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Side-by-side financial comparison of ENBRIDGE INC (ENB) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

ENBRIDGE INC is the larger business by last-quarter revenue ($5.7B vs $3.2B, roughly 1.8× Vertex Pharmaceuticals). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 26.2%, a 11.1% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 5.3%). ENBRIDGE INC produced more free cash flow last quarter ($2.4B vs $348.6M). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs 7.6%).

Enbridge Inc. is a multinational pipeline and energy company headquartered in Calgary, Alberta, Canada. Enbridge owns and operates pipelines throughout Canada and the United States, transporting crude oil, natural gas, and natural gas liquids, and also generates renewable energy. Enbridge's pipeline system is the longest in North America and the largest oil export pipeline network in the world. Its crude oil system consists of 28,661 kilometres of pipelines. Its 38,300 kilometre natural gas p...

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

ENB vs VRTX — Head-to-Head

Bigger by revenue
ENB
ENB
1.8× larger
ENB
$5.7B
$3.2B
VRTX
Growing faster (revenue YoY)
VRTX
VRTX
+4.2% gap
VRTX
9.5%
5.3%
ENB
Higher net margin
VRTX
VRTX
11.1% more per $
VRTX
37.3%
26.2%
ENB
More free cash flow
ENB
ENB
$2.1B more FCF
ENB
$2.4B
$348.6M
VRTX
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
7.6%
ENB

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ENB
ENB
VRTX
VRTX
Revenue
$5.7B
$3.2B
Net Profit
$1.5B
$1.2B
Gross Margin
85.4%
Operating Margin
34.7%
37.8%
Net Margin
26.2%
37.3%
Revenue YoY
5.3%
9.5%
Net Profit YoY
246.2%
30.5%
EPS (diluted)
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ENB
ENB
VRTX
VRTX
Q4 25
$5.7B
$3.2B
Q3 25
$4.5B
$3.1B
Q2 25
$4.8B
$3.0B
Q1 25
$6.4B
$2.8B
Q4 24
$5.4B
$2.9B
Q3 24
$4.2B
$2.8B
Q2 24
$4.3B
$2.6B
Q1 24
$4.9B
$2.7B
Net Profit
ENB
ENB
VRTX
VRTX
Q4 25
$1.5B
$1.2B
Q3 25
$575.2M
$1.1B
Q2 25
$1.7B
$1.0B
Q1 25
$1.7B
$646.3M
Q4 24
$434.4M
$913.0M
Q3 24
$1.0B
$1.0B
Q2 24
$1.4B
$-3.6B
Q1 24
$1.1B
$1.1B
Gross Margin
ENB
ENB
VRTX
VRTX
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
7.5%
85.9%
Q1 24
26.2%
87.3%
Operating Margin
ENB
ENB
VRTX
VRTX
Q4 25
34.7%
37.8%
Q3 25
36.9%
38.6%
Q2 25
35.1%
38.8%
Q1 25
41.7%
22.7%
Q4 24
32.8%
35.2%
Q3 24
38.7%
40.3%
Q2 24
38.3%
-132.9%
Q1 24
40.0%
42.4%
Net Margin
ENB
ENB
VRTX
VRTX
Q4 25
26.2%
37.3%
Q3 25
12.8%
35.2%
Q2 25
34.9%
34.8%
Q1 25
26.8%
23.3%
Q4 24
8.0%
31.4%
Q3 24
24.3%
37.7%
Q2 24
32.8%
-135.8%
Q1 24
22.3%
40.9%
EPS (diluted)
ENB
ENB
VRTX
VRTX
Q4 25
$4.64
Q3 25
$4.20
Q2 25
$3.99
Q1 25
$2.49
Q4 24
$3.62
Q3 24
$4.01
Q2 24
$-13.92
Q1 24
$4.21

