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Side-by-side financial comparison of FIRST INTERSTATE BANCSYSTEM INC (FIBK) and Royalty Pharma plc (RPRX). Click either name above to swap in a different company.

Royalty Pharma plc is the larger business by last-quarter revenue ($622.0M vs $313.0M, roughly 2.0× FIRST INTERSTATE BANCSYSTEM INC). FIRST INTERSTATE BANCSYSTEM INC runs the higher net margin — 34.8% vs 34.4%, a 0.3% gap on every dollar of revenue. On growth, FIRST INTERSTATE BANCSYSTEM INC posted the faster year-over-year revenue change (19.8% vs 4.8%). Over the past eight quarters, FIRST INTERSTATE BANCSYSTEM INC's revenue compounded faster (13.7% CAGR vs 4.6%).

First Interstate BancSystem, Inc. is a financial holding company headquartered in Billings, Montana. It is the parent company of First Interstate Bank, a community bank with locations throughout 14 states within the Western and Midwestern United States. It is the largest bank based in Montana, as measured by total assets.

Acceleron Pharma, Inc. is an American clinical stage biopharmaceutical company based in Cambridge, Massachusetts with a broad focus on developing medicines that regulate the transforming growth factor beta (TGF-β) superfamily of proteins, which play fundamental roles in the growth and repair of cells and tissues such as red blood cells, muscle, bone, and blood vessels.

FIBK vs RPRX — Head-to-Head

Bigger by revenue
RPRX
RPRX
2.0× larger
RPRX
$622.0M
$313.0M
FIBK
Growing faster (revenue YoY)
FIBK
FIBK
+15.0% gap
FIBK
19.8%
4.8%
RPRX
Higher net margin
FIBK
FIBK
0.3% more per $
FIBK
34.8%
34.4%
RPRX
Faster 2-yr revenue CAGR
FIBK
FIBK
Annualised
FIBK
13.7%
4.6%
RPRX

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
FIBK
FIBK
RPRX
RPRX
Revenue
$313.0M
$622.0M
Net Profit
$108.8M
$214.2M
Gross Margin
Operating Margin
44.5%
62.4%
Net Margin
34.8%
34.4%
Revenue YoY
19.8%
4.8%
Net Profit YoY
108.8%
2.9%
EPS (diluted)
$1.07
$0.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FIBK
FIBK
RPRX
RPRX
Q4 25
$313.0M
$622.0M
Q3 25
$250.5M
$609.3M
Q2 25
$248.3M
$578.7M
Q1 25
$247.0M
$568.2M
Q4 24
$261.3M
$593.6M
Q3 24
$251.9M
$564.7M
Q2 24
$244.3M
$537.3M
Q1 24
$242.2M
$568.0M
Net Profit
FIBK
FIBK
RPRX
RPRX
Q4 25
$108.8M
$214.2M
Q3 25
$71.4M
$288.2M
Q2 25
$71.7M
$30.2M
Q1 25
$50.2M
$238.3M
Q4 24
$52.1M
$208.2M
Q3 24
$55.5M
$544.0M
Q2 24
$60.0M
$102.0M
Q1 24
$58.4M
$4.8M
Operating Margin
FIBK
FIBK
RPRX
RPRX
Q4 25
44.5%
62.4%
Q3 25
37.0%
70.1%
Q2 25
37.7%
36.3%
Q1 25
26.9%
94.0%
Q4 24
25.5%
60.9%
Q3 24
28.9%
Q2 24
32.1%
50.2%
Q1 24
31.7%
-13.0%
Net Margin
FIBK
FIBK
RPRX
RPRX
Q4 25
34.8%
34.4%
Q3 25
28.5%
47.3%
Q2 25
28.9%
5.2%
Q1 25
20.3%
41.9%
Q4 24
19.9%
35.1%
Q3 24
22.0%
96.3%
Q2 24
24.6%
19.0%
Q1 24
24.1%
0.8%
EPS (diluted)
FIBK
FIBK
RPRX
RPRX
Q4 25
$1.07
$0.49
Q3 25
$0.69
$0.67
Q2 25
$0.69
$0.07
Q1 25
$0.49
$0.55
Q4 24
$0.50
$0.46
Q3 24
$0.54
$1.21
Q2 24
$0.58
$0.23
Q1 24
$0.57
$0.01

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FIBK
FIBK
RPRX
RPRX
Cash + ST InvestmentsLiquidity on hand
$618.7M
Total DebtLower is stronger
$146.3M
$9.0B
Stockholders' EquityBook value
$3.4B
$9.7B
Total Assets
$26.6B
$19.6B
Debt / EquityLower = less leverage
0.04×
0.92×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FIBK
FIBK
RPRX
RPRX
Q4 25
$618.7M
Q3 25
$938.9M
Q2 25
$631.9M
Q1 25
$1.1B
Q4 24
$929.0M
Q3 24
$950.1M
Q2 24
$1.8B
Q1 24
$843.0M
Total Debt
FIBK
FIBK
RPRX
RPRX
Q4 25
$146.3M
$9.0B
Q3 25
$146.2M
$8.9B
Q2 25
$252.0M
$8.0B
Q1 25
$7.6B
Q4 24
$132.2M
$7.6B
Q3 24
$137.3M
$7.6B
Q2 24
$383.4M
$7.6B
Q1 24
$370.8M
$6.1B
Stockholders' Equity
FIBK
FIBK
RPRX
RPRX
Q4 25
$3.4B
$9.7B
Q3 25
$3.4B
$9.6B
Q2 25
$3.4B
$9.5B
Q1 25
$3.4B
$9.8B
Q4 24
$3.3B
$10.3B
Q3 24
$3.4B
$10.3B
Q2 24
$3.2B
$9.8B
Q1 24
$3.2B
$9.9B
Total Assets
FIBK
FIBK
RPRX
RPRX
Q4 25
$26.6B
$19.6B
Q3 25
$27.3B
$19.3B
Q2 25
$27.6B
$18.3B
Q1 25
$28.3B
$17.6B
Q4 24
$29.1B
$18.2B
Q3 24
$29.6B
$18.0B
Q2 24
$30.3B
$17.7B
Q1 24
$30.1B
$16.1B
Debt / Equity
FIBK
FIBK
RPRX
RPRX
Q4 25
0.04×
0.92×
Q3 25
0.04×
0.93×
Q2 25
0.07×
0.84×
Q1 25
0.78×
Q4 24
0.04×
0.74×
Q3 24
0.04×
0.74×
Q2 24
0.12×
0.78×
Q1 24
0.12×
0.62×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FIBK
FIBK
RPRX
RPRX
Operating Cash FlowLast quarter
$305.6M
$827.1M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
2.81×
3.86×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FIBK
FIBK
RPRX
RPRX
Q4 25
$305.6M
$827.1M
Q3 25
$91.7M
$702.6M
Q2 25
$68.1M
$364.0M
Q1 25
$78.5M
$596.1M
Q4 24
$355.0M
$742.5M
Q3 24
$89.9M
$703.6M
Q2 24
$82.3M
$658.2M
Q1 24
$87.6M
$664.6M
Cash Conversion
FIBK
FIBK
RPRX
RPRX
Q4 25
2.81×
3.86×
Q3 25
1.28×
2.44×
Q2 25
0.95×
12.06×
Q1 25
1.56×
2.50×
Q4 24
6.81×
3.57×
Q3 24
1.62×
1.29×
Q2 24
1.37×
6.45×
Q1 24
1.50×
139.10×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FIBK
FIBK

Segment breakdown not available.

RPRX
RPRX

Financial Royalty Assets$592.4M95%
Royalty Income Other$29.6M5%

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