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Side-by-side financial comparison of Guardant Health, Inc. (GH) and OneStream, Inc. (OS). Click either name above to swap in a different company.

Guardant Health, Inc. is the larger business by last-quarter revenue ($281.3M vs $163.7M, roughly 1.7× OneStream, Inc.). OneStream, Inc. runs the higher net margin — 0.6% vs -45.7%, a 46.3% gap on every dollar of revenue. On growth, Guardant Health, Inc. posted the faster year-over-year revenue change (39.4% vs 23.6%). OneStream, Inc. produced more free cash flow last quarter ($25.6M vs $-54.2M). Over the past eight quarters, Guardant Health, Inc.'s revenue compounded faster (29.2% CAGR vs 21.8%).

Guardant Health, Inc. is an American biotechnology company based in Palo Alto, California. Co-founders Helmy Eltoukhy and AmirAli Talasaz serve as co-chief executive officers.

Blue Stream provides cable television, cable telephone, DVR, and up to 1 GIG Internet speed broadband services to customers in the Florida communities of Coral Springs and Weston.

GH vs OS — Head-to-Head

Bigger by revenue
GH
GH
1.7× larger
GH
$281.3M
$163.7M
OS
Growing faster (revenue YoY)
GH
GH
+15.8% gap
GH
39.4%
23.6%
OS
Higher net margin
OS
OS
46.3% more per $
OS
0.6%
-45.7%
GH
More free cash flow
OS
OS
$79.9M more FCF
OS
$25.6M
$-54.2M
GH
Faster 2-yr revenue CAGR
GH
GH
Annualised
GH
29.2%
21.8%
OS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GH
GH
OS
OS
Revenue
$281.3M
$163.7M
Net Profit
$-128.5M
$999.0K
Gross Margin
64.6%
69.8%
Operating Margin
-43.0%
-3.2%
Net Margin
-45.7%
0.6%
Revenue YoY
39.4%
23.6%
Net Profit YoY
-15.8%
EPS (diluted)
$-1.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GH
GH
OS
OS
Q4 25
$281.3M
$163.7M
Q3 25
$265.2M
$154.3M
Q2 25
$232.1M
$147.6M
Q1 25
$203.5M
$136.3M
Q4 24
$201.8M
$132.5M
Q3 24
$191.5M
$129.1M
Q2 24
$177.2M
$117.5M
Q1 24
$168.5M
$110.3M
Net Profit
GH
GH
OS
OS
Q4 25
$-128.5M
$999.0K
Q3 25
$-92.7M
$-8.8M
Q2 25
$-99.9M
$-18.4M
Q1 25
$-95.2M
$-24.0M
Q4 24
$-111.0M
Q3 24
$-107.8M
$-171.9M
Q2 24
$-102.6M
$-7.8M
Q1 24
$-115.0M
$-5.0M
Gross Margin
GH
GH
OS
OS
Q4 25
64.6%
69.8%
Q3 25
64.7%
68.1%
Q2 25
65.0%
68.6%
Q1 25
63.3%
68.0%
Q4 24
61.6%
66.8%
Q3 24
61.1%
50.1%
Q2 24
59.1%
68.5%
Q1 24
61.2%
69.1%
Operating Margin
GH
GH
OS
OS
Q4 25
-43.0%
-3.2%
Q3 25
-37.3%
-11.3%
Q2 25
-45.9%
-21.8%
Q1 25
-54.6%
-29.3%
Q4 24
-62.4%
-35.8%
Q3 24
-61.3%
-197.6%
Q2 24
-56.8%
-9.8%
Q1 24
-59.2%
-4.9%
Net Margin
GH
GH
OS
OS
Q4 25
-45.7%
0.6%
Q3 25
-35.0%
-5.7%
Q2 25
-43.0%
-12.5%
Q1 25
-46.8%
-17.6%
Q4 24
-55.0%
Q3 24
-56.3%
-133.1%
Q2 24
-57.9%
-6.7%
Q1 24
-68.2%
-4.5%
EPS (diluted)
GH
GH
OS
OS
Q4 25
$-1.01
Q3 25
$-0.74
Q2 25
$-0.80
Q1 25
$-0.77
Q4 24
$-0.90
Q3 24
$-0.88
$-1.06
Q2 24
$-0.84
Q1 24
$-0.94

