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Side-by-side financial comparison of Eton Pharmaceuticals, Inc. (ETON) and Usio, Inc. (USIO). Click either name above to swap in a different company.

Usio, Inc. is the larger business by last-quarter revenue ($22.2M vs $21.3M, roughly 1.0× Eton Pharmaceuticals, Inc.). Eton Pharmaceuticals, Inc. runs the higher net margin — 7.0% vs -6.7%, a 13.7% gap on every dollar of revenue. On growth, Eton Pharmaceuticals, Inc. posted the faster year-over-year revenue change (82.7% vs 8.2%). Usio, Inc. produced more free cash flow last quarter ($1.1M vs $-11.6M). Over the past eight quarters, Eton Pharmaceuticals, Inc.'s revenue compounded faster (63.4% CAGR vs 3.0%).

Eton Pharmaceuticals, Inc. is a specialty pharmaceutical firm focused on developing and commercializing innovative therapies for rare diseases, pediatric care and hospital care segments. It mainly operates in the U.S. market, partnering with medical stakeholders to deliver accessible high-quality treatments to underserved patients.

Usio, Inc. is an American financial technology company headquartered in San Antonio, Texas. It provides integrated electronic payment services, including ACH processing, credit card and debit card acceptance, payment facilitation for software platforms, prepaid card issuing and a document print and mail operation.

ETON vs USIO — Head-to-Head

Bigger by revenue
USIO
USIO
1.0× larger
USIO
$22.2M
$21.3M
ETON
Growing faster (revenue YoY)
ETON
ETON
+74.5% gap
ETON
82.7%
8.2%
USIO
Higher net margin
ETON
ETON
13.7% more per $
ETON
7.0%
-6.7%
USIO
More free cash flow
USIO
USIO
$12.7M more FCF
USIO
$1.1M
$-11.6M
ETON
Faster 2-yr revenue CAGR
ETON
ETON
Annualised
ETON
63.4%
3.0%
USIO

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ETON
ETON
USIO
USIO
Revenue
$21.3M
$22.2M
Net Profit
$1.5M
$-1.5M
Gross Margin
61.6%
21.9%
Operating Margin
11.6%
-5.7%
Net Margin
7.0%
-6.7%
Revenue YoY
82.7%
8.2%
Net Profit YoY
348.0%
-337.8%
EPS (diluted)
$-0.05

