vs

Side-by-side financial comparison of RYDER SYSTEM INC (R) and Vertex Pharmaceuticals (VRTX). Click either name above to swap in a different company.

Vertex Pharmaceuticals is the larger business by last-quarter revenue ($3.2B vs $3.1B, roughly 1.0× RYDER SYSTEM INC). Vertex Pharmaceuticals runs the higher net margin — 37.3% vs 3.0%, a 34.4% gap on every dollar of revenue. On growth, Vertex Pharmaceuticals posted the faster year-over-year revenue change (9.5% vs 1.0%). Vertex Pharmaceuticals produced more free cash flow last quarter ($348.6M vs $273.0M). Over the past eight quarters, Vertex Pharmaceuticals's revenue compounded faster (8.9% CAGR vs -0.9%).

Ryder System, Inc. is an American transportation and logistics company, specializing in truck rental and leasing, fleet management, supply chain management, and transportation management. It also offers full-service leasing, rental and maintenance, used vehicle sales, transportation management, professional drivers, e-commerce fulfillment, and last-mile delivery services. The company is headquartered in Coral Gables, Florida, and operates in the United States and United Kingdom.

Vertex Pharmaceuticals Incorporated is an American biopharmaceutical company based in Boston, Massachusetts. It was one of the first biotech firms to use an explicit strategy of rational drug design rather than combinatorial chemistry. It maintains headquarters in Boston, Massachusetts, and three research facilities, in San Diego, California, and Milton Park, Oxfordshire, England.

R vs VRTX — Head-to-Head

Bigger by revenue
VRTX
VRTX
1.0× larger
VRTX
$3.2B
$3.1B
R
Growing faster (revenue YoY)
VRTX
VRTX
+8.5% gap
VRTX
9.5%
1.0%
R
Higher net margin
VRTX
VRTX
34.4% more per $
VRTX
37.3%
3.0%
R
More free cash flow
VRTX
VRTX
$75.6M more FCF
VRTX
$348.6M
$273.0M
R
Faster 2-yr revenue CAGR
VRTX
VRTX
Annualised
VRTX
8.9%
-0.9%
R

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
R
R
VRTX
VRTX
Revenue
$3.1B
$3.2B
Net Profit
$93.0M
$1.2B
Gross Margin
85.4%
Operating Margin
37.8%
Net Margin
3.0%
37.3%
Revenue YoY
1.0%
9.5%
Net Profit YoY
-5.1%
30.5%
EPS (diluted)
$2.34
$4.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
R
R
VRTX
VRTX
Q1 26
$3.1B
Q4 25
$3.2B
$3.2B
Q3 25
$3.2B
$3.1B
Q2 25
$3.2B
$3.0B
Q1 25
$3.1B
$2.8B
Q4 24
$3.2B
$2.9B
Q3 24
$3.2B
$2.8B
Q2 24
$3.2B
$2.6B
Net Profit
R
R
VRTX
VRTX
Q1 26
$93.0M
Q4 25
$132.0M
$1.2B
Q3 25
$138.0M
$1.1B
Q2 25
$131.0M
$1.0B
Q1 25
$98.0M
$646.3M
Q4 24
$135.0M
$913.0M
Q3 24
$142.0M
$1.0B
Q2 24
$127.0M
$-3.6B
Gross Margin
R
R
VRTX
VRTX
Q1 26
Q4 25
85.4%
Q3 25
86.5%
Q2 25
86.3%
Q1 25
86.9%
Q4 24
85.5%
Q3 24
85.8%
Q2 24
85.9%
Operating Margin
R
R
VRTX
VRTX
Q1 26
Q4 25
5.6%
37.8%
Q3 25
6.0%
38.6%
Q2 25
5.8%
38.8%
Q1 25
4.3%
22.7%
Q4 24
5.7%
35.2%
Q3 24
5.9%
40.3%
Q2 24
5.6%
-132.9%
Net Margin
R
R
VRTX
VRTX
Q1 26
3.0%
Q4 25
4.2%
37.3%
Q3 25
4.4%
35.2%
Q2 25
4.1%
34.8%
Q1 25
3.1%
23.3%
Q4 24
4.2%
31.4%
Q3 24
4.5%
37.7%
Q2 24
4.0%
-135.8%
EPS (diluted)
R
R
VRTX
VRTX
Q1 26
$2.34
Q4 25
$3.22
$4.64
Q3 25
$3.32
$4.20
Q2 25
$3.13
$3.99
Q1 25
$2.27
$2.49
Q4 24
$3.09
$3.62
Q3 24
$3.24
$4.01
Q2 24
$2.84
$-13.92