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GH
GH
OS
OS
Cash + ST InvestmentsLiquidity on hand
$378.2M
$693.6M
Total DebtLower is stronger
$1.5B
Stockholders' EquityBook value
$-99.3M
$504.7M
Total Assets
$2.0B
$1.0B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GH
GH
OS
OS
Q4 25
$378.2M
$693.6M
Q3 25
$580.0M
$653.9M
Q2 25
$629.1M
$652.1M
Q1 25
$698.6M
$593.9M
Q4 24
$525.5M
$544.2M
Q3 24
$585.0M
$495.5M
Q2 24
$933.7M
$140.5M
Q1 24
$1.0B
Total Debt
GH
GH
OS
OS
Q4 25
$1.5B
Q3 25
$1.1B
Q2 25
$1.1B
Q1 25
$1.1B
Q4 24
$1.1B
Q3 24
Q2 24
Q1 24
Stockholders' Equity
GH
GH
OS
OS
Q4 25
$-99.3M
$504.7M
Q3 25
$-354.5M
$472.1M
Q2 25
$-305.5M
$458.2M
Q1 25
$-250.8M
$412.9M
Q4 24
$-139.6M
$386.2M
Q3 24
$-60.1M
$458.2M
Q2 24
$-1.6M
$97.5M
Q1 24
$68.3M
$102.5M
Total Assets
GH
GH
OS
OS
Q4 25
$2.0B
$1.0B
Q3 25
$1.3B
$949.4M
Q2 25
$1.3B
$910.5M
Q1 25
$1.3B
$867.3M
Q4 24
$1.5B
$823.2M
Q3 24
$1.5B
$750.1M
Q2 24
$1.6B
$379.7M
Q1 24
$1.7B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GH
GH
OS
OS
Operating Cash FlowLast quarter
$-26.4M
$25.8M
Free Cash FlowOCF − Capex
$-54.2M
$25.6M
FCF MarginFCF / Revenue
-19.3%
15.7%
Capex IntensityCapex / Revenue
9.9%
0.1%
Cash ConversionOCF / Net Profit
25.79×
TTM Free Cash FlowTrailing 4 quarters
$-233.1M
$95.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GH
GH
OS
OS
Q4 25
$-26.4M
$25.8M
Q3 25
$-35.4M
$5.0M
Q2 25
$-60.3M
$29.7M
Q1 25
$-62.7M
$36.2M
Q4 24
$-64.5M
Q3 24
$-51.1M
$2.4M
Q2 24
$-94.0M
$8.1M
Q1 24
$-30.3M
$25.5M
Free Cash Flow
GH
GH
OS
OS
Q4 25
$-54.2M
$25.6M
Q3 25
$-45.8M
$4.8M
Q2 25
$-65.9M
$29.4M
Q1 25
$-67.1M
$35.8M
Q4 24
$-83.4M
Q3 24
$-55.3M
$1.3M
Q2 24
$-99.1M
$7.7M
Q1 24
$-37.2M
$24.9M
FCF Margin
GH
GH
OS
OS
Q4 25
-19.3%
15.7%
Q3 25
-17.3%
3.1%
Q2 25
-28.4%
19.9%
Q1 25
-33.0%
26.3%
Q4 24
-41.3%
Q3 24
-28.9%
1.0%
Q2 24
-55.9%
6.6%
Q1 24
-22.1%
22.5%
Capex Intensity
GH
GH
OS
OS
Q4 25
9.9%
0.1%
Q3 25
3.9%
0.1%
Q2 25
2.4%
0.2%
Q1 25
2.2%
0.3%
Q4 24
9.4%
Q3 24
2.2%
0.8%
Q2 24
2.9%
0.3%
Q1 24
4.1%
0.6%
Cash Conversion
GH
GH
OS
OS
Q4 25
25.79×
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GH
GH

Oncology$189.9M68%
Biopharma Data$54.0M19%
Screening$35.1M12%
Licensing Other$2.2M1%

OS
OS

Subscription And Circulation$150.3M92%
Professional Services And Other$9.4M6%
License$4.0M2%

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