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Side-by-side financial comparison of AMICUS THERAPEUTICS, INC. (FOLD) and Wheels Up Experience Inc. (UP). Click either name above to swap in a different company.
AMICUS THERAPEUTICS, INC. is the larger business by last-quarter revenue ($185.2M vs $183.8M, roughly 1.0× Wheels Up Experience Inc.). AMICUS THERAPEUTICS, INC. runs the higher net margin — 0.9% vs -15.7%, a 16.6% gap on every dollar of revenue. On growth, AMICUS THERAPEUTICS, INC. posted the faster year-over-year revenue change (23.7% vs -10.2%). AMICUS THERAPEUTICS, INC. produced more free cash flow last quarter ($16.0M vs $-58.3M). Over the past eight quarters, AMICUS THERAPEUTICS, INC.'s revenue compounded faster (29.5% CAGR vs -3.4%).
Amicus Therapeutics, Inc. is a public American biopharmaceutical company based in Philadelphia, Pennsylvania. The company went public in 2007 under the Nasdaq trading symbol FOLD. This followed a 2006 planned offering and subsequent withdrawal, which would have established the trading symbol as AMTX Prior to their IPO, Amicus was funded by a variety of venture capital firms including Radius Ventures, Canaan Partners and New Enterprise Associates.
Wheels Up is a provider of "on demand" private aviation in the United States and one of the largest private aviation companies in the world. It was founded in 2013 by Kenny Dichter, using a membership/on-demand business model. Wheels Up members can book private aircraft from the company fleet and third-party operators using a mobile application.
FOLD vs UP — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $185.2M | $183.8M |
| Net Profit | $1.7M | $-28.9M |
| Gross Margin | 85.7% | 14.3% |
| Operating Margin | 8.6% | -0.9% |
| Net Margin | 0.9% | -15.7% |
| Revenue YoY | 23.7% | -10.2% |
| Net Profit YoY | -88.5% | 67.0% |
| EPS (diluted) | $0.00 | $-0.04 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $185.2M | $183.8M | ||
| Q3 25 | $169.1M | $185.5M | ||
| Q2 25 | $154.7M | $189.6M | ||
| Q1 25 | $125.2M | $177.5M | ||
| Q4 24 | $149.7M | $204.8M | ||
| Q3 24 | $141.5M | $193.9M | ||
| Q2 24 | $126.7M | $196.3M | ||
| Q1 24 | $110.4M | $197.1M |
| Q4 25 | $1.7M | $-28.9M | ||
| Q3 25 | $17.3M | $-83.7M | ||
| Q2 25 | $-24.4M | $-82.3M | ||
| Q1 25 | $-21.7M | $-99.3M | ||
| Q4 24 | $14.7M | $-87.5M | ||
| Q3 24 | $-6.7M | $-57.7M | ||
| Q2 24 | $-15.7M | $-97.0M | ||
| Q1 24 | $-48.4M | $-97.4M |
| Q4 25 | 85.7% | 14.3% | ||
| Q3 25 | 88.5% | 6.8% | ||
| Q2 25 | 90.2% | 8.3% | ||
| Q1 25 | 90.7% | 10.8% | ||
| Q4 24 | 90.1% | 13.9% | ||
| Q3 24 | 90.6% | 13.9% | ||
| Q2 24 | 91.1% | 2.3% | ||
| Q1 24 | 87.7% | -0.6% |
| Q4 25 | 8.6% | -0.9% | ||
| Q3 25 | 20.3% | -33.1% | ||
| Q2 25 | -6.1% | -31.4% | ||
| Q1 25 | -6.3% | -45.5% | ||
| Q4 24 | 10.7% | -26.0% | ||
| Q3 24 | 15.3% | -21.6% | ||
| Q2 24 | 11.8% | -40.3% | ||
| Q1 24 | -25.1% | -42.9% |
| Q4 25 | 0.9% | -15.7% | ||
| Q3 25 | 10.2% | -45.1% | ||
| Q2 25 | -15.8% | -43.4% | ||
| Q1 25 | -17.3% | -55.9% | ||
| Q4 24 | 9.8% | -42.7% | ||
| Q3 24 | -4.8% | -29.8% | ||
| Q2 24 | -12.4% | -49.4% | ||
| Q1 24 | -43.9% | -49.4% |
| Q4 25 | $0.00 | $-0.04 | ||
| Q3 25 | $0.06 | $-0.12 | ||
| Q2 25 | $-0.08 | $-0.12 | ||
| Q1 25 | $-0.07 | $-0.14 | ||