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
R
R
VRTX
VRTX
Cash + ST InvestmentsLiquidity on hand
$182.0M
$6.6B
Total DebtLower is stronger
Stockholders' EquityBook value
$2.9B
$18.7B
Total Assets
$25.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
R
R
VRTX
VRTX
Q1 26
$182.0M
Q4 25
$198.0M
$6.6B
Q3 25
$189.0M
$6.3B
Q2 25
$180.0M
$6.4B
Q1 25
$151.0M
$6.2B
Q4 24
$154.0M
$6.1B
Q3 24
$162.0M
$6.5B
Q2 24
$164.0M
$5.8B
Total Debt
R
R
VRTX
VRTX
Q1 26
Q4 25
$6.8B
Q3 25
$7.3B
Q2 25
$7.0B
Q1 25
$6.7B
Q4 24
$6.7B
Q3 24
$6.6B
Q2 24
$6.5B
Stockholders' Equity
R
R
VRTX
VRTX
Q1 26
$2.9B
Q4 25
$3.1B
$18.7B
Q3 25
$3.1B
$17.3B
Q2 25
$3.1B
$17.2B
Q1 25
$3.0B
$16.5B
Q4 24
$3.1B
$16.4B
Q3 24
$3.1B
$15.6B
Q2 24
$3.1B
$14.8B
Total Assets
R
R
VRTX
VRTX
Q1 26
Q4 25
$16.4B
$25.6B
Q3 25
$16.5B
$24.9B
Q2 25
$16.5B
$24.0B
Q1 25
$16.4B
$22.9B
Q4 24
$16.7B
$22.5B
Q3 24
$16.5B
$22.2B
Q2 24
$16.4B
$20.1B
Debt / Equity
R
R
VRTX
VRTX
Q1 26
Q4 25
2.24×
Q3 25
2.35×
Q2 25
2.27×
Q1 25
2.21×
Q4 24
2.14×
Q3 24
2.17×
Q2 24
2.09×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
R
R
VRTX
VRTX
Operating Cash FlowLast quarter
$583.0M
$498.0M
Free Cash FlowOCF − Capex
$273.0M
$348.6M
FCF MarginFCF / Revenue
8.7%
10.9%
Capex IntensityCapex / Revenue
13.7%
4.7%
Cash ConversionOCF / Net Profit
6.27×
0.42×
TTM Free Cash FlowTrailing 4 quarters
$595.0M
$3.2B

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
R
R
VRTX
VRTX
Q1 26
$583.0M
Q4 25
$749.0M
$498.0M
Q3 25
$442.0M
$1.2B
Q2 25
$752.0M
$1.1B
Q1 25
$651.0M
$818.9M
Q4 24
$558.0M
$584.6M
Q3 24
$629.0M
$1.4B
Q2 24
$552.0M
$-3.8B
Free Cash Flow
R
R
VRTX
VRTX
Q1 26
$273.0M
Q4 25
$344.0M
$348.6M
Q3 25
$-85.0M
$1.1B
Q2 25
$63.0M
$927.4M
Q1 25
$137.0M
$778.2M
Q4 24
$-201.0M
$492.0M
Q3 24
$30.0M
$1.3B
Q2 24
$-87.0M
$-3.8B
FCF Margin
R
R
VRTX
VRTX
Q1 26
8.7%
Q4 25
10.8%
10.9%
Q3 25
-2.7%
37.0%
Q2 25
2.0%
31.3%
Q1 25
4.4%
28.1%
Q4 24
-6.3%
16.9%
Q3 24
0.9%
47.0%
Q2 24
-2.7%
-144.5%
Capex Intensity
R
R
VRTX
VRTX
Q1 26
13.7%
Q4 25
12.8%
4.7%
Q3 25
16.6%
3.3%
Q2 25
21.6%
4.9%
Q1 25
16.4%
1.5%
Q4 24
23.8%
3.2%
Q3 24
18.9%
2.4%
Q2 24
20.1%
2.6%
Cash Conversion
R
R
VRTX
VRTX
Q1 26
6.27×
Q4 25
5.67×
0.42×
Q3 25
3.20×
1.15×
Q2 25
5.74×
1.04×
Q1 25
6.64×
1.27×
Q4 24
4.13×
0.64×
Q3 24
4.43×
1.31×
Q2 24
4.35×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

R
R

Fleet Management Solutions$1.5B47%
ChoiceLease$878.0M28%
Dedicated Transportation Solutions$553.0M18%
Commercial rental$211.0M7%

VRTX
VRTX

TRIKAFTAKAFTRIO$2.6B81%
ALYFTREK$380.1M12%
Manufactured Product Other$237.4M7%

Related Comparisons