inc. runs the higher net margin — -0.8% vs -6.7%, a 5.9% gap on every dollar of revenue. On growth, Usio, Inc. posted the faster year-over-year revenue change (8.2% vs -25.7%). Usio, Inc. produced more free cash flow last quarter ($1.1M vs $-15.8M). Over the past eight quarters, Usio, Inc.'s revenue compounded faster (3.0% CAGR vs -15.9%).
CytomX Therapeutics is a clinical-stage biotechnology company specializing in innovative cancer immunotherapies. It leverages its proprietary Probody technology platform to develop targeted therapies that activate exclusively in tumor microenvironments, minimizing off-target toxicities, with a pipeline covering multiple solid tumor indications and partnerships with leading global pharmaceutical firms.
Usio, Inc. is an American financial technology company headquartered in San Antonio, Texas. It provides integrated electronic payment services, including ACH processing, credit card and debit card acceptance, payment facilitation for software platforms, prepaid card issuing and a document print and mail operation.
CTMX vs USIO — Head-to-Head
Income Statement — Q2 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $18.7M | $22.2M |
| Net Profit | $-154.0K | $-1.5M |
| Gross Margin | — | 21.9% |
| Operating Margin | -6.9% | -5.7% |
| Net Margin | -0.8% | -6.7% |
| Revenue YoY | -25.7% | 8.2% |
| Net Profit YoY | 97.6% | -337.8% |
| EPS (diluted) | — | $-0.05 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | — | $22.2M | ||
| Q3 25 | — | $21.2M | ||
| Q2 25 | $18.7M | $20.0M | ||
| Q1 25 | $50.9M | $22.0M | ||
| Q4 24 | $38.1M | $20.6M | ||
| Q3 24 | $33.4M | $21.3M | ||
| Q2 24 | $25.1M | $20.1M | ||
| Q1 24 | $41.5M | $21.0M |
| Q4 25 | — | $-1.5M | ||
| Q3 25 | — | $-415.1K | ||
| Q2 25 | $-154.0K | $-366.7K | ||
| Q1 25 | $23.5M | $-235.0K | ||
| Q4 24 | $18.9M | $628.9K | ||
| Q3 24 | $5.7M | $2.9M | ||
| Q2 24 | $-6.5M | $75.5K | ||
| Q1 24 | $13.8M | $-250.2K |
| Q4 25 | — | 21.9% | ||
| Q3 25 | — | 23.0% | ||
| Q2 25 | — | 25.8% | ||
| Q1 25 | — | 21.9% | ||
| Q4 24 | — | 24.6% | ||
| Q3 24 | — | 23.0% | ||
| Q2 24 | — | 23.9% | ||
| Q1 24 | — | 23.1% |
| Q4 25 | — | -5.7% | ||
| Q3 25 | — | -2.2% | ||
| Q2 25 | -6.9% | -2.0% | ||
| Q1 25 | 44.4% | -1.1% | ||
| Q4 24 | 46.4% | -2.9% | ||
| Q3 24 | 12.3% | -1.8% | ||
| Q2 24 | -33.7% | -1.0% | ||
| Q1 24 | 28.1% | -1.3% |
| Q4 25 | — | -6.7% | ||
| Q3 25 | — | -2.0% | ||
| Q2 25 | -0.8% | -1.8% | ||
| Q1 25 | 46.2% | -1.1% | ||
| Q4 24 | 49.6% | 3.1% | ||
| Q3 24 | 17.2% | 13.4% | ||
| Q2 24 | -26.0% | 0.4% | ||
| Q1 24 | 33.3% | -1.2% |
| Q4 25 | — | $-0.05 | ||
| Q3 25 | — | $-0.02 | ||
| Q2 25 | — | $-0.01 | ||
| Q1 25 | — | $-0.01 | ||
| Q4 24 | — | $0.03 | ||
| Q3 24 | — | $0.10 | ||
| Q2 24 | — | $0.00 | ||
| Q1 24 | — | $-0.01 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $49.0M | $7.4M |
| Total DebtLower is stronger | — | $1.4M |
| Stockholders' EquityBook value | $119.9M | $17.9M |
| Total Assets | $175.1M | $134.9M |
