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Side-by-side financial comparison of Esquire Financial Holdings, Inc. (ESQ) and NEKTAR THERAPEUTICS (NKTR). Click either name above to swap in a different company.

Esquire Financial Holdings, Inc. is the larger business by last-quarter revenue ($40.5M vs $21.8M, roughly 1.9× NEKTAR THERAPEUTICS). Esquire Financial Holdings, Inc. runs the higher net margin — 30.2% vs -165.4%, a 195.6% gap on every dollar of revenue. Over the past eight quarters, Esquire Financial Holdings, Inc.'s revenue compounded faster (15.0% CAGR vs 0.4%).

Esquire Financial Holdings, Inc. is a U.S.-headquartered bank holding company that provides comprehensive commercial and consumer banking products and services. Its core offerings include deposit accounts, business loans, mortgage services, and wealth management solutions, primarily serving small to medium enterprises, legal industry professionals, and local retail clients.

Nektar Therapeutics is an American biopharmaceutical company. The company was founded in 1990 and is based in San Francisco, California. The company develops new drug candidates by applying its proprietary PEGylation and advanced polymer conjugate technologies to modify chemical structure of substances, which improves drug characteristics like retention and solubility. It is a technology supplier to a number of pharmaceutical companies including Affymax, Amgen, Merck, Pfizer and UCB Pharma, e...

ESQ vs NKTR — Head-to-Head

Bigger by revenue
ESQ
ESQ
1.9× larger
ESQ
$40.5M
$21.8M
NKTR
Higher net margin
ESQ
ESQ
195.6% more per $
ESQ
30.2%
-165.4%
NKTR
Faster 2-yr revenue CAGR
ESQ
ESQ
Annualised
ESQ
15.0%
0.4%
NKTR

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
ESQ
ESQ
NKTR
NKTR
Revenue
$40.5M
$21.8M
Net Profit
$12.2M
$-36.1M
Gross Margin
Operating Margin
-126.9%
Net Margin
30.2%
-165.4%
Revenue YoY
-25.3%
Net Profit YoY
7.0%
-596.9%
EPS (diluted)
$1.40
$-4.67

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ESQ
ESQ
NKTR
NKTR
Q1 26
$40.5M
Q4 25
$39.4M
$21.8M
Q3 25
$37.6M
$11.8M
Q2 25
$35.8M
$11.2M
Q1 25
$33.8M
$10.5M
Q4 24
$33.1M
$29.2M
Q3 24
$31.9M
$24.1M
Q2 24
$30.6M
$23.5M
Net Profit
ESQ
ESQ
NKTR
NKTR
Q1 26
$12.2M
Q4 25
$13.5M
$-36.1M
Q3 25
$14.1M
$-35.5M
Q2 25
$11.9M
$-41.6M
Q1 25
$11.4M
$-50.9M
Q4 24
$11.8M
$7.3M
Q3 24
$11.4M
$-37.1M
Q2 24
$10.5M
$-52.4M
Gross Margin
ESQ
ESQ
NKTR
NKTR
Q1 26
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
72.7%
Q3 24
81.6%
Q2 24
58.5%
Operating Margin
ESQ
ESQ
NKTR
NKTR
Q1 26
Q4 25
44.3%
-126.9%
Q3 25
46.5%
-268.6%
Q2 25
42.5%
-324.2%
Q1 25
45.9%
-425.8%
Q4 24
47.4%
49.2%
Q3 24
48.8%
-142.4%
Q2 24
46.9%
-211.9%
Net Margin
ESQ
ESQ
NKTR
NKTR
Q1 26
30.2%
Q4 25
34.2%
-165.4%
Q3 25
37.4%
-301.3%
Q2 25
33.2%
-372.2%
Q1 25
33.8%
-486.4%
Q4 24
35.6%
24.9%
Q3 24
35.6%
-153.6%
Q2 24
34.3%
-222.9%
EPS (diluted)
ESQ
ESQ
NKTR
NKTR
Q1 26
$1.40
Q4 25
$1.54
$-4.67
Q3 25
$1.62
$-1.87
Q2 25
$1.38
$-2.95
Q1 25
$1.33
$-0.24
Q4 24
$1.35
$-2.07
Q3 24
$1.34
$-2.66
Q2 24
$1.25
$-3.76

