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Side-by-side financial comparison of Guardant Health, Inc. (GH) and INNOSPEC INC. (IOSP). Click either name above to swap in a different company.

INNOSPEC INC. is the larger business by last-quarter revenue ($453.2M vs $281.3M, roughly 1.6× Guardant Health, Inc.). INNOSPEC INC. runs the higher net margin — 6.8% vs -45.7%, a 52.5% gap on every dollar of revenue. On growth, Guardant Health, Inc. posted the faster year-over-year revenue change (39.4% vs 2.8%). Over the past eight quarters, Guardant Health, Inc.'s revenue compounded faster (29.2% CAGR vs 2.1%).

Guardant Health, Inc. is an American biotechnology company based in Palo Alto, California. Co-founders Helmy Eltoukhy and AmirAli Talasaz serve as co-chief executive officers.

Innospec Inc., formerly known as Octel Corporation and Associated Octel Company, Ltd., is an American specialty chemical company. It comprises three business units:The Performance Chemicals business trades in the personal care, home care, agrochemical, mining and industrial markets. The Fuel Specialties business specializes in manufacturing and supplying fuel additives. The Oilfield Services business supplies drilling, completion and production chemicals.

GH vs IOSP — Head-to-Head

Bigger by revenue
IOSP
IOSP
1.6× larger
IOSP
$453.2M
$281.3M
GH
Growing faster (revenue YoY)
GH
GH
+36.6% gap
GH
39.4%
2.8%
IOSP
Higher net margin
IOSP
IOSP
52.5% more per $
IOSP
6.8%
-45.7%
GH
Faster 2-yr revenue CAGR
GH
GH
Annualised
GH
29.2%
2.1%
IOSP

Income Statement — Q4 FY2025 vs Q1 FY2026

Metric
GH
GH
IOSP
IOSP
Revenue
$281.3M
$453.2M
Net Profit
$-128.5M
$30.8M
Gross Margin
64.6%
27.3%
Operating Margin
-43.0%
8.1%
Net Margin
-45.7%
6.8%
Revenue YoY
39.4%
2.8%
Net Profit YoY
-15.8%
-8.3%
EPS (diluted)
$-1.01
$1.22

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GH
GH
IOSP
IOSP
Q1 26
$453.2M
Q4 25
$281.3M
$455.6M
Q3 25
$265.2M
$441.9M
Q2 25
$232.1M
$439.7M
Q1 25
$203.5M
$440.8M
Q4 24
$201.8M
$466.8M
Q3 24
$191.5M
$443.4M
Q2 24
$177.2M
$435.0M
Net Profit
GH
GH
IOSP
IOSP
Q1 26
$30.8M
Q4 25
$-128.5M
$47.4M
Q3 25
$-92.7M
$12.9M
Q2 25
$-99.9M
$23.5M
Q1 25
$-95.2M
$32.8M
Q4 24
$-111.0M
$-70.4M
Q3 24
$-107.8M
$33.4M
Q2 24
$-102.6M
$31.2M
Gross Margin
GH
GH
IOSP
IOSP
Q1 26
27.3%
Q4 25
64.6%
28.0%
Q3 25
64.7%
26.4%
Q2 25
65.0%
28.0%
Q1 25
63.3%
28.4%
Q4 24
61.6%
29.2%
Q3 24
61.1%
28.0%
Q2 24
59.1%
29.2%
Operating Margin
GH
GH
IOSP
IOSP
Q1 26
8.1%
Q4 25
-43.0%
10.3%
Q3 25
-37.3%
1.3%
Q2 25
-45.9%
7.8%
Q1 25
-54.6%
9.6%
Q4 24
-62.4%
8.8%
Q3 24
-61.3%
10.3%
Q2 24
-56.8%
9.4%
Net Margin
GH
GH
IOSP
IOSP
Q1 26
6.8%
Q4 25
-45.7%
10.4%
Q3 25
-35.0%
2.9%
Q2 25
-43.0%
5.3%
Q1 25
-46.8%
7.4%
Q4 24
-55.0%
-15.1%
Q3 24
-56.3%
7.5%
Q2 24
-57.9%
7.2%
EPS (diluted)
GH
GH
IOSP
IOSP
Q1 26
$1.22
Q4 25
$-1.01
$1.90
Q3 25
$-0.74
$0.52
Q2 25
$-0.80
$0.94
Q1 25
$-0.77
$1.31
Q4 24
$-0.90
$-2.80
Q3 24
$-0.88
$1.33
Q2 24
$-0.84
$1.24

