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Side-by-side financial comparison of Guardant Health, Inc. (GH) and PicoCELA Inc. (PCLA). Click either name above to swap in a different company.

Guardant Health, Inc. is the larger business by last-quarter revenue ($281.3M vs $252.6M, roughly 1.1× PicoCELA Inc.). Guardant Health, Inc. runs the higher net margin — -45.7% vs -125.2%, a 79.5% gap on every dollar of revenue. Guardant Health, Inc. produced more free cash flow last quarter ($-54.2M vs $-256.6M).

Guardant Health, Inc. is an American biotechnology company based in Palo Alto, California. Co-founders Helmy Eltoukhy and AmirAli Talasaz serve as co-chief executive officers.

PicoCELA Inc. is a global technology company specializing in low-power, high-reliability wireless connectivity solutions, including Wi-Fi HaLow modules and edge network infrastructure. It caters to industrial IoT, smart city, retail, and smart home segments, with a primary operational footprint across Asia, North America, and European markets.

GH vs PCLA — Head-to-Head

Bigger by revenue
GH
GH
1.1× larger
GH
$281.3M
$252.6M
PCLA
Higher net margin
GH
GH
79.5% more per $
GH
-45.7%
-125.2%
PCLA
More free cash flow
GH
GH
$202.4M more FCF
GH
$-54.2M
$-256.6M
PCLA

Income Statement — Q4 FY2025 vs Q2 FY2025

Metric
GH
GH
PCLA
PCLA
Revenue
$281.3M
$252.6M
Net Profit
$-128.5M
$-316.2M
Gross Margin
64.6%
Operating Margin
-43.0%
-114.8%
Net Margin
-45.7%
-125.2%
Revenue YoY
39.4%
Net Profit YoY
-15.8%
EPS (diluted)
$-1.01

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GH
GH
PCLA
PCLA
Q4 25
$281.3M
Q3 25
$265.2M
Q2 25
$232.1M
Q1 25
$203.5M
$252.6M
Q4 24
$201.8M
Q3 24
$191.5M
Q2 24
$177.2M
Q1 24
$168.5M
Net Profit
GH
GH
PCLA
PCLA
Q4 25
$-128.5M
Q3 25
$-92.7M
Q2 25
$-99.9M
Q1 25
$-95.2M
$-316.2M
Q4 24
$-111.0M
Q3 24
$-107.8M
Q2 24
$-102.6M
Q1 24
$-115.0M
Gross Margin
GH
GH
PCLA
PCLA
Q4 25
64.6%
Q3 25
64.7%
Q2 25
65.0%
Q1 25
63.3%
Q4 24
61.6%
Q3 24
61.1%
Q2 24
59.1%
Q1 24
61.2%
Operating Margin
GH
GH
PCLA
PCLA
Q4 25
-43.0%
Q3 25
-37.3%
Q2 25
-45.9%
Q1 25
-54.6%
-114.8%
Q4 24
-62.4%
Q3 24
-61.3%
Q2 24
-56.8%
Q1 24
-59.2%
Net Margin
GH
GH
PCLA
PCLA
Q4 25
-45.7%
Q3 25
-35.0%
Q2 25
-43.0%
Q1 25
-46.8%
-125.2%
Q4 24
-55.0%
Q3 24
-56.3%
Q2 24
-57.9%
Q1 24
-68.2%
EPS (diluted)
GH
GH
PCLA
PCLA
Q4 25
$-1.01
Q3 25
$-0.74
Q2 25
$-0.80
Q1 25
$-0.77
Q4 24
$-0.90
Q3 24
$-0.88
Q2 24
$-0.84
Q1 24
$-0.94

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GH
GH
PCLA
PCLA
Cash + ST InvestmentsLiquidity on hand
$378.2M
$456.8M
Total DebtLower is stronger
$1.5B
Stockholders' EquityBook value
$-99.3M
$354.8M
Total Assets
$2.0B
$1.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GH
GH
PCLA
PCLA
Q4 25
$378.2M
Q3 25
$580.0M
Q2 25
$629.1M
Q1 25
$698.6M
$456.8M
Q4 24
$525.5M
Q3 24
$585.0M
Q2 24
$933.7M
Q1 24
$1.0B
Total Debt
GH
GH
PCLA
PCLA
Q4 25
$1.5B
Q3 25
$1.1B
Q2 25
$1.1B
Q1 25
$1.1B
Q4 24
$1.1B
Q3 24
Q2 24
Q1 24
Stockholders' Equity
GH
GH
PCLA
PCLA
Q4 25
$-99.3M
Q3 25
$-354.5M
Q2 25
$-305.5M
Q1 25
$-250.8M
$354.8M
Q4 24
$-139.6M
Q3 24
$-60.1M
Q2 24
$-1.6M
Q1 24
$68.3M
Total Assets
GH
GH
PCLA
PCLA
Q4 25
$2.0B
Q3 25
$1.3B
Q2 25
$1.3B
Q1 25
$1.3B
$1.2B
Q4 24
$1.5B
Q3 24
$1.5B
Q2 24
$1.6B
Q1 24
$1.7B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GH
GH
PCLA
PCLA
Operating Cash FlowLast quarter
$-26.4M
$-245.6M
Free Cash FlowOCF − Capex
$-54.2M
$-256.6M
FCF MarginFCF / Revenue
-19.3%
-101.6%
Capex IntensityCapex / Revenue
9.9%
4.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-233.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GH
GH
PCLA
PCLA
Q4 25
$-26.4M
Q3 25
$-35.4M
Q2 25
$-60.3M
Q1 25
$-62.7M
$-245.6M
Q4 24
$-64.5M
Q3 24
$-51.1M
Q2 24
$-94.0M
Q1 24
$-30.3M
Free Cash Flow
GH
GH
PCLA
PCLA
Q4 25
$-54.2M
Q3 25
$-45.8M
Q2 25
$-65.9M
Q1 25
$-67.1M
$-256.6M
Q4 24
$-83.4M
Q3 24
$-55.3M
Q2 24
$-99.1M
Q1 24
$-37.2M
FCF Margin
GH
GH
PCLA
PCLA
Q4 25
-19.3%
Q3 25
-17.3%
Q2 25
-28.4%
Q1 25
-33.0%
-101.6%
Q4 24
-41.3%
Q3 24
-28.9%
Q2 24
-55.9%
Q1 24
-22.1%
Capex Intensity
GH
GH
PCLA
PCLA
Q4 25
9.9%
Q3 25
3.9%
Q2 25
2.4%
Q1 25
2.2%
4.3%
Q4 24
9.4%
Q3 24
2.2%
Q2 24
2.9%
Q1 24
4.1%

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GH
GH

Oncology$189.9M68%
Biopharma Data$54.0M19%
Screening$35.1M12%
Licensing Other$2.2M1%

PCLA
PCLA

Revenue from product$179.1M71%
Revenue from SaaS, Maintenance and others$42.4M17%
Revenue from product – related party$31.0M12%

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