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Side-by-side financial comparison of Cryoport, Inc. (CYRX) and SOUTHERN FIRST BANCSHARES INC (SFST). Click either name above to swap in a different company.

Cryoport, Inc. is the larger business by last-quarter revenue ($45.5M vs $31.8M, roughly 1.4× SOUTHERN FIRST BANCSHARES INC). On growth, SOUTHERN FIRST BANCSHARES INC posted the faster year-over-year revenue change (26.1% vs 9.6%). SOUTHERN FIRST BANCSHARES INC produced more free cash flow last quarter ($29.9M vs $-4.5M). Over the past eight quarters, SOUTHERN FIRST BANCSHARES INC's revenue compounded faster (22.2% CAGR vs 10.4%).

Cryoport, Inc. is a global provider of specialized temperature-controlled logistics and supply chain solutions focused on the life sciences, biopharmaceutical, and cell and gene therapy sectors. It partners with research institutions, biotech firms, and pharmaceutical manufacturers globally to support the safe transport of sensitive biological materials including clinical trial samples and advanced therapy products.

First Community Bankshares, Inc. is a $2.43 billion bank holding company and the parent company of First Community Bank of Bluefield, Virginia, in the United States. As of 2012 First Community Bank had 45 locations in Virginia, West Virginia, and North Carolina, and two locations operating as Peoples Community Bank in Tennessee. As of April 21, 2023, First Community had $3.6 billion in assets.

CYRX vs SFST — Head-to-Head

Bigger by revenue
CYRX
CYRX
1.4× larger
CYRX
$45.5M
$31.8M
SFST
Growing faster (revenue YoY)
SFST
SFST
+16.5% gap
SFST
26.1%
9.6%
CYRX
More free cash flow
SFST
SFST
$34.4M more FCF
SFST
$29.9M
$-4.5M
CYRX
Faster 2-yr revenue CAGR
SFST
SFST
Annualised
SFST
22.2%
10.4%
CYRX

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
CYRX
CYRX
SFST
SFST
Revenue
$45.5M
$31.8M
Net Profit
$-8.0M
Gross Margin
47.8%
Operating Margin
-17.0%
40.1%
Net Margin
-17.5%
Revenue YoY
9.6%
26.1%
Net Profit YoY
57.4%
EPS (diluted)
$-0.19
$1.19

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
CYRX
CYRX
SFST
SFST
Q4 25
$45.5M
$31.8M
Q3 25
$44.2M
$31.1M
Q2 25
$45.5M
$28.6M
Q1 25
$41.0M
$26.5M
Q4 24
$41.5M
$25.2M
Q3 24
$38.3M
$23.8M
Q2 24
$39.7M
$23.1M
Q1 24
$37.3M
$21.3M
Net Profit
CYRX
CYRX
SFST
SFST
Q4 25
$-8.0M
Q3 25
$-6.9M
$8.7M
Q2 25
$105.2M
$6.6M
Q1 25
$-12.0M
$5.3M
Q4 24
$-18.7M
Q3 24
$805.0K
$4.4M
Q2 24
$-78.0M
$3.0M
Q1 24
$-18.9M
$2.5M
Gross Margin
CYRX
CYRX
SFST
SFST
Q4 25
47.8%
Q3 25
48.2%
Q2 25
47.0%
Q1 25
45.4%
Q4 24
47.0%
Q3 24
45.5%
Q2 24
44.5%
Q1 24
40.4%
Operating Margin
CYRX
CYRX
SFST
SFST
Q4 25
-17.0%
40.1%
Q3 25
-22.5%
36.4%
Q2 25
-21.2%
30.0%
Q1 25
-23.1%
26.1%
Q4 24
-30.7%
27.3%
Q3 24
-34.9%
24.1%
Q2 24
-196.5%
17.0%
Q1 24
-46.9%
15.9%
Net Margin
CYRX
CYRX
SFST
SFST
Q4 25
-17.5%
Q3 25
-15.7%
27.8%
Q2 25
231.4%
23.0%
Q1 25
-29.2%
19.9%
Q4 24
-45.1%
Q3 24
2.1%
18.4%
Q2 24
-196.4%
13.0%
Q1 24
-50.7%
11.8%
EPS (diluted)
CYRX
CYRX
SFST
SFST
Q4 25
$-0.19
$1.19
Q3 25
$-0.18
$1.07
Q2 25
$2.05
$0.81
Q1 25
$-0.28
$0.65
Q4 24
$-0.42
$0.69
Q3 24
$-0.02
$0.54
Q2 24
$-1.62
$0.37
Q1 24
$-0.43
$0.31

