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Side-by-side financial comparison of DULUTH HOLDINGS INC. (DLTH) and IONIS PHARMACEUTICALS INC (IONS). Click either name above to swap in a different company.

IONIS PHARMACEUTICALS INC is the larger business by last-quarter revenue ($203.3M vs $114.9M, roughly 1.8× DULUTH HOLDINGS INC.). DULUTH HOLDINGS INC. runs the higher net margin — -8.8% vs -112.8%, a 104.0% gap on every dollar of revenue. On growth, DULUTH HOLDINGS INC. posted the faster year-over-year revenue change (-9.6% vs -10.3%). DULUTH HOLDINGS INC. produced more free cash flow last quarter ($-8.9M vs $-159.0M). Over the past eight quarters, IONIS PHARMACEUTICALS INC's revenue compounded faster (30.4% CAGR vs -31.6%).

Duluth Holdings Inc., which primarily sells goods through its Duluth Trading Company brand, is an American workwear and accessories company.

Ionis Pharmaceuticals, Inc. is a biotechnology company that specializes in discovering and developing antisense therapy, as well as RNA interference and CRISPR therapeutics. The company was founded in 1989 is based in Carlsbad, California. The company was previously known as Isis Pharmaceuticals until December 2015.

DLTH vs IONS — Head-to-Head

Bigger by revenue
IONS
IONS
1.8× larger
IONS
$203.3M
$114.9M
DLTH
Growing faster (revenue YoY)
DLTH
DLTH
+0.7% gap
DLTH
-9.6%
-10.3%
IONS
Higher net margin
DLTH
DLTH
104.0% more per $
DLTH
-8.8%
-112.8%
IONS
More free cash flow
DLTH
DLTH
$150.1M more FCF
DLTH
$-8.9M
$-159.0M
IONS
Faster 2-yr revenue CAGR
IONS
IONS
Annualised
IONS
30.4%
-31.6%
DLTH

Income Statement — Q3 FY2026 vs Q4 FY2025

Metric
DLTH
DLTH
IONS
IONS
Revenue
$114.9M
$203.3M
Net Profit
$-10.1M
$-229.4M
Gross Margin
53.8%
96.1%
Operating Margin
-7.7%
-105.5%
Net Margin
-8.8%
-112.8%
Revenue YoY
-9.6%
-10.3%
Net Profit YoY
64.6%
-119.8%
EPS (diluted)
$-0.29
$-1.35

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
DLTH
DLTH
IONS
IONS
Q4 25
$114.9M
$203.3M
Q3 25
$131.7M
$156.7M
Q2 25
$102.7M
$452.0M
Q1 25
$241.3M
$131.6M
Q4 24
$127.1M
$226.6M
Q3 24
$141.6M
$133.8M
Q2 24
$116.7M
$225.3M
Q1 24
$245.6M
$119.5M
Net Profit
DLTH
DLTH
IONS
IONS
Q4 25
$-10.1M
$-229.4M
Q3 25
$1.3M
$-128.6M
Q2 25
$-15.3M
$123.6M
Q1 25
$-5.6M
$-146.9M
Q4 24
$-28.2M
$-104.3M
Q3 24
$-2.0M
$-140.5M
Q2 24
$-7.9M
$-66.3M
Q1 24
$6.4M
$-142.8M
Gross Margin
DLTH
DLTH
IONS
IONS
Q4 25
53.8%
96.1%
Q3 25
54.7%
98.5%
Q2 25
52.0%
99.1%
Q1 25
44.1%
98.9%
Q4 24
52.3%
98.3%
Q3 24
52.3%
99.2%
Q2 24
52.8%
98.2%
Q1 24
48.2%
98.2%
Operating Margin
DLTH
DLTH
IONS
IONS
Q4 25
-7.7%
-105.5%
Q3 25
1.8%
-102.2%
Q2 25
-12.0%
30.9%
Q1 25
-1.8%
-111.6%
Q4 24
-17.4%
-48.9%
Q3 24
-1.1%
-111.1%
Q2 24
-7.7%
-29.3%
Q1 24
3.6%
-125.1%
Net Margin
DLTH
DLTH
IONS
IONS
Q4 25
-8.8%
-112.8%
Q3 25
1.0%
-82.1%
Q2 25
-14.9%
27.3%
Q1 25
-2.3%
-111.6%
Q4 24
-22.2%
-46.1%
Q3 24
-1.4%
-105.0%
Q2 24
-6.7%
-29.4%
Q1 24
2.6%
-119.5%
EPS (diluted)
DLTH
DLTH
IONS
IONS
Q4 25
$-0.29
$-1.35
Q3 25
$0.04
$-0.80
Q2 25
$-0.45
$0.70
Q1 25
$-0.17
$-0.93
Q4 24
$-0.84
$-0.66
Q3 24
$-0.06
$-0.95
Q2 24
$-0.24
$-0.45
Q1 24
$0.20
$-0.98

