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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and El Pollo Loco Holdings, Inc. (LOCO). Click either name above to swap in a different company.
AMICUS THERAPEUTICS, INC. is the larger business by last-quarter revenue ($185.2M vs $123.5M, roughly 1.5× El Pollo Loco Holdings, Inc.). El Pollo Loco Holdings, Inc. runs the higher net margin — 5.3% vs 0.9%, a 4.4% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs 8.1%). AMICUS THERAPEUTICS, INC. produced more free cash flow last quarter ($16.0M vs $5.1M). Over the past eight quarters, AMICUS THERAPEUTICS, INC.'s revenue compounded faster (29.5% CAGR vs 3.1%).
Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.
El Pollo Loco, Inc., is a restaurant chain based in the United States, specializing in Mexican-style grilled chicken. Restaurant service consists of dine-in and take-out, with some locations offering drive-through options. The company is headquartered in Costa Mesa, California, and operates about 500 company-owned and franchised restaurants in the Southwestern United States.
FOLD vs LOCO — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $185.2M | $123.5M |
| Net Profit | $1.7M | $6.5M |
| Gross Margin | 85.7% | — |
| Operating Margin | 8.6% | 8.3% |
| Net Margin | 0.9% | 5.3% |
| Revenue YoY | 23.7% | 8.1% |
| Net Profit YoY | -88.5% | 9.9% |
| EPS (diluted) | $0.00 | $0.22 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $185.2M | $123.5M | ||
| Q3 25 | $169.1M | $121.5M | ||
| Q2 25 | $154.7M | $125.8M | ||
| Q1 25 | $125.2M | $119.2M | ||
| Q4 24 | $149.7M | $114.3M | ||
| Q3 24 | $141.5M | $120.4M | ||
| Q2 24 | $126.7M | $122.2M | ||
| Q1 24 | $110.4M | $116.2M |
| Q4 25 | $1.7M | $6.5M | ||
| Q3 25 | $17.3M | $7.4M | ||
| Q2 25 | $-24.4M | $7.1M | ||
| Q1 25 | $-21.7M | $5.5M | ||
| Q4 24 | $14.7M | $6.0M | ||
| Q3 24 | $-6.7M | $6.2M | ||
| Q2 24 | $-15.7M | $7.6M | ||
| Q1 24 | $-48.4M | $5.9M |
| Q4 25 | 85.7% | — | ||
| Q3 25 | 88.5% | — | ||
| Q2 25 | 90.2% | — | ||
| Q1 25 | 90.7% | — | ||
| Q4 24 | 90.1% | — | ||
| Q3 24 | 90.6% | — | ||
| Q2 24 | 91.1% | — | ||
| Q1 24 | 87.7% | — |
| Q4 25 | 8.6% | 8.3% | ||
| Q3 25 | 20.3% | 9.4% | ||
| Q2 25 | -6.1% | 9.0% | ||
| Q1 25 | -6.3% | 7.5% | ||
| Q4 24 | 10.7% | 7.9% | ||
| Q3 24 | 15.3% | 8.4% | ||
| Q2 24 | 11.8% | 10.1% | ||
| Q1 24 | -25.1% | 8.3% |
| Q4 25 | 0.9% | 5.3% | ||
| Q3 25 | 10.2% | 6.1% | ||
| Q2 25 | -15.8% | 5.6% | ||
| Q1 25 | -17.3% | 4.6% | ||
| Q4 24 | 9.8% | 5.2% | ||
| Q3 24 | -4.8% | 5.1% | ||
| Q2 24 | -12.4% | 6.2% | ||
| Q1 24 | -43.9% | 5.1% |
| Q4 25 | $0.00 | $0.22 | ||
| Q3 25 | $0.06 | $0.25 | ||
| Q2 25 | $-0.08 | $0.24 | ||
| Q1 25 | $-0.07 | $0.19 | ||
| Q4 24 | $0.05 | $0.21 | ||
| Q3 24 | $-0.02 | $0.21 | ||
| Q2 24 | $-0.05 | $0.25 | ||
| Q1 24 | $-0.16 | $0.19 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $293.5M | $6.2M |
| Total DebtLower is stronger | $392.7M | $51.0M |
| Stockholders' EquityBook value | $274.2M | $291.1M |
| Total Assets | $949.9M | $606.6M |