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
CYRX
CYRX
SFST
SFST
Cash + ST InvestmentsLiquidity on hand
$411.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$502.6M
$368.7M
Total Assets
$765.0M
$4.4B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
CYRX
CYRX
SFST
SFST
Q4 25
$411.2M
Q3 25
$421.3M
Q2 25
$426.0M
Q1 25
$244.0M
Q4 24
$250.6M
Q3 24
$259.4M
Q2 24
$414.9M
Q1 24
$438.2M
Stockholders' Equity
CYRX
CYRX
SFST
SFST
Q4 25
$502.6M
$368.7M
Q3 25
$513.3M
$356.3M
Q2 25
$519.1M
$345.5M
Q1 25
$398.8M
$337.6M
Q4 24
$401.9M
$330.4M
Q3 24
$418.6M
$326.5M
Q2 24
$400.1M
$318.7M
Q1 24
$472.2M
$315.3M
Total Assets
CYRX
CYRX
SFST
SFST
Q4 25
$765.0M
$4.4B
Q3 25
$774.3M
$4.4B
Q2 25
$773.9M
$4.3B
Q1 25
$699.8M
$4.3B
Q4 24
$703.5M
$4.1B
Q3 24
$701.8M
$4.2B
Q2 24
$852.3M
$4.1B
Q1 24
$942.8M
$4.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
CYRX
CYRX
SFST
SFST
Operating Cash FlowLast quarter
$919.0K
$30.5M
Free Cash FlowOCF − Capex
$-4.5M
$29.9M
FCF MarginFCF / Revenue
-10.0%
93.8%
Capex IntensityCapex / Revenue
12.0%
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-25.0M
$62.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
CYRX
CYRX
SFST
SFST
Q4 25
$919.0K
$30.5M
Q3 25
$2.2M
$14.5M
Q2 25
$-7.3M
$10.5M
Q1 25
$-4.3M
$7.6M
Q4 24
$-5.5M
$25.6M
Q3 24
$447.0K
$26.3M
Q2 24
$-8.0M
$4.0M
Q1 24
$-3.3M
$-2.9M
Free Cash Flow
CYRX
CYRX
SFST
SFST
Q4 25
$-4.5M
$29.9M
Q3 25
$-1.3M
$14.4M
Q2 25
$-11.7M
$10.4M
Q1 25
$-7.5M
$7.4M
Q4 24
$-10.7M
$24.8M
Q3 24
$-3.8M
$26.1M
Q2 24
$-11.8M
$3.9M
Q1 24
$-7.3M
$-3.2M
FCF Margin
CYRX
CYRX
SFST
SFST
Q4 25
-10.0%
93.8%
Q3 25
-2.9%
46.3%
Q2 25
-25.7%
36.3%
Q1 25
-18.3%
28.1%
Q4 24
-25.8%
98.2%
Q3 24
-9.9%
110.0%
Q2 24
-29.8%
16.8%
Q1 24
-19.5%
-15.0%
Capex Intensity
CYRX
CYRX
SFST
SFST
Q4 25
12.0%
1.8%
Q3 25
7.8%
0.3%
Q2 25
9.6%
0.3%
Q1 25
7.7%
0.5%
Q4 24
12.6%
3.1%
Q3 24
11.1%
0.8%
Q2 24
9.5%
0.4%
Q1 24
10.7%
1.3%
Cash Conversion
CYRX
CYRX
SFST
SFST
Q4 25
Q3 25
1.67×
Q2 25
-0.07×
1.59×
Q1 25
1.44×
Q4 24
Q3 24
0.56×
6.01×
Q2 24
1.32×
Q1 24
-1.16×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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