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
DLTH
DLTH
IONS
IONS
Cash + ST InvestmentsLiquidity on hand
$8.2M
$2.7B
Total DebtLower is stronger
$1.8B
Stockholders' EquityBook value
$160.6M
$489.1M
Total Assets
$468.0M
$3.5B
Debt / EquityLower = less leverage
3.71×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
DLTH
DLTH
IONS
IONS
Q4 25
$8.2M
$2.7B
Q3 25
$5.7M
$2.2B
Q2 25
$8.6M
$2.3B
Q1 25
$3.3M
$2.1B
Q4 24
$9.3M
$2.3B
Q3 24
$9.8M
$2.5B
Q2 24
$6.8M
$2.1B
Q1 24
$32.2M
$2.2B
Total Debt
DLTH
DLTH
IONS
IONS
Q4 25
$1.8B
Q3 25
Q2 25
Q1 25
Q4 24
$1.3B
Q3 24
Q2 24
Q1 24
Stockholders' Equity
DLTH
DLTH
IONS
IONS
Q4 25
$160.6M
$489.1M
Q3 25
$170.0M
$618.0M
Q2 25
$167.9M
$631.7M
Q1 25
$182.7M
$475.7M
Q4 24
$188.1M
$588.4M
Q3 24
$215.7M
$662.5M
Q2 24
$218.4M
$263.7M
Q1 24
$222.8M
$296.5M
Total Assets
DLTH
DLTH
IONS
IONS
Q4 25
$468.0M
$3.5B
Q3 25
$433.8M
$3.0B
Q2 25
$463.7M
$3.0B
Q1 25
$452.4M
$2.8B
Q4 24
$533.1M
$3.0B
Q3 24
$488.6M
$3.1B
Q2 24
$471.4M
$2.7B
Q1 24
$491.2M
$2.8B
Debt / Equity
DLTH
DLTH
IONS
IONS
Q4 25
3.71×
Q3 25
Q2 25
Q1 25
Q4 24
2.13×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
DLTH
DLTH
IONS
IONS
Operating Cash FlowLast quarter
$-6.7M
$-137.7M
Free Cash FlowOCF − Capex
$-8.9M
$-159.0M
FCF MarginFCF / Revenue
-7.8%
-78.2%
Capex IntensityCapex / Revenue
2.0%
10.5%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$1.7M
$-320.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
DLTH
DLTH
IONS
IONS
Q4 25
$-6.7M
$-137.7M
Q3 25
$32.0M
$-131.4M
Q2 25
$-56.5M
$151.3M
Q1 25
$41.2M
$-150.8M
Q4 24
$-41.1M
$-116.1M
Q3 24
$16.6M
$-115.0M
Q2 24
$-33.7M
$-119.9M
Q1 24
$69.7M
$-149.9M
Free Cash Flow
DLTH
DLTH
IONS
IONS
Q4 25
$-8.9M
$-159.0M
Q3 25
$29.8M
$-136.7M
Q2 25
$-57.8M
$139.0M
Q1 25
$38.7M
$-163.4M
Q4 24
$-43.7M
$-141.6M
Q3 24
$15.0M
$-124.0M
Q2 24
$-35.2M
$-126.1M
Q1 24
$60.6M
$-154.4M
FCF Margin
DLTH
DLTH
IONS
IONS
Q4 25
-7.8%
-78.2%
Q3 25
22.6%
-87.2%
Q2 25
-56.3%
30.8%
Q1 25
16.0%
-124.1%
Q4 24
-34.4%
-62.5%
Q3 24
10.6%
-92.7%
Q2 24
-30.2%
-56.0%
Q1 24
24.7%
-129.2%
Capex Intensity
DLTH
DLTH
IONS
IONS
Q4 25
2.0%
10.5%
Q3 25
1.7%
3.4%
Q2 25
1.3%
2.7%
Q1 25
1.0%
9.6%
Q4 24
2.1%
11.3%
Q3 24
1.2%
6.8%
Q2 24
1.3%
2.8%
Q1 24
3.7%
3.8%
Cash Conversion
DLTH
DLTH
IONS
IONS
Q4 25
Q3 25
25.40×
Q2 25
1.22×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
10.86×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

DLTH
DLTH

Sales Channel Directly To Consumer$67.4M59%
Sales Channel Through Intermediary$47.4M41%

IONS
IONS

Products$58.0M29%
Spinraza Royalties$54.0M27%
Collaborative Agreement Revenue$52.4M26%
Wainus Royalties$16.0M8%
Wainua Joint Development Revenue$9.6M5%
Other Commercial$7.6M4%
Other Royalties$5.7M3%

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