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Side-by-side financial comparison of Gossamer Bio, Inc. (GOSS) and NexPoint Real Estate Finance, Inc. (NREF). Click either name above to swap in a different company.

Gossamer Bio, Inc. is the larger business by last-quarter revenue ($13.8M vs $11.1M, roughly 1.2× NexPoint Real Estate Finance, Inc.). NexPoint Real Estate Finance, Inc. runs the higher net margin — 216.6% vs -342.3%, a 559.0% gap on every dollar of revenue. On growth, Gossamer Bio, Inc. posted the faster year-over-year revenue change (47.1% vs -48.8%).

Gossamer Bio, Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing novel therapeutics for patients with serious immunology, inflammation and oncology conditions. It advances a pipeline of proprietary product candidates across multiple clinical phases, primarily serving healthcare markets in North America and other global regions.

NexPoint Real Estate Finance, Inc. is a US-based commercial real estate finance firm that offers structured financing solutions for multifamily, office, industrial, and hospitality properties. It focuses on originating, managing and servicing a diversified portfolio of mortgage loans and real estate-related investments to deliver stable risk-adjusted returns to stakeholders.

GOSS vs NREF — Head-to-Head

Bigger by revenue
GOSS
GOSS
1.2× larger
GOSS
$13.8M
$11.1M
NREF
Growing faster (revenue YoY)
GOSS
GOSS
+96.0% gap
GOSS
47.1%
-48.8%
NREF
Higher net margin
NREF
NREF
559.0% more per $
NREF
216.6%
-342.3%
GOSS

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GOSS
GOSS
NREF
NREF
Revenue
$13.8M
$11.1M
Net Profit
$-47.2M
$24.0M
Gross Margin
Operating Margin
-333.6%
Net Margin
-342.3%
216.6%
Revenue YoY
47.1%
-48.8%
Net Profit YoY
-43.0%
58.7%
EPS (diluted)
$-0.21
$0.47

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GOSS
GOSS
NREF
NREF
Q4 25
$13.8M
$11.1M
Q3 25
$13.3M
$12.5M
Q2 25
$12.1M
Q1 25
$11.5M
Q4 24
$21.7M
Q3 24
$12.5M
Q2 24
$95.8M
$6.7M
Q1 24
$0
$-12.8M
Net Profit
GOSS
GOSS
NREF
NREF
Q4 25
$-47.2M
$24.0M
Q3 25
$-48.2M
$50.9M
Q2 25
$22.3M
Q1 25
$26.0M
Q4 24
$15.2M
Q3 24
$23.3M
Q2 24
$49.2M
$12.1M
Q1 24
$-41.9M
$-14.6M
Operating Margin
GOSS
GOSS
NREF
NREF
Q4 25
-333.6%
Q3 25
-369.4%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
54.3%
Q1 24
Net Margin
GOSS
GOSS
NREF
NREF
Q4 25
-342.3%
216.6%
Q3 25
-362.7%
407.0%
Q2 25
184.5%
Q1 25
225.6%
Q4 24
69.9%
Q3 24
186.4%
Q2 24
51.4%
179.7%
Q1 24
114.3%
EPS (diluted)
GOSS
GOSS
NREF
NREF
Q4 25
$-0.21
$0.47
Q3 25
$-0.21
$1.14
Q2 25
$0.54
Q1 25
$0.70
Q4 24
$0.71
Q3 24
$0.74
Q2 24
$0.22
$0.40
Q1 24
$-0.19
$-0.83

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GOSS
GOSS
NREF
NREF
Cash + ST InvestmentsLiquidity on hand
$136.9M
$31.1M
Total DebtLower is stronger
$771.2M
Stockholders' EquityBook value
$-122.8M
$388.0M
Total Assets
$172.2M
$5.3B
Debt / EquityLower = less leverage
1.99×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GOSS
GOSS
NREF
NREF
Q4 25
$136.9M
$31.1M
Q3 25
$180.2M
$17.9M
Q2 25
$9.1M
Q1 25
$19.2M
Q4 24
$3.9M
Q3 24
$34.7M
Q2 24
$354.5M
$4.3M
Q1 24
$244.4M
$13.5M
Total Debt
GOSS
GOSS
NREF
NREF
Q4 25
$771.2M
Q3 25
$720.9M
Q2 25
$815.6M
Q1 25
$831.5M
Q4 24
$799.3M
Q3 24
$815.5M
Q2 24
$861.0M
Q1 24
$843.3M
Stockholders' Equity
GOSS
GOSS
NREF
NREF
Q4 25
$-122.8M
$388.0M
Q3 25
$-82.3M
$375.4M
Q2 25
$348.2M
Q1 25
$343.7M
Q4 24
$336.5M
Q3 24
$335.8M
Q2 24
$81.5M
$327.5M
Q1 24
$26.7M
$327.1M
Total Assets
GOSS
GOSS
NREF
NREF
Q4 25
$172.2M
$5.3B
Q3 25
$208.8M
$5.3B
Q2 25
$5.4B
Q1 25
$5.4B
Q4 24
$5.4B
Q3 24
$5.7B
Q2 24
$373.4M
$6.6B
Q1 24
$259.4M
$7.1B
Debt / Equity
GOSS
GOSS
NREF
NREF
Q4 25
1.99×
Q3 25
1.92×
Q2 25
2.34×
Q1 25
2.42×
Q4 24
2.38×
Q3 24
2.43×
Q2 24
2.63×
Q1 24
2.58×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GOSS
GOSS
NREF
NREF
Operating Cash FlowLast quarter
$-48.3M
$-4.5M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
-0.19×
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GOSS
GOSS
NREF
NREF
Q4 25
$-48.3M
$-4.5M
Q3 25
$-36.2M
$8.1M
Q2 25
$3.3M
Q1 25
$16.0M
Q4 24
$4.4M
Q3 24
$14.7M
Q2 24
$116.3M
$-7.5M
Q1 24
$-52.3M
$17.7M
Capex Intensity
GOSS
GOSS
NREF
NREF
Q4 25
0.0%
Q3 25
0.0%
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.0%
Q1 24
Cash Conversion
GOSS
GOSS
NREF
NREF
Q4 25
-0.19×
Q3 25
0.16×
Q2 25
0.15×
Q1 25
0.62×
Q4 24
0.29×
Q3 24
0.63×
Q2 24
2.36×
-0.62×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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