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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and HighPeak Energy, Inc. (HPK). Click either name above to swap in a different company.

HighPeak Energy, Inc. is the larger business by last-quarter revenue ($216.6M vs $185.2M, roughly 1.2× AMICUS THERAPEUTICS, INC.). AMICUS THERAPEUTICS, INC. runs the higher net margin — 0.9% vs -11.6%, a 12.6% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs -23.3%). Over the past eight quarters, AMICUS THERAPEUTICS, INC.'s revenue compounded faster (29.5% CAGR vs -13.2%).

Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.

Duke Energy Corporation is an American electric power and natural gas holding company headquartered in Charlotte, North Carolina. The company serves over 7 million customers in the eastern United States. In 2024 it ranked as the 141st largest company in the United States – its highest-ever placement on the Fortune 500 list.

FOLD vs HPK — Head-to-Head

Bigger by revenue
HPK
HPK
1.2× larger
HPK
$216.6M
$185.2M
FOLD
Growing faster (revenue YoY)
FOLD
FOLD
+47.0% gap
FOLD
23.7%
-23.3%
HPK
Higher net margin
FOLD
FOLD
12.6% more per $
FOLD
0.9%
-11.6%
HPK
Faster 2-yr revenue CAGR
FOLD
FOLD
Annualised
FOLD
29.5%
-13.2%
HPK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
FOLD
FOLD
HPK
HPK
Revenue
$185.2M
$216.6M
Net Profit
$1.7M
$-25.2M
Gross Margin
85.7%
Operating Margin
8.6%
-7.6%
Net Margin
0.9%
-11.6%
Revenue YoY
23.7%
-23.3%
Net Profit YoY
-88.5%
-380.7%
EPS (diluted)
$0.00
$-0.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FOLD
FOLD
HPK
HPK
Q4 25
$185.2M
$216.6M
Q3 25
$169.1M
$188.9M
Q2 25
$154.7M
$200.4M
Q1 25
$125.2M
$257.4M
Q4 24
$149.7M
$282.6M
Q3 24
$141.5M
$271.6M
Q2 24
$126.7M
$275.3M
Q1 24
$110.4M
$287.8M
Net Profit
FOLD
FOLD
HPK
HPK
Q4 25
$1.7M
$-25.2M
Q3 25
$17.3M
$-18.3M
Q2 25
$-24.4M
$26.2M
Q1 25
$-21.7M
$36.3M
Q4 24
$14.7M
$9.0M
Q3 24
$-6.7M
$49.9M
Q2 24
$-15.7M
$29.7M
Q1 24
$-48.4M
$6.4M
Gross Margin
FOLD
FOLD
HPK
HPK
Q4 25
85.7%
Q3 25
88.5%
Q2 25
90.2%
Q1 25
90.7%
Q4 24
90.1%
Q3 24
90.6%
Q2 24
91.1%
Q1 24
87.7%
Operating Margin
FOLD
FOLD
HPK
HPK
Q4 25
8.6%
-7.6%
Q3 25
20.3%
17.3%
Q2 25
-6.1%
21.7%
Q1 25
-6.3%
35.1%
Q4 24
10.7%
26.1%
Q3 24
15.3%
27.0%
Q2 24
11.8%
31.7%
Q1 24
-25.1%
35.8%
Net Margin
FOLD
FOLD
HPK
HPK
Q4 25
0.9%
-11.6%
Q3 25
10.2%
-9.7%
Q2 25
-15.8%
13.1%
Q1 25
-17.3%
14.1%
Q4 24
9.8%
3.2%
Q3 24
-4.8%
18.4%
Q2 24
-12.4%
10.8%
Q1 24
-43.9%
2.2%
EPS (diluted)
FOLD
FOLD
HPK
HPK
Q4 25
$0.00
$-0.16
Q3 25
$0.06
$-0.15
Q2 25
$-0.08
$0.19
Q1 25
$-0.07
$0.26
Q4 24
$0.05
$0.06
Q3 24
$-0.02
$0.35
Q2 24
$-0.05
$0.21
Q1 24
$-0.16
$0.05

