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Side-by-side financial comparison of Fortrea Holdings Inc. (FTRE) and GRAIL, Inc. (GRAL). Click either name above to swap in a different company.

Fortrea Holdings Inc. is the larger business by last-quarter revenue ($660.5M vs $43.6M, roughly 15.2× GRAIL, Inc.). Fortrea Holdings Inc. runs the higher net margin — -4.9% vs -227.5%, a 222.6% gap on every dollar of revenue. On growth, GRAIL, Inc. posted the faster year-over-year revenue change (14.0% vs -5.2%). Fortrea Holdings Inc. produced more free cash flow last quarter ($121.6M vs $-63.9M). Over the past eight quarters, GRAIL, Inc.'s revenue compounded faster (27.7% CAGR vs -0.1%).

Fortrea Holdings Inc. is an American contract research organization organized in Delaware and headquartered in Durham, North Carolina with operations in 90 countries. Its customers are primarily in the pharmaceutical, biotechnology, and medical device industries.

GRAIL, Inc. is an American biotechnology company based in Menlo Park, California founded in 2015 seeking to develop an early cancer screening test for people who do not have symptoms. As a startup it was a subsidiary of Illumina, which bought it outright in 2021.

FTRE vs GRAL — Head-to-Head

Bigger by revenue
FTRE
FTRE
15.2× larger
FTRE
$660.5M
$43.6M
GRAL
Growing faster (revenue YoY)
GRAL
GRAL
+19.2% gap
GRAL
14.0%
-5.2%
FTRE
Higher net margin
FTRE
FTRE
222.6% more per $
FTRE
-4.9%
-227.5%
GRAL
More free cash flow
FTRE
FTRE
$185.5M more FCF
FTRE
$121.6M
$-63.9M
GRAL
Faster 2-yr revenue CAGR
GRAL
GRAL
Annualised
GRAL
27.7%
-0.1%
FTRE

Income Statement — Q4 2025 vs Q4 2025

Metric
FTRE
FTRE
GRAL
GRAL
Revenue
$660.5M
$43.6M
Net Profit
$-32.5M
$-99.2M
Gross Margin
Operating Margin
-2.1%
-285.4%
Net Margin
-4.9%
-227.5%
Revenue YoY
-5.2%
14.0%
Net Profit YoY
46.9%
-2.2%
EPS (diluted)
$-0.25
$-2.37

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
FTRE
FTRE
GRAL
GRAL
Q4 25
$660.5M
$43.6M
Q3 25
$701.3M
$36.2M
Q2 25
$710.3M
$35.5M
Q1 25
$651.3M
$31.8M
Q4 24
$697.0M
$38.3M
Q3 24
$674.9M
$28.7M
Q2 24
$662.4M
$32.0M
Q1 24
$662.1M
$26.7M
Net Profit
FTRE
FTRE
GRAL
GRAL
Q4 25
$-32.5M
$-99.2M
Q3 25
$-15.9M
$-89.0M
Q2 25
$-374.9M
$-114.0M
Q1 25
$-562.9M
$-106.2M
Q4 24
$-61.2M
$-97.1M
Q3 24
$-27.9M
$-125.7M
Q2 24
$-138.4M
$-1.6B
Q1 24
$-101.0M
$-218.9M
Operating Margin
FTRE
FTRE
GRAL
GRAL
Q4 25
-2.1%
-285.4%
Q3 25
-1.2%
-346.2%
Q2 25
-46.5%
-446.9%
Q1 25
-79.9%
-482.5%
Q4 24
-8.0%
-358.0%
Q3 24
-2.7%
-640.5%
Q2 24
-7.7%
-5133.8%
Q1 24
-5.6%
-851.1%
Net Margin
FTRE
FTRE
GRAL
GRAL
Q4 25
-4.9%
-227.5%
Q3 25
-2.3%
-245.8%
Q2 25
-52.8%
-320.7%
Q1 25
-86.4%
-333.6%
Q4 24
-8.8%
-253.8%
Q3 24
-4.1%
-438.7%
Q2 24
-20.9%
-4958.8%
Q1 24
-15.3%
-819.3%
EPS (diluted)
FTRE
FTRE
GRAL
GRAL
Q4 25
$-0.25
$-2.37
Q3 25
$-0.17
$-2.46
Q2 25
$-4.14
$-3.18
Q1 25
$-6.25
$-3.10
Q4 24
$-0.68
$-1.49
Q3 24
$-0.31
$-3.94
Q2 24
$-1.55
$-51.06
Q1 24
$-1.13
$-7.05

