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Side-by-side financial comparison of GRAIL, Inc. (GRAL) and HEALTHSTREAM INC (HSTM). Click either name above to swap in a different company.

HEALTHSTREAM INC is the larger business by last-quarter revenue ($79.7M vs $43.6M, roughly 1.8× GRAIL, Inc.). On growth, GRAIL, Inc. posted the faster year-over-year revenue change (14.0% vs 7.4%). HEALTHSTREAM INC produced more free cash flow last quarter ($13.0M vs $-63.9M). Over the past eight quarters, GRAIL, Inc.'s revenue compounded faster (27.7% CAGR vs 4.7%).

GRAIL, Inc. is an American biotechnology company based in Menlo Park, California founded in 2015 seeking to develop an early cancer screening test for people who do not have symptoms. As a startup it was a subsidiary of Illumina, which bought it outright in 2021.

HealthStream Inc is a leading U.S.-based provider of workforce development, compliance, and training solutions tailored for the healthcare industry. It offers cloud-based platforms covering clinical skill training, talent management, patient safety education, and regulatory adherence tools, serving over 4,000 healthcare organizations including hospitals, clinics, and long-term care facilities nationwide.

GRAL vs HSTM — Head-to-Head

Bigger by revenue
HSTM
HSTM
1.8× larger
HSTM
$79.7M
$43.6M
GRAL
Growing faster (revenue YoY)
GRAL
GRAL
+6.6% gap
GRAL
14.0%
7.4%
HSTM
More free cash flow
HSTM
HSTM
$76.9M more FCF
HSTM
$13.0M
$-63.9M
GRAL
Faster 2-yr revenue CAGR
GRAL
GRAL
Annualised
GRAL
27.7%
4.7%
HSTM

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GRAL
GRAL
HSTM
HSTM
Revenue
$43.6M
$79.7M
Net Profit
$-99.2M
Gross Margin
Operating Margin
-285.4%
3.0%
Net Margin
-227.5%
Revenue YoY
14.0%
7.4%
Net Profit YoY
-2.2%
EPS (diluted)
$-2.37
$0.09