| Debt / EquityLower = less leverage | 1.43× | 0.18× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $293.5M | $6.2M | ||
| Q3 25 | $263.8M | $10.9M | ||
| Q2 25 | $231.0M | $9.0M | ||
| Q1 25 | $250.6M | $4.3M | ||
| Q4 24 | $249.9M | $2.5M | ||
| Q3 24 | $249.8M | $7.9M | ||
| Q2 24 | $260.1M | $10.5M | ||
| Q1 24 | $239.6M | $9.1M |
| Q4 25 | $392.7M | $51.0M | ||
| Q3 25 | $392.0M | $61.0M | ||
| Q2 25 | $391.3M | $69.0M | ||
| Q1 25 | $390.7M | $73.0M | ||
| Q4 24 | $390.1M | $71.0M | ||
| Q3 24 | $389.5M | $76.0M | ||
| Q2 24 | $388.9M | $87.0M | ||
| Q1 24 | $388.4M | $80.0M |
| Q4 25 | $274.2M | $291.1M | ||
| Q3 25 | $230.4M | $282.9M | ||
| Q2 25 | $204.3M | $274.2M | ||
| Q1 25 | $193.6M | $265.7M | ||
| Q4 24 | $194.0M | $260.7M | ||
| Q3 24 | $178.8M | $255.2M | ||
| Q2 24 | $132.5M | $248.6M | ||
| Q1 24 | $130.7M | $256.3M |
| Q4 25 | $949.9M | $606.6M | ||
| Q3 25 | $868.8M | $602.7M | ||
| Q2 25 | $815.3M | $596.8M | ||
| Q1 25 | $789.8M | $590.5M | ||
| Q4 24 | $785.0M | $592.0M | ||
| Q3 24 | $786.6M | $590.0M | ||
| Q2 24 | $749.5M | $593.8M | ||
| Q1 24 | $721.8M | $598.0M |
| Q4 25 | 1.43× | 0.18× | ||
| Q3 25 | 1.70× | 0.22× | ||
| Q2 25 | 1.92× | 0.25× | ||
| Q1 25 | 2.02× | 0.27× | ||
| Q4 24 | 2.01× | 0.27× | ||
| Q3 24 | 2.18× | 0.30× | ||
| Q2 24 | 2.93× | 0.35× | ||
| Q1 24 | 2.97× | 0.31× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $16.3M | $13.9M |
| Free Cash FlowOCF − Capex | $16.0M | $5.1M |
| FCF MarginFCF / Revenue | 8.6% | 4.1% |
| Capex IntensityCapex / Revenue | 0.2% | 7.1% |
| Cash ConversionOCF / Net Profit | 9.62× | 2.13× |
| TTM Free Cash FlowTrailing 4 quarters | $29.8M | $25.4M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $16.3M | $13.9M | ||
| Q3 25 | $35.7M | $15.3M | ||
| Q2 25 | $-26.5M | $14.1M | ||
| Q1 25 | $7.8M | $4.7M | ||
| Q4 24 | $-3.9M | $5.6M | ||
| Q3 24 | $-23.0M | $13.0M | ||
| Q2 24 | $22.7M | $17.0M | ||
| Q1 24 | $-29.7M | $11.2M |
| Q4 25 | $16.0M | $5.1M | ||
| Q3 25 | $35.3M | $9.9M | ||
| Q2 25 | $-28.9M | $9.1M | ||
| Q1 25 | $7.5M | $1.3M | ||
| Q4 24 | $-4.2M | $1.1M | ||
| Q3 24 | $-23.3M | $9.1M | ||
| Q2 24 | $21.6M | $10.4M | ||
| Q1 24 | $-31.5M | $7.0M |
| Q4 25 | 8.6% | 4.1% | ||
| Q3 25 | 20.9% | 8.2% | ||
| Q2 25 | -18.7% | 7.2% | ||
| Q1 25 | 6.0% | 1.1% | ||
| Q4 24 | -2.8% | 1.0% | ||
| Q3 24 | -16.5% | 7.6% | ||
| Q2 24 | 17.0% | 8.5% | ||
| Q1 24 | -28.5% | 6.0% |
| Q4 25 | 0.2% | 7.1% | ||
| Q3 25 | 0.2% | 4.4% | ||
| Q2 25 | 1.6% | 4.0% | ||
| Q1 25 | 0.2% | 2.8% | ||
| Q4 24 | 0.2% | 3.9% | ||
| Q3 24 | 0.3% | 3.2% | ||
| Q2 24 | 0.9% | 5.3% | ||
| Q1 24 | 1.6% | 3.6% |
| Q4 25 | 9.62× | 2.13× | ||
| Q3 25 | 2.06× | 2.08× | ||
| Q2 25 | — | 1.99× | ||
| Q1 25 | — | 0.86× | ||
| Q4 24 | -0.27× | 0.95× | ||
| Q3 24 | — | 2.11× | ||
| Q2 24 | — | 2.22× | ||
| Q1 24 | — | 1.89× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
FOLD
| Other | $105.8M | 57% |
| Galafold | $64.8M | 35% |
| Pombiliti Opfolda | $14.6M | 8% |
LOCO
| Services | $102.4M | 83% |
| Franchise | $13.0M | 11% |
| Franchise Advertising Fee | $8.1M | 7% |
