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Side-by-side financial comparison of Fortrea Holdings Inc. (FTRE) and Guardant Health, Inc. (GH). Click either name above to swap in a different company.

Fortrea Holdings Inc. is the larger business by last-quarter revenue ($660.5M vs $281.3M, roughly 2.3× Guardant Health, Inc.). Fortrea Holdings Inc. runs the higher net margin — -4.9% vs -45.7%, a 40.8% gap on every dollar of revenue. On growth, Guardant Health, Inc. posted the faster year-over-year revenue change (39.4% vs -5.2%). Fortrea Holdings Inc. produced more free cash flow last quarter ($121.6M vs $-54.2M). Over the past eight quarters, Guardant Health, Inc.'s revenue compounded faster (29.2% CAGR vs -0.1%).

Fortrea Holdings Inc. is an American contract research organization organized in Delaware and headquartered in Durham, North Carolina with operations in 90 countries. Its customers are primarily in the pharmaceutical, biotechnology, and medical device industries.

Guardant Health, Inc. is an American biotechnology company based in Palo Alto, California. Co-founders Helmy Eltoukhy and AmirAli Talasaz serve as co-chief executive officers.

FTRE vs GH — Head-to-Head

Bigger by revenue
FTRE
FTRE
2.3× larger
FTRE
$660.5M
$281.3M
GH
Growing faster (revenue YoY)
GH
GH
+44.6% gap
GH
39.4%
-5.2%
FTRE
Higher net margin
FTRE
FTRE
40.8% more per $
FTRE
-4.9%
-45.7%
GH
More free cash flow
FTRE
FTRE
$175.8M more FCF
FTRE
$121.6M
$-54.2M
GH
Faster 2-yr revenue CAGR
GH
GH
Annualised
GH
29.2%
-0.1%
FTRE

Income Statement — Q4 2025 vs Q4 2025

Metric
FTRE
FTRE
GH
GH
Revenue
$660.5M
$281.3M
Net Profit
$-32.5M
$-128.5M
Gross Margin
64.6%
Operating Margin
-2.1%
-43.0%
Net Margin
-4.9%
-45.7%
Revenue YoY
-5.2%
39.4%
Net Profit YoY
46.9%
-15.8%
EPS (diluted)
$-0.25
$-1.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FTRE
FTRE
GH
GH
Q4 25
$660.5M
$281.3M
Q3 25
$701.3M
$265.2M
Q2 25
$710.3M
$232.1M
Q1 25
$651.3M
$203.5M
Q4 24
$697.0M
$201.8M
Q3 24
$674.9M
$191.5M
Q2 24
$662.4M
$177.2M
Q1 24
$662.1M
$168.5M
Net Profit
FTRE
FTRE
GH
GH
Q4 25
$-32.5M
$-128.5M
Q3 25
$-15.9M
$-92.7M
Q2 25
$-374.9M
$-99.9M
Q1 25
$-562.9M
$-95.2M
Q4 24
$-61.2M
$-111.0M
Q3 24
$-27.9M
$-107.8M
Q2 24
$-138.4M
$-102.6M
Q1 24
$-101.0M
$-115.0M
Gross Margin
FTRE
FTRE
GH
GH
Q4 25
64.6%
Q3 25
64.7%
Q2 25
65.0%
Q1 25
63.3%
Q4 24
61.6%
Q3 24
61.1%
Q2 24
59.1%
Q1 24
61.2%
Operating Margin
FTRE
FTRE
GH
GH
Q4 25
-2.1%
-43.0%
Q3 25
-1.2%
-37.3%
Q2 25
-46.5%
-45.9%
Q1 25
-79.9%
-54.6%
Q4 24
-8.0%
-62.4%
Q3 24
-2.7%
-61.3%
Q2 24
-7.7%
-56.8%
Q1 24
-5.6%
-59.2%
Net Margin
FTRE
FTRE
GH
GH
Q4 25
-4.9%
-45.7%
Q3 25
-2.3%
-35.0%
Q2 25
-52.8%
-43.0%
Q1 25
-86.4%
-46.8%
Q4 24
-8.8%
-55.0%
Q3 24
-4.1%
-56.3%
Q2 24
-20.9%
-57.9%
Q1 24
-15.3%
-68.2%
EPS (diluted)
FTRE
FTRE
GH
GH
Q4 25
$-0.25
$-1.01
Q3 25
$-0.17
$-0.74
Q2 25
$-4.14
$-0.80
Q1 25
$-6.25
$-0.77
Q4 24
$-0.68
$-0.90
Q3 24
$-0.31
$-0.88
Q2 24
$-1.55
$-0.84
Q1 24
$-1.13
$-0.94