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GRAL
GRAL
HSTM
HSTM
Q4 25
$43.6M
$79.7M
Q3 25
$36.2M
$76.5M
Q2 25
$35.5M
$74.4M
Q1 25
$31.8M
$73.5M
Q4 24
$38.3M
$74.2M
Q3 24
$28.7M
$73.1M
Q2 24
$32.0M
$71.6M
Q1 24
$26.7M
$72.8M
Net Profit
GRAL
GRAL
HSTM
HSTM
Q4 25
$-99.2M
Q3 25
$-89.0M
$6.1M
Q2 25
$-114.0M
$5.4M
Q1 25
$-106.2M
$4.3M
Q4 24
$-97.1M
Q3 24
$-125.7M
$5.7M
Q2 24
$-1.6B
$4.2M
Q1 24
$-218.9M
$5.2M
Operating Margin
GRAL
GRAL
HSTM
HSTM
Q4 25
-285.4%
3.0%
Q3 25
-346.2%
9.9%
Q2 25
-446.9%
7.9%
Q1 25
-482.5%
6.0%
Q4 24
-358.0%
6.3%
Q3 24
-640.5%
8.9%
Q2 24
-5133.8%
6.2%
Q1 24
-851.1%
7.8%
Net Margin
GRAL
GRAL
HSTM
HSTM
Q4 25
-227.5%
Q3 25
-245.8%
8.0%
Q2 25
-320.7%
7.2%
Q1 25
-333.6%
5.9%
Q4 24
-253.8%
Q3 24
-438.7%
7.8%
Q2 24
-4958.8%
5.8%
Q1 24
-819.3%
7.2%
EPS (diluted)
GRAL
GRAL
HSTM
HSTM
Q4 25
$-2.37
$0.09
Q3 25
$-2.46
$0.20
Q2 25
$-3.18
$0.18
Q1 25
$-3.10
$0.14
Q4 24
$-1.49
$0.16
Q3 24
$-3.94
$0.19
Q2 24
$-51.06
$0.14
Q1 24
$-7.05
$0.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GRAL
GRAL
HSTM
HSTM
Cash + ST InvestmentsLiquidity on hand
$249.7M
$36.2M
Total DebtLower is stronger
Stockholders' EquityBook value
$2.6B
$354.0M
Total Assets
$2.9B
$520.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GRAL
GRAL
HSTM
HSTM
Q4 25
$249.7M
$36.2M
Q3 25
$126.9M
$53.5M
Q2 25
$127.4M
$52.1M
Q1 25
$133.9M
$77.3M
Q4 24
$214.2M
$59.5M
Q3 24
$853.6M
$57.5M
Q2 24
$958.8M
$46.1M
Q1 24
$199.7M
$52.4M
Stockholders' Equity
GRAL
GRAL
HSTM
HSTM
Q4 25
$2.6B
$354.0M
Q3 25
$2.2B
$349.2M
Q2 25
$2.3B
$350.6M
Q1 25
$2.4B
$362.8M
Q4 24
$2.5B
$359.4M
Q3 24
$2.6B
$355.5M
Q2 24
$2.7B
$349.2M
Q1 24
$344.9M
Total Assets
GRAL
GRAL
HSTM
HSTM
Q4 25
$2.9B
$520.4M
Q3 25
$2.6B
$499.9M
Q2 25
$2.7B
$500.1M
Q1 25
$2.8B
$524.0M
Q4 24
$3.0B
$510.8M
Q3 24
$3.1B
$502.8M
Q2 24
$3.3B
$499.6M
Q1 24
$511.6M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GRAL
GRAL
HSTM
HSTM
Operating Cash FlowLast quarter
$-63.8M
$13.2M
Free Cash FlowOCF − Capex
$-63.9M
$13.0M
FCF MarginFCF / Revenue
-146.5%
16.3%
Capex IntensityCapex / Revenue
0.2%
0.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-299.9M
$59.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GRAL
GRAL
HSTM
HSTM
Q4 25
$-63.8M
$13.2M
Q3 25
$-63.2M
$18.0M
Q2 25
$-77.0M
$5.0M
Q1 25
$-95.0M
$27.1M
Q4 24
$11.2M
Q3 24
$-104.6M
$19.1M
Q2 24
$-171.8M
$6.5M
Q1 24
$-207.3M
$20.9M
Free Cash Flow
GRAL
GRAL
HSTM
HSTM
Q4 25
$-63.9M
$13.0M
Q3 25
$-63.6M
$17.9M
Q2 25
$-77.3M
$2.7M
Q1 25
$-95.1M
$26.0M
Q4 24
$11.0M
Q3 24
$-105.6M
$18.8M
Q2 24
$-173.2M
$6.3M
Q1 24
$-209.8M
$20.2M
FCF Margin
GRAL
GRAL
HSTM
HSTM
Q4 25
-146.5%
16.3%
Q3 25
-175.8%
23.4%
Q2 25
-217.6%
3.6%
Q1 25
-298.6%
35.4%
Q4 24
14.8%
Q3 24
-368.4%
25.8%
Q2 24
-541.7%
8.8%
Q1 24
-785.3%
27.8%
Capex Intensity
GRAL
GRAL
HSTM
HSTM
Q4 25
0.2%
0.3%
Q3 25
1.1%
0.1%
Q2 25
1.0%
3.1%
Q1 25
0.2%
1.4%
Q4 24
0.3%
Q3 24
3.4%
0.4%
Q2 24
4.3%
0.2%
Q1 24
9.5%
1.0%
Cash Conversion
GRAL
GRAL
HSTM
HSTM
Q4 25
Q3 25
2.96×
Q2 25
0.93×
Q1 25
6.25×
Q4 24
Q3 24
3.34×
Q2 24
1.55×
Q1 24
4.01×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GRAL
GRAL

Screening Revenue$42.3M97%
Developmental Services Revenue$1.3M3%

HSTM
HSTM

Subscription Services$77.0M97%
Professional Services$2.7M3%

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