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ETON
ETON
USIO
USIO
Q4 25
$21.3M
$22.2M
Q3 25
$22.5M
$21.2M
Q2 25
$18.9M
$20.0M
Q1 25
$17.3M
$22.0M
Q4 24
$11.6M
$20.6M
Q3 24
$10.3M
$21.3M
Q2 24
$9.1M
$20.1M
Q1 24
$8.0M
$21.0M
Net Profit
ETON
ETON
USIO
USIO
Q4 25
$1.5M
$-1.5M
Q3 25
$-1.9M
$-415.1K
Q2 25
$-2.6M
$-366.7K
Q1 25
$-1.6M
$-235.0K
Q4 24
$-598.0K
$628.9K
Q3 24
$627.0K
$2.9M
Q2 24
$-3.0M
$75.5K
Q1 24
$-811.0K
$-250.2K
Gross Margin
ETON
ETON
USIO
USIO
Q4 25
61.6%
21.9%
Q3 25
35.0%
23.0%
Q2 25
63.0%
25.8%
Q1 25
57.1%
21.9%
Q4 24
55.6%
24.6%
Q3 24
61.0%
23.0%
Q2 24
62.0%
23.9%
Q1 24
62.9%
23.1%
Operating Margin
ETON
ETON
USIO
USIO
Q4 25
11.6%
-5.7%
Q3 25
-6.1%
-2.2%
Q2 25
-7.8%
-2.0%
Q1 25
-2.7%
-1.1%
Q4 24
5.4%
-2.9%
Q3 24
4.9%
-1.8%
Q2 24
-32.3%
-1.0%
Q1 24
-10.0%
-1.3%
Net Margin
ETON
ETON
USIO
USIO
Q4 25
7.0%
-6.7%
Q3 25
-8.6%
-2.0%
Q2 25
-13.7%
-1.8%
Q1 25
-9.1%
-1.1%
Q4 24
-5.1%
3.1%
Q3 24
6.1%
13.4%
Q2 24
-33.5%
0.4%
Q1 24
-10.2%
-1.2%
EPS (diluted)
ETON
ETON
USIO
USIO
Q4 25
$-0.05
Q3 25
$-0.07
$-0.02
Q2 25
$-0.01
Q1 25
$-0.01
Q4 24
$0.03
Q3 24
$0.02
$0.10
Q2 24
$-0.12
$0.00
Q1 24
$-0.03
$-0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ETON
ETON
USIO
USIO
Cash + ST InvestmentsLiquidity on hand
$25.9M
$7.4M
Total DebtLower is stronger
$1.4M
Stockholders' EquityBook value
$26.2M
$17.9M
Total Assets
$92.1M
$134.9M
Debt / EquityLower = less leverage
0.08×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ETON
ETON
USIO
USIO
Q4 25
$25.9M
$7.4M
Q3 25
$37.1M
$7.7M
Q2 25
$25.4M
$8.1M
Q1 25
$17.4M
$8.7M
Q4 24
$14.9M
$8.1M
Q3 24
$20.3M
$8.4M
Q2 24
$17.7M
$7.2M
Q1 24
$16.7M
$7.1M
Total Debt
ETON
ETON
USIO
USIO
Q4 25
$1.4M
Q3 25
$836.7K
Q2 25
$647.1K
Q1 25
$30.0M
$683.3K
Q4 24
$29.8M
$719.4K
Q3 24
$562.9K
Q2 24
$597.2K
Q1 24
$630.9K
Stockholders' Equity
ETON
ETON
USIO
USIO
Q4 25
$26.2M
$17.9M
Q3 25
$23.1M
$18.7M
Q2 25
$24.0M
$18.7M
Q1 25
$24.4M
$19.0M
Q4 24
$24.4M
$19.2M
Q3 24
$16.0M
$18.9M
Q2 24
$13.5M
$15.7M
Q1 24
$15.5M
$15.3M
Total Assets
ETON
ETON
USIO
USIO
Q4 25
$92.1M
$134.9M
Q3 25
$104.5M
$99.4M
Q2 25
$101.7M
$108.4M
Q1 25
$84.0M
$109.6M
Q4 24
$76.1M
$107.2M
Q3 24
$35.8M
$114.6M
Q2 24
$31.8M
$108.8M
Q1 24
$30.8M
$99.1M
Debt / Equity
ETON
ETON
USIO
USIO
Q4 25
0.08×
Q3 25
0.04×
Q2 25
0.03×
Q1 25
1.23×
0.04×
Q4 24
1.22×
0.04×
Q3 24
0.03×
Q2 24
0.04×
Q1 24
0.04×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ETON
ETON
USIO
USIO
Operating Cash FlowLast quarter
$-11.6M
$1.5M
Free Cash FlowOCF − Capex
$-11.6M
$1.1M
FCF MarginFCF / Revenue
-54.5%
4.8%
Capex IntensityCapex / Revenue
0.2%
2.0%
Cash ConversionOCF / Net Profit
-7.79×
TTM Free Cash FlowTrailing 4 quarters
$1.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ETON
ETON
USIO
USIO
Q4 25
$-11.6M
$1.5M
Q3 25
$12.0M
$303.8K
Q2 25
$8.0M
$-263.9K
Q1 25
$2.1M
$1.4M
Q4 24
$-765.0K
$2.9M
Q3 24
$3.0M
$1.4M
Q2 24
$1.3M
$369.1K
Q1 24
$-2.5M
$88.7K
Free Cash Flow
ETON
ETON
USIO
USIO
Q4 25
$-11.6M
$1.1M
Q3 25
$11.7M
$85.2K
Q2 25
$-503.2K
Q1 25
$1.1M
Q4 24
$-777.0K
$2.7M
Q3 24
$1.4M
Q2 24
$246.3K
Q1 24
$-2.5M
$-88.1K
FCF Margin
ETON
ETON
USIO
USIO
Q4 25
-54.5%
4.8%
Q3 25
52.3%
0.4%
Q2 25
-2.5%
Q1 25
4.8%
Q4 24
-6.7%
13.1%
Q3 24
6.4%
Q2 24
1.2%
Q1 24
-31.2%
-0.4%
Capex Intensity
ETON
ETON
USIO
USIO
Q4 25
0.2%
2.0%
Q3 25
1.3%
1.0%
Q2 25
0.0%
1.2%
Q1 25
0.0%
1.4%
Q4 24
0.1%
1.0%
Q3 24
0.0%
0.3%
Q2 24
0.0%
0.6%
Q1 24
0.2%
0.8%
Cash Conversion
ETON
ETON
USIO
USIO
Q4 25
-7.79×
Q3 25
Q2 25
Q1 25
Q4 24
4.61×
Q3 24
4.71×
0.50×
Q2 24
4.89×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ETON
ETON

Segment breakdown not available.

USIO
USIO

Credit Card Revenue$7.7M35%
ACH And Complementary Service Revenue$6.1M28%
Output Solutions$5.4M24%
Prepaid Card Services Revenue$2.6M12%

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