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FOLD
FOLD
HPK
HPK
Cash + ST InvestmentsLiquidity on hand
$293.5M
$162.1M
Total DebtLower is stronger
$392.7M
$1.2B
Stockholders' EquityBook value
$274.2M
$1.6B
Total Assets
$949.9M
$3.2B
Debt / EquityLower = less leverage
1.43×
0.75×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FOLD
FOLD
HPK
HPK
Q4 25
$293.5M
$162.1M
Q3 25
$263.8M
$164.9M
Q2 25
$231.0M
$21.9M
Q1 25
$250.6M
$51.6M
Q4 24
$249.9M
$86.6M
Q3 24
$249.8M
$135.6M
Q2 24
$260.1M
$157.9M
Q1 24
$239.6M
$173.4M
Total Debt
FOLD
FOLD
HPK
HPK
Q4 25
$392.7M
$1.2B
Q3 25
$392.0M
$1.2B
Q2 25
$391.3M
$1.0B
Q1 25
$390.7M
$1.0B
Q4 24
$390.1M
$1.0B
Q3 24
$389.5M
$1.1B
Q2 24
$388.9M
$1.1B
Q1 24
$388.4M
$1.1B
Stockholders' Equity
FOLD
FOLD
HPK
HPK
Q4 25
$274.2M
$1.6B
Q3 25
$230.4M
$1.6B
Q2 25
$204.3M
$1.7B
Q1 25
$193.6M
$1.6B
Q4 24
$194.0M
$1.6B
Q3 24
$178.8M
$1.6B
Q2 24
$132.5M
$1.6B
Q1 24
$130.7M
$1.5B
Total Assets
FOLD
FOLD
HPK
HPK
Q4 25
$949.9M
$3.2B
Q3 25
$868.8M
$3.2B
Q2 25
$815.3M
$3.1B
Q1 25
$789.8M
$3.1B
Q4 24
$785.0M
$3.1B
Q3 24
$786.6M
$3.1B
Q2 24
$749.5M
$3.1B
Q1 24
$721.8M
$3.1B
Debt / Equity
FOLD
FOLD
HPK
HPK
Q4 25
1.43×
0.75×
Q3 25
1.70×
0.73×
Q2 25
1.92×
0.62×
Q1 25
2.02×
0.63×
Q4 24
2.01×
0.65×
Q3 24
2.18×
0.67×
Q2 24
2.93×
0.70×
Q1 24
2.97×
0.73×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FOLD
FOLD
HPK
HPK
Operating Cash FlowLast quarter
$16.3M
$93.1M
Free Cash FlowOCF − Capex
$16.0M
FCF MarginFCF / Revenue
8.6%
Capex IntensityCapex / Revenue
0.2%
Cash ConversionOCF / Net Profit
9.62×
TTM Free Cash FlowTrailing 4 quarters
$29.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FOLD
FOLD
HPK
HPK
Q4 25
$16.3M
$93.1M
Q3 25
$35.7M
$120.2M
Q2 25
$-26.5M
$141.2M
Q1 25
$7.8M
$157.1M
Q4 24
$-3.9M
$139.5M
Q3 24
$-23.0M
$177.1M
Q2 24
$22.7M
$202.3M
Q1 24
$-29.7M
$171.4M
Free Cash Flow
FOLD
FOLD
HPK
HPK
Q4 25
$16.0M
Q3 25
$35.3M
Q2 25
$-28.9M
Q1 25
$7.5M
Q4 24
$-4.2M
Q3 24
$-23.3M
Q2 24
$21.6M
Q1 24
$-31.5M
FCF Margin
FOLD
FOLD
HPK
HPK
Q4 25
8.6%
Q3 25
20.9%
Q2 25
-18.7%
Q1 25
6.0%
Q4 24
-2.8%
Q3 24
-16.5%
Q2 24
17.0%
Q1 24
-28.5%
Capex Intensity
FOLD
FOLD
HPK
HPK
Q4 25
0.2%
Q3 25
0.2%
Q2 25
1.6%
Q1 25
0.2%
Q4 24
0.2%
Q3 24
0.3%
Q2 24
0.9%
Q1 24
1.6%
Cash Conversion
FOLD
FOLD
HPK
HPK
Q4 25
9.62×
Q3 25
2.06×
Q2 25
5.39×
Q1 25
4.32×
Q4 24
-0.27×
15.53×
Q3 24
3.55×
Q2 24
6.81×
Q1 24
26.63×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FOLD
FOLD

Other$105.8M57%
Galafold$64.8M35%
Pombiliti Opfolda$14.6M8%

HPK
HPK

Crude Oil Sales$152.1M70%
Natural Gas And NGL Sales$60.8M28%

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