| Q4 24 | $0.05 | $-0.13 | ||
| Q3 24 | $-0.02 | $-0.08 | ||
| Q2 24 | $-0.05 | $-0.14 | ||
| Q1 24 | $-0.16 | $-0.14 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $293.5M | $133.9M |
| Total DebtLower is stronger | $392.7M | $671.3M |
| Stockholders' EquityBook value | $274.2M | $-392.1M |
| Total Assets | $949.9M | $968.8M |
| Debt / EquityLower = less leverage | 1.43× | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $293.5M | $133.9M | ||
| Q3 25 | $263.8M | $125.3M | ||
| Q2 25 | $231.0M | $107.0M | ||
| Q1 25 | $250.6M | $171.8M | ||
| Q4 24 | $249.9M | $216.4M | ||
| Q3 24 | $249.8M | $115.9M | ||
| Q2 24 | $260.1M | $141.5M | ||
| Q1 24 | $239.6M | $180.9M |
| Q4 25 | $392.7M | $671.3M | ||
| Q3 25 | $392.0M | $766.5M | ||
| Q2 25 | $391.3M | $770.5M | ||
| Q1 25 | $390.7M | $765.8M | ||
| Q4 24 | $390.1M | $761.3M | ||
| Q3 24 | $389.5M | $596.9M | ||
| Q2 24 | $388.9M | $597.4M | ||
| Q1 24 | $388.4M | $603.2M |
| Q4 25 | $274.2M | $-392.1M | ||
| Q3 25 | $230.4M | $-374.5M | ||
| Q2 25 | $204.3M | $-347.8M | ||
| Q1 25 | $193.6M | $-288.1M | ||
| Q4 24 | $194.0M | $-202.1M | ||
| Q3 24 | $178.8M | $-117.7M | ||
| Q2 24 | $132.5M | $-72.2M | ||
| Q1 24 | $130.7M | $936.0K |
| Q4 25 | $949.9M | $968.8M | ||
| Q3 25 | $868.8M | $973.0M | ||
| Q2 25 | $815.3M | $1.0B | ||
| Q1 25 | $789.8M | $1.1B | ||
| Q4 24 | $785.0M | $1.2B | ||
| Q3 24 | $786.6M | $1.0B | ||
| Q2 24 | $749.5M | $1.1B | ||
| Q1 24 | $721.8M | $1.2B |
| Q4 25 | 1.43× | — | ||
| Q3 25 | 1.70× | — | ||
| Q2 25 | 1.92× | — | ||
| Q1 25 | 2.02× | — | ||
| Q4 24 | 2.01× | — | ||
| Q3 24 | 2.18× | — | ||
| Q2 24 | 2.93× | — | ||
| Q1 24 | 2.97× | 644.43× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $16.3M | $-18.4M |
| Free Cash FlowOCF − Capex | $16.0M | $-58.3M |
| FCF MarginFCF / Revenue | 8.6% | -31.7% |
| Capex IntensityCapex / Revenue | 0.2% | 21.7% |
| Cash ConversionOCF / Net Profit | 9.62× | — |
| TTM Free Cash FlowTrailing 4 quarters | $29.8M | $-259.9M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $16.3M | $-18.4M | ||
| Q3 25 | $35.7M | $-37.1M | ||
| Q2 25 | $-26.5M | $-62.9M | ||
| Q1 25 | $7.8M | $-47.9M | ||
| Q4 24 | $-3.9M | $37.9M | ||
| Q3 24 | $-23.0M | $-16.9M | ||
| Q2 24 | $22.7M | $-25.2M | ||
| Q1 24 | $-29.7M | $-73.8M |
| Q4 25 | $16.0M | $-58.3M | ||
| Q3 25 | $35.3M | $-60.4M | ||
| Q2 25 | $-28.9M | $-78.6M | ||
| Q1 25 | $7.5M | $-62.6M | ||
| Q4 24 | $-4.2M | $-70.2M | ||
| Q3 24 | $-23.3M | $-21.9M | ||
| Q2 24 | $21.6M | $-30.8M | ||
| Q1 24 | $-31.5M | $-77.8M |
| Q4 25 | 8.6% | -31.7% | ||
| Q3 25 | 20.9% | -32.6% | ||
| Q2 25 | -18.7% | -41.5% | ||
| Q1 25 | 6.0% | -35.3% | ||
| Q4 24 | -2.8% | -34.3% | ||
| Q3 24 | -16.5% | -11.3% | ||
| Q2 24 | 17.0% | -15.7% | ||
| Q1 24 | -28.5% | -39.5% |
| Q4 25 | 0.2% | 21.7% | ||
| Q3 25 | 0.2% | 12.5% | ||
| Q2 25 | 1.6% | 8.3% | ||
| Q1 25 | 0.2% | 8.3% | ||
| Q4 24 | 0.2% | 52.8% | ||
| Q3 24 | 0.3% | 2.6% | ||
| Q2 24 | 0.9% | 2.9% | ||
| Q1 24 | 1.6% | 2.0% |
| Q4 25 | 9.62× | — | ||
| Q3 25 | 2.06× | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | -0.27× | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
FOLD
| Other | $105.8M | 57% |
| Galafold | $64.8M | 35% |
| Pombiliti Opfolda | $14.6M | 8% |
UP
Segment breakdown not available.