| Debt / EquityLower = less leverage | — | 0.08× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $7.4M | ||
| Q3 25 | — | $7.7M | ||
| Q2 25 | $49.0M | $8.1M | ||
| Q1 25 | $47.6M | $8.7M | ||
| Q4 24 | $38.1M | $8.1M | ||
| Q3 24 | $40.6M | $8.4M | ||
| Q2 24 | $43.2M | $7.2M | ||
| Q1 24 | $36.2M | $7.1M |
| Q4 25 | — | $1.4M | ||
| Q3 25 | — | $836.7K | ||
| Q2 25 | — | $647.1K | ||
| Q1 25 | — | $683.3K | ||
| Q4 24 | — | $719.4K | ||
| Q3 24 | — | $562.9K | ||
| Q2 24 | — | $597.2K | ||
| Q1 24 | — | $630.9K |
| Q4 25 | — | $17.9M | ||
| Q3 25 | — | $18.7M | ||
| Q2 25 | $119.9M | $18.7M | ||
| Q1 25 | $25.0M | $19.0M | ||
| Q4 24 | $-456.0K | $19.2M | ||
| Q3 24 | $-23.5M | $18.9M | ||
| Q2 24 | $-31.2M | $15.7M | ||
| Q1 24 | $-31.7M | $15.3M |
| Q4 25 | — | $134.9M | ||
| Q3 25 | — | $99.4M | ||
| Q2 25 | $175.1M | $108.4M | ||
| Q1 25 | $98.5M | $109.6M | ||
| Q4 24 | $120.5M | $107.2M | ||
| Q3 24 | $139.0M | $114.6M | ||
| Q2 24 | $159.2M | $108.8M | ||
| Q1 24 | $184.7M | $99.1M |
| Q4 25 | — | 0.08× | ||
| Q3 25 | — | 0.04× | ||
| Q2 25 | — | 0.03× | ||
| Q1 25 | — | 0.04× | ||
| Q4 24 | — | 0.04× | ||
| Q3 24 | — | 0.03× | ||
| Q2 24 | — | 0.04× | ||
| Q1 24 | — | 0.04× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-15.8M | $1.5M |
| Free Cash FlowOCF − Capex | $-15.8M | $1.1M |
| FCF MarginFCF / Revenue | -84.6% | 4.8% |
| Capex IntensityCapex / Revenue | 0.1% | 2.0% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $-77.7M | $1.7M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | — | $1.5M | ||
| Q3 25 | — | $303.8K | ||
| Q2 25 | $-15.8M | $-263.9K | ||
| Q1 25 | $-21.0M | $1.4M | ||
| Q4 24 | $-19.9M | $2.9M | ||
| Q3 24 | $-20.7M | $1.4M | ||
| Q2 24 | $-19.5M | $369.1K | ||
| Q1 24 | $-26.0M | $88.7K |
| Q4 25 | — | $1.1M | ||
| Q3 25 | — | $85.2K | ||
| Q2 25 | $-15.8M | $-503.2K | ||
| Q1 25 | $-21.2M | $1.1M | ||
| Q4 24 | $-20.0M | $2.7M | ||
| Q3 24 | $-20.7M | $1.4M | ||
| Q2 24 | $-19.6M | $246.3K | ||
| Q1 24 | $-26.2M | $-88.1K |
| Q4 25 | — | 4.8% | ||
| Q3 25 | — | 0.4% | ||
| Q2 25 | -84.6% | -2.5% | ||
| Q1 25 | -41.6% | 4.8% | ||
| Q4 24 | -52.5% | 13.1% | ||
| Q3 24 | -62.1% | 6.4% | ||
| Q2 24 | -78.2% | 1.2% | ||
| Q1 24 | -63.1% | -0.4% |
| Q4 25 | — | 2.0% | ||
| Q3 25 | — | 1.0% | ||
| Q2 25 | 0.1% | 1.2% | ||
| Q1 25 | 0.2% | 1.4% | ||
| Q4 24 | 0.2% | 1.0% | ||
| Q3 24 | 0.1% | 0.3% | ||
| Q2 24 | 0.4% | 0.6% | ||
| Q1 24 | 0.3% | 0.8% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | -0.89× | — | ||
| Q4 24 | -1.05× | 4.61× | ||
| Q3 24 | -3.61× | 0.50× | ||
| Q2 24 | — | 4.89× | ||
| Q1 24 | -1.89× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
CTMX
| Bristol Myers Squibb Company | $11.6M | 62% |
| Astellas Pharma Inc | $4.6M | 25% |
| Regeneron Pharmaceuticals Inc | $2.1M | 11% |
USIO
| Credit Card Revenue | $7.7M | 35% |
| ACH And Complementary Service Revenue | $6.1M | 28% |
| Output Solutions | $5.4M | 24% |
| Prepaid Card Services Revenue | $2.6M | 12% |