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ENB
ENB
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$798.6M
$6.6B
Total DebtLower is stronger
$72.2B
Stockholders' EquityBook value
$45.5B
$18.7B
Total Assets
$159.5B
$25.6B
Debt / EquityLower = less leverage
1.59×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ENB
ENB
VRTX
VRTX
Q4 25
$798.6M
$6.6B
Q3 25
$1.0B
$6.3B
Q2 25
$878.2M
$6.4B
Q1 25
$1.5B
$6.2B
Q4 24
$1.3B
$6.1B
Q3 24
$1.4B
$6.5B
Q2 24
$2.6B
$5.8B
Q1 24
$886.2M
$10.2B
Total Debt
ENB
ENB
VRTX
VRTX
Q4 25
$72.2B
Q3 25
$73.4B
Q2 25
$70.8B
Q1 25
$70.9B
Q4 24
$68.2B
Q3 24
$63.7B
Q2 24
$62.2B
Q1 24
$59.4B
Stockholders' Equity
ENB
ENB
VRTX
VRTX
Q4 25
$45.5B
$18.7B
Q3 25
$47.6B
$17.3B
Q2 25
$47.8B
$17.2B
Q1 25
$49.8B
$16.5B
Q4 24
$48.1B
$16.4B
Q3 24
$48.0B
$15.6B
Q2 24
$49.1B
$14.8B
Q1 24
$46.9B
$18.5B
Total Assets
ENB
ENB
VRTX
VRTX
Q4 25
$159.5B
$25.6B
Q3 25
$158.4B
$24.9B
Q2 25
$154.5B
$24.0B
Q1 25
$160.6B
$22.9B
Q4 24
$159.9B
$22.5B
Q3 24
$150.2B
$22.2B
Q2 24
$146.9B
$20.1B
Q1 24
$139.2B
$23.9B
Debt / Equity
ENB
ENB
VRTX
VRTX
Q4 25
1.59×
Q3 25
1.54×
Q2 25
1.48×
Q1 25
1.42×
Q4 24
1.42×
Q3 24
1.33×
Q2 24
1.27×
Q1 24
1.27×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ENB
ENB
VRTX
VRTX
Operating Cash FlowLast quarter
$9.0B
$498.0M
Free Cash FlowOCF − Capex
$2.4B
$348.6M
FCF MarginFCF / Revenue
42.0%
10.9%
Capex IntensityCapex / Revenue
114.3%
4.7%
Cash ConversionOCF / Net Profit
5.96×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ENB
ENB
VRTX
VRTX
Q4 25
$9.0B
$498.0M
Q3 25
$1.2B
Q2 25
$1.1B
Q1 25
$2.2B
$818.9M
Q4 24
$9.2B
$584.6M
Q3 24
$1.4B
Q2 24
$-3.8B
Q1 24
$2.3B
$1.3B
Free Cash Flow
ENB
ENB
VRTX
VRTX
Q4 25
$2.4B
$348.6M
Q3 25
$1.1B
Q2 25
$927.4M
Q1 25
$970.9M
$778.2M
Q4 24
$4.3B
$492.0M
Q3 24
$1.3B
Q2 24
$-3.8B
Q1 24
$1.4B
$1.2B
FCF Margin
ENB
ENB
VRTX
VRTX
Q4 25
42.0%
10.9%
Q3 25
37.0%
Q2 25
31.3%
Q1 25
15.1%
28.1%
Q4 24
79.0%
16.9%
Q3 24
47.0%
Q2 24
-144.5%
Q1 24
29.0%
46.0%
Capex Intensity
ENB
ENB
VRTX
VRTX
Q4 25
114.3%
4.7%
Q3 25
3.3%
Q2 25
4.9%
Q1 25
19.6%
1.5%
Q4 24
90.1%
3.2%
Q3 24
2.4%
Q2 24
2.6%
Q1 24
17.5%
2.5%
Cash Conversion
ENB
ENB
VRTX
VRTX
Q4 25
5.96×
0.42×
Q3 25
1.15×
Q2 25
1.04×
Q1 25
1.29×
1.27×
Q4 24
21.18×
0.64×
Q3 24
1.31×
Q2 24
Q1 24
2.08×
1.19×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ENB
ENB

Segment breakdown not available.

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

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