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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and Ramaco Resources, Inc. (METC). Click either name above to swap in a different company.
AMICUS THERAPEUTICS, INC. is the larger business by last-quarter revenue ($185.2M vs $121.0M, roughly 1.5× Ramaco Resources, Inc.). AMICUS THERAPEUTICS, INC. runs the higher net margin — 0.9% vs -11.0%, a 11.9% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs -27.7%). AMICUS THERAPEUTICS, INC. produced more free cash flow last quarter ($16.0M vs $-17.5M). Over the past eight quarters, AMICUS THERAPEUTICS, INC.'s revenue compounded faster (29.5% CAGR vs -22.7%).
Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.
Ramaco Resources, Inc. is a U.S.-based mining company focused on high-grade metallurgical coal production. It operates mining assets across the Appalachian region, supplying products to global steel manufacturing and industrial clients, with core operations centered on sustainable low-cost metallurgical coal extraction and distribution.
FOLD vs METC — Head-to-Head
Income Statement — Q4 FY2025 vs Q3 FY2025
| Metric | | |
|---|---|---|
| Revenue | $185.2M | $121.0M |
| Net Profit | $1.7M | $-13.3M |
| Gross Margin | 85.7% | 15.8% |
| Operating Margin | 8.6% | -12.0% |
| Net Margin | 0.9% | -11.0% |
| Revenue YoY | 23.7% | -27.7% |
| Net Profit YoY | -88.5% | -5468.2% |
| EPS (diluted) | $0.00 | — |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $185.2M | — | ||
| Q3 25 | $169.1M | $121.0M | ||
| Q2 25 | $154.7M | $153.0M | ||
| Q1 25 | $125.2M | $134.7M | ||
| Q4 24 | $149.7M | $170.9M | ||
| Q3 24 | $141.5M | $167.4M | ||
| Q2 24 | $126.7M | $155.3M | ||
| Q1 24 | $110.4M | $172.7M |
| Q4 25 | $1.7M | — | ||
| Q3 25 | $17.3M | $-13.3M | ||
| Q2 25 | $-24.4M | $-14.0M | ||
| Q1 25 | $-21.7M | $-9.5M | ||
| Q4 24 | $14.7M | $3.9M | ||
| Q3 24 | $-6.7M | $-239.0K | ||
| Q2 24 | $-15.7M | $5.5M | ||
| Q1 24 | $-48.4M | $2.0M |
| Q4 25 | 85.7% | — | ||
| Q3 25 | 88.5% | 15.8% | ||
| Q2 25 | 90.2% | 12.3% | ||
| Q1 25 | 90.7% | 15.2% | ||
| Q4 24 | 90.1% | 20.4% | ||
| Q3 24 | 90.6% | 19.5% | ||
| Q2 24 | 91.1% | 21.0% | ||
| Q1 24 | 87.7% | 19.1% |
| Q4 25 | 8.6% | — | ||
| Q3 25 | 20.3% | -12.0% | ||
| Q2 25 | -6.1% | -9.1% | ||
| Q1 25 | -6.3% | -8.9% | ||
| Q4 24 | 10.7% | 3.7% | ||
| Q3 24 | 15.3% | 1.0% | ||
| Q2 24 | 11.8% | 3.5% | ||
| Q1 24 | -25.1% | 1.9% |
| Q4 25 | 0.9% | — | ||
| Q3 25 | 10.2% | -11.0% | ||
| Q2 25 | -15.8% | -9.1% | ||
| Q1 25 | -17.3% | -7.0% | ||
| Q4 24 | 9.8% | 2.3% | ||
| Q3 24 | -4.8% | -0.1% | ||
| Q2 24 | -12.4% | 3.6% | ||
| Q1 24 | -43.9% | 1.2% |
| Q4 25 | $0.00 | — | ||
| Q3 25 | $0.06 | — | ||
| Q2 25 | $-0.08 | — | ||
| Q1 25 | $-0.07 | — | ||
| Q4 24 | $0.05 | $0.06 | ||
| Q3 24 | $-0.02 | $-0.03 | ||
| Q2 24 | $-0.05 | $0.08 | ||
| Q1 24 | $-0.16 | $0.00 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $293.5M | $193.8M |
| Total DebtLower is stronger | $392.7M | $116.3M |
| Stockholders' EquityBook value | $274.2M | $526.9M |