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
FTRE
FTRE
GRAL
GRAL
Cash + ST InvestmentsLiquidity on hand
$174.6M
$249.7M
Total DebtLower is stronger
Stockholders' EquityBook value
$563.5M
$2.6B
Total Assets
$2.7B
$2.9B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
FTRE
FTRE
GRAL
GRAL
Q4 25
$174.6M
$249.7M
Q3 25
$131.3M
$126.9M
Q2 25
$81.2M
$127.4M
Q1 25
$101.6M
$133.9M
Q4 24
$118.5M
$214.2M
Q3 24
$105.3M
$853.6M
Q2 24
$126.2M
$958.8M
Q1 24
$92.8M
$199.7M
Stockholders' Equity
FTRE
FTRE
GRAL
GRAL
Q4 25
$563.5M
$2.6B
Q3 25
$580.8M
$2.2B
Q2 25
$589.2M
$2.3B
Q1 25
$858.8M
$2.4B
Q4 24
$1.4B
$2.5B
Q3 24
$1.5B
$2.6B
Q2 24
$1.5B
$2.7B
Q1 24
$1.6B
Total Assets
FTRE
FTRE
GRAL
GRAL
Q4 25
$2.7B
$2.9B
Q3 25
$2.7B
$2.6B
Q2 25
$2.8B
$2.7B
Q1 25
$3.1B
$2.8B
Q4 24
$3.6B
$3.0B
Q3 24
$3.7B
$3.1B
Q2 24
$3.6B
$3.3B
Q1 24
$4.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
FTRE
FTRE
GRAL
GRAL
Operating Cash FlowLast quarter
$129.1M
$-63.8M
Free Cash FlowOCF − Capex
$121.6M
$-63.9M
FCF MarginFCF / Revenue
18.4%
-146.5%
Capex IntensityCapex / Revenue
1.1%
0.2%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$88.3M
$-299.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
FTRE
FTRE
GRAL
GRAL
Q4 25
$129.1M
$-63.8M
Q3 25
$86.8M
$-63.2M
Q2 25
$21.8M
$-77.0M
Q1 25
$-124.2M
$-95.0M
Q4 24
$17.1M
Q3 24
$-2.4M
$-104.6M
Q2 24
$273.7M
$-171.8M
Q1 24
$-25.6M
$-207.3M
Free Cash Flow
FTRE
FTRE
GRAL
GRAL
Q4 25
$121.6M
$-63.9M
Q3 25
$79.5M
$-63.6M
Q2 25
$14.3M
$-77.3M
Q1 25
$-127.1M
$-95.1M
Q4 24
$13.9M
Q3 24
$-10.6M
$-105.6M
Q2 24
$262.5M
$-173.2M
Q1 24
$-34.9M
$-209.8M
FCF Margin
FTRE
FTRE
GRAL
GRAL
Q4 25
18.4%
-146.5%
Q3 25
11.3%
-175.8%
Q2 25
2.0%
-217.6%
Q1 25
-19.5%
-298.6%
Q4 24
2.0%
Q3 24
-1.6%
-368.4%
Q2 24
39.6%
-541.7%
Q1 24
-5.3%
-785.3%
Capex Intensity
FTRE
FTRE
GRAL
GRAL
Q4 25
1.1%
0.2%
Q3 25
1.0%
1.1%
Q2 25
1.1%
1.0%
Q1 25
0.4%
0.2%
Q4 24
0.5%
Q3 24
1.2%
3.4%
Q2 24
1.7%
4.3%
Q1 24
1.4%
9.5%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

FTRE
FTRE

Segment breakdown not available.

GRAL
GRAL

Screening Revenue$42.3M97%
Developmental Services Revenue$1.3M3%

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