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FTRE
FTRE
GH
GH
Cash + ST InvestmentsLiquidity on hand
$174.6M
$378.2M
Total DebtLower is stronger
$1.5B
Stockholders' EquityBook value
$563.5M
$-99.3M
Total Assets
$2.7B
$2.0B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FTRE
FTRE
GH
GH
Q4 25
$174.6M
$378.2M
Q3 25
$131.3M
$580.0M
Q2 25
$81.2M
$629.1M
Q1 25
$101.6M
$698.6M
Q4 24
$118.5M
$525.5M
Q3 24
$105.3M
$585.0M
Q2 24
$126.2M
$933.7M
Q1 24
$92.8M
$1.0B
Total Debt
FTRE
FTRE
GH
GH
Q4 25
$1.5B
Q3 25
$1.1B
Q2 25
$1.1B
Q1 25
$1.1B
Q4 24
$1.1B
Q3 24
Q2 24
Q1 24
Stockholders' Equity
FTRE
FTRE
GH
GH
Q4 25
$563.5M
$-99.3M
Q3 25
$580.8M
$-354.5M
Q2 25
$589.2M
$-305.5M
Q1 25
$858.8M
$-250.8M
Q4 24
$1.4B
$-139.6M
Q3 24
$1.5B
$-60.1M
Q2 24
$1.5B
$-1.6M
Q1 24
$1.6B
$68.3M
Total Assets
FTRE
FTRE
GH
GH
Q4 25
$2.7B
$2.0B
Q3 25
$2.7B
$1.3B
Q2 25
$2.8B
$1.3B
Q1 25
$3.1B
$1.3B
Q4 24
$3.6B
$1.5B
Q3 24
$3.7B
$1.5B
Q2 24
$3.6B
$1.6B
Q1 24
$4.2B
$1.7B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FTRE
FTRE
GH
GH
Operating Cash FlowLast quarter
$129.1M
$-26.4M
Free Cash FlowOCF − Capex
$121.6M
$-54.2M
FCF MarginFCF / Revenue
18.4%
-19.3%
Capex IntensityCapex / Revenue
1.1%
9.9%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$88.3M
$-233.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FTRE
FTRE
GH
GH
Q4 25
$129.1M
$-26.4M
Q3 25
$86.8M
$-35.4M
Q2 25
$21.8M
$-60.3M
Q1 25
$-124.2M
$-62.7M
Q4 24
$17.1M
$-64.5M
Q3 24
$-2.4M
$-51.1M
Q2 24
$273.7M
$-94.0M
Q1 24
$-25.6M
$-30.3M
Free Cash Flow
FTRE
FTRE
GH
GH
Q4 25
$121.6M
$-54.2M
Q3 25
$79.5M
$-45.8M
Q2 25
$14.3M
$-65.9M
Q1 25
$-127.1M
$-67.1M
Q4 24
$13.9M
$-83.4M
Q3 24
$-10.6M
$-55.3M
Q2 24
$262.5M
$-99.1M
Q1 24
$-34.9M
$-37.2M
FCF Margin
FTRE
FTRE
GH
GH
Q4 25
18.4%
-19.3%
Q3 25
11.3%
-17.3%
Q2 25
2.0%
-28.4%
Q1 25
-19.5%
-33.0%
Q4 24
2.0%
-41.3%
Q3 24
-1.6%
-28.9%
Q2 24
39.6%
-55.9%
Q1 24
-5.3%
-22.1%
Capex Intensity
FTRE
FTRE
GH
GH
Q4 25
1.1%
9.9%
Q3 25
1.0%
3.9%
Q2 25
1.1%
2.4%
Q1 25
0.4%
2.2%
Q4 24
0.5%
9.4%
Q3 24
1.2%
2.2%
Q2 24
1.7%
2.9%
Q1 24
1.4%
4.1%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FTRE
FTRE

Segment breakdown not available.

GH
GH

Oncology$189.9M68%
Biopharma Data$54.0M19%
Screening$35.1M12%
Licensing Other$2.2M1%

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