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GH
GH
IOSP
IOSP
Cash + ST InvestmentsLiquidity on hand
$378.2M
$289.1M
Total DebtLower is stronger
$1.5B
Stockholders' EquityBook value
$-99.3M
$1.4B
Total Assets
$2.0B
$1.8B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GH
GH
IOSP
IOSP
Q1 26
$289.1M
Q4 25
$378.2M
$292.5M
Q3 25
$580.0M
$270.8M
Q2 25
$629.1M
$266.6M
Q1 25
$698.6M
$299.8M
Q4 24
$525.5M
$289.2M
Q3 24
$585.0M
$303.8M
Q2 24
$933.7M
$240.2M
Total Debt
GH
GH
IOSP
IOSP
Q1 26
Q4 25
$1.5B
Q3 25
$1.1B
Q2 25
$1.1B
Q1 25
$1.1B
Q4 24
$1.1B
Q3 24
Q2 24
Stockholders' Equity
GH
GH
IOSP
IOSP
Q1 26
$1.4B
Q4 25
$-99.3M
$1.3B
Q3 25
$-354.5M
$1.3B
Q2 25
$-305.5M
$1.3B
Q1 25
$-250.8M
$1.3B
Q4 24
$-139.6M
$1.2B
Q3 24
$-60.1M
$1.2B
Q2 24
$-1.6M
$1.2B
Total Assets
GH
GH
IOSP
IOSP
Q1 26
$1.8B
Q4 25
$2.0B
$1.8B
Q3 25
$1.3B
$1.8B
Q2 25
$1.3B
$1.8B
Q1 25
$1.3B
$1.8B
Q4 24
$1.5B
$1.7B
Q3 24
$1.5B
$1.8B
Q2 24
$1.6B
$1.7B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GH
GH
IOSP
IOSP
Operating Cash FlowLast quarter
$-26.4M
$17.6M
Free Cash FlowOCF − Capex
$-54.2M
FCF MarginFCF / Revenue
-19.3%
Capex IntensityCapex / Revenue
9.9%
2.0%
Cash ConversionOCF / Net Profit
0.57×
TTM Free Cash FlowTrailing 4 quarters
$-233.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GH
GH
IOSP
IOSP
Q1 26
$17.6M
Q4 25
$-26.4M
$61.4M
Q3 25
$-35.4M
$39.3M
Q2 25
$-60.3M
$9.3M
Q1 25
$-62.7M
$28.3M
Q4 24
$-64.5M
$25.7M
Q3 24
$-51.1M
$73.5M
Q2 24
$-94.0M
$4.7M
Free Cash Flow
GH
GH
IOSP
IOSP
Q1 26
Q4 25
$-54.2M
$46.8M
Q3 25
$-45.8M
$25.0M
Q2 25
$-65.9M
$-3.7M
Q1 25
$-67.1M
$19.9M
Q4 24
$-83.4M
$13.6M
Q3 24
$-55.3M
$65.8M
Q2 24
$-99.1M
$-6.2M
FCF Margin
GH
GH
IOSP
IOSP
Q1 26
Q4 25
-19.3%
10.3%
Q3 25
-17.3%
5.7%
Q2 25
-28.4%
-0.8%
Q1 25
-33.0%
4.5%
Q4 24
-41.3%
2.9%
Q3 24
-28.9%
14.8%
Q2 24
-55.9%
-1.4%
Capex Intensity
GH
GH
IOSP
IOSP
Q1 26
2.0%
Q4 25
9.9%
3.2%
Q3 25
3.9%
3.2%
Q2 25
2.4%
3.0%
Q1 25
2.2%
1.9%
Q4 24
9.4%
2.6%
Q3 24
2.2%
1.7%
Q2 24
2.9%
2.5%
Cash Conversion
GH
GH
IOSP
IOSP
Q1 26
0.57×
Q4 25
1.30×
Q3 25
3.05×
Q2 25
0.40×
Q1 25
0.86×
Q4 24
Q3 24
2.20×
Q2 24
0.15×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GH
GH

Oncology$189.9M68%
Biopharma Data$54.0M19%
Screening$35.1M12%
Licensing Other$2.2M1%

IOSP
IOSP

Segment breakdown not available.

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