| Total Assets | $949.9M | $849.7M |
| Debt / EquityLower = less leverage | 1.43× | 0.22× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $293.5M | — | ||
| Q3 25 | $263.8M | $193.8M | ||
| Q2 25 | $231.0M | $28.1M | ||
| Q1 25 | $250.6M | $43.5M | ||
| Q4 24 | $249.9M | $33.0M | ||
| Q3 24 | $249.8M | $22.9M | ||
| Q2 24 | $260.1M | $27.6M | ||
| Q1 24 | $239.6M | $30.5M |
| Q4 25 | $392.7M | — | ||
| Q3 25 | $392.0M | $116.3M | ||
| Q2 25 | $391.3M | — | ||
| Q1 25 | $390.7M | — | ||
| Q4 24 | $390.1M | $88.2M | ||
| Q3 24 | $389.5M | — | ||
| Q2 24 | $388.9M | — | ||
| Q1 24 | $388.4M | — |
| Q4 25 | $274.2M | — | ||
| Q3 25 | $230.4M | $526.9M | ||
| Q2 25 | $204.3M | $347.4M | ||
| Q1 25 | $193.6M | $355.2M | ||
| Q4 24 | $194.0M | $362.8M | ||
| Q3 24 | $178.8M | $361.8M | ||
| Q2 24 | $132.5M | $366.1M | ||
| Q1 24 | $130.7M | $372.3M |
| Q4 25 | $949.9M | — | ||
| Q3 25 | $868.8M | $849.7M | ||
| Q2 25 | $815.3M | $674.6M | ||
| Q1 25 | $789.8M | $685.7M | ||
| Q4 24 | $785.0M | $674.7M | ||
| Q3 24 | $786.6M | $645.4M | ||
| Q2 24 | $749.5M | $659.2M | ||
| Q1 24 | $721.8M | $674.0M |
| Q4 25 | 1.43× | — | ||
| Q3 25 | 1.70× | 0.22× | ||
| Q2 25 | 1.92× | — | ||
| Q1 25 | 2.02× | — | ||
| Q4 24 | 2.01× | 0.24× | ||
| Q3 24 | 2.18× | — | ||
| Q2 24 | 2.93× | — | ||
| Q1 24 | 2.97× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $16.3M | $-1.4M |
| Free Cash FlowOCF − Capex | $16.0M | $-17.5M |
| FCF MarginFCF / Revenue | 8.6% | -14.5% |
| Capex IntensityCapex / Revenue | 0.2% | 13.3% |
| Cash ConversionOCF / Net Profit | 9.62× | — |
| TTM Free Cash FlowTrailing 4 quarters | $29.8M | $-24.7M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $16.3M | — | ||
| Q3 25 | $35.7M | $-1.4M | ||
| Q2 25 | $-26.5M | $-4.3M | ||
| Q1 25 | $7.8M | $26.0M | ||
| Q4 24 | $-3.9M | $15.7M | ||
| Q3 24 | $-23.0M | $37.4M | ||
| Q2 24 | $22.7M | $34.4M | ||
| Q1 24 | $-29.7M | $25.2M |
| Q4 25 | $16.0M | — | ||
| Q3 25 | $35.3M | $-17.5M | ||
| Q2 25 | $-28.9M | $-19.8M | ||
| Q1 25 | $7.5M | $7.6M | ||
| Q4 24 | $-4.2M | $5.1M | ||
| Q3 24 | $-23.3M | $25.6M | ||
| Q2 24 | $21.6M | $20.3M | ||
| Q1 24 | $-31.5M | $6.5M |
| Q4 25 | 8.6% | — | ||
| Q3 25 | 20.9% | -14.5% | ||
| Q2 25 | -18.7% | -13.0% | ||
| Q1 25 | 6.0% | 5.6% | ||
| Q4 24 | -2.8% | 3.0% | ||
| Q3 24 | -16.5% | 15.3% | ||
| Q2 24 | 17.0% | 13.1% | ||
| Q1 24 | -28.5% | 3.7% |
| Q4 25 | 0.2% | — | ||
| Q3 25 | 0.2% | 13.3% | ||
| Q2 25 | 1.6% | 10.2% | ||
| Q1 25 | 0.2% | 13.7% | ||
| Q4 24 | 0.2% | 6.2% | ||
| Q3 24 | 0.3% | 7.0% | ||
| Q2 24 | 0.9% | 9.1% | ||
| Q1 24 | 1.6% | 10.8% |
| Q4 25 | 9.62× | — | ||
| Q3 25 | 2.06× | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | -0.27× | 4.06× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | 6.21× | ||
| Q1 24 | — | 12.40× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
FOLD
| Other | $105.8M | 57% |
| Galafold | $64.8M | 35% |
| Pombiliti Opfolda | $14.6M | 8% |
METC
| Export Coal Revenues | $73.0M | 60% |
| Domestic Coal Revenues | $48.0M | 40% |