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ESQ
ESQ
NKTR
NKTR
Cash + ST InvestmentsLiquidity on hand
$222.2M
$15.1M
Total DebtLower is stronger
Stockholders' EquityBook value
$301.3M
$89.8M
Total Assets
$2.4B
$280.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ESQ
ESQ
NKTR
NKTR
Q1 26
$222.2M
Q4 25
$235.9M
$15.1M
Q3 25
$240.8M
$41.0M
Q2 25
$163.0M
$43.0M
Q1 25
$173.0M
$38.9M
Q4 24
$126.3M
$44.3M
Q3 24
$147.7M
$30.1M
Q2 24
$152.7M
$27.9M
Stockholders' Equity
ESQ
ESQ
NKTR
NKTR
Q1 26
$301.3M
Q4 25
$289.6M
$89.8M
Q3 25
$279.2M
$85.1M
Q2 25
$263.6M
$-24.2M
Q1 25
$250.7M
$13.7M
Q4 24
$237.1M
$60.7M
Q3 24
$232.6M
$48.9M
Q2 24
$217.4M
$79.7M
Total Assets
ESQ
ESQ
NKTR
NKTR
Q1 26
$2.4B
Q4 25
$2.4B
$280.4M
Q3 25
$2.2B
$301.3M
Q2 25
$2.1B
$207.5M
Q1 25
$2.0B
$256.2M
Q4 24
$1.9B
$303.9M
Q3 24
$1.8B
$308.0M
Q2 24
$1.7B
$343.3M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ESQ
ESQ
NKTR
NKTR
Operating Cash FlowLast quarter
$-65.0M
Free Cash FlowOCF − Capex
$-65.0M
FCF MarginFCF / Revenue
-298.0%
Capex IntensityCapex / Revenue
0.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-208.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ESQ
ESQ
NKTR
NKTR
Q1 26
Q4 25
$59.8M
$-65.0M
Q3 25
$16.8M
$-48.8M
Q2 25
$10.5M
$-45.7M
Q1 25
$15.8M
$-49.1M
Q4 24
$42.2M
$-46.2M
Q3 24
$10.5M
$-43.9M
Q2 24
$7.2M
$-37.7M
Free Cash Flow
ESQ
ESQ
NKTR
NKTR
Q1 26
Q4 25
$56.7M
$-65.0M
Q3 25
$16.2M
$-48.9M
Q2 25
$9.3M
$-45.8M
Q1 25
$14.7M
$-49.1M
Q4 24
$41.5M
$-46.6M
Q3 24
$10.5M
$-44.6M
Q2 24
$6.9M
$-37.9M
FCF Margin
ESQ
ESQ
NKTR
NKTR
Q1 26
Q4 25
143.9%
-298.0%
Q3 25
43.2%
-414.5%
Q2 25
26.0%
-409.6%
Q1 25
43.4%
-469.0%
Q4 24
125.5%
-159.9%
Q3 24
32.8%
-184.9%
Q2 24
22.5%
-161.3%
Capex Intensity
ESQ
ESQ
NKTR
NKTR
Q1 26
Q4 25
8.0%
0.1%
Q3 25
1.3%
1.0%
Q2 25
3.2%
0.3%
Q1 25
3.4%
0.0%
Q4 24
2.2%
1.6%
Q3 24
0.2%
2.8%
Q2 24
1.1%
0.8%
Cash Conversion
ESQ
ESQ
NKTR
NKTR
Q1 26
Q4 25
4.44×
Q3 25
1.19×
Q2 25
0.88×
Q1 25
1.39×
Q4 24
3.59×
-6.36×
Q3 24
0.93×
Q2 24
0.69×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ESQ
ESQ

Net Interest Income$34.0M84%
Noninterest Income$6.5M16%

NKTR
NKTR

Segment breakdown not available.

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