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Side-by-side financial comparison of GRAIL, Inc. (GRAL) and MEDIFAST INC (MED). Click either name above to swap in a different company.

MEDIFAST INC is the larger business by last-quarter revenue ($75.1M vs $43.6M, roughly 1.7× GRAIL, Inc.). On growth, GRAIL, Inc. posted the faster year-over-year revenue change (14.0% vs -36.9%). MEDIFAST INC produced more free cash flow last quarter ($-6.6M vs $-63.9M). Over the past eight quarters, GRAIL, Inc.'s revenue compounded faster (27.7% CAGR vs -34.4%).

GRAIL, Inc. is an American biotechnology company based in Menlo Park, California founded in 2015 seeking to develop an early cancer screening test for people who do not have symptoms. As a startup it was a subsidiary of Illumina, which bought it outright in 2021.

Medifast, Inc. is an American nutrition and weight loss company based in Baltimore, Maryland. Medifast produces, distributes, and sells weight loss and health-related products through websites, multi-level marketing, telemarketing, and franchised weight loss clinics.

GRAL vs MED — Head-to-Head

Bigger by revenue
MED
MED
1.7× larger
MED
$75.1M
$43.6M
GRAL
Growing faster (revenue YoY)
GRAL
GRAL
+50.9% gap
GRAL
14.0%
-36.9%
MED
More free cash flow
MED
MED
$57.3M more FCF
MED
$-6.6M
$-63.9M
GRAL
Faster 2-yr revenue CAGR
GRAL
GRAL
Annualised
GRAL
27.7%
-34.4%
MED

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
GRAL
GRAL
MED
MED
Revenue
$43.6M
$75.1M
Net Profit
$-99.2M
Gross Margin
69.4%
Operating Margin
-285.4%
-10.4%
Net Margin
-227.5%
Revenue YoY
14.0%
-36.9%
Net Profit YoY
-2.2%
EPS (diluted)
$-2.37
$-1.64

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
GRAL
GRAL
MED
MED
Q4 25
$43.6M
$75.1M
Q3 25
$36.2M
$89.4M
Q2 25
$35.5M
$105.6M
Q1 25
$31.8M
$115.7M
Q4 24
$38.3M
$119.0M
Q3 24
$28.7M
$140.2M
Q2 24
$32.0M
$168.6M
Q1 24
$26.7M
$174.7M
Net Profit
GRAL
GRAL
MED
MED
Q4 25
$-99.2M
Q3 25
$-89.0M
$-2.3M
Q2 25
$-114.0M
$2.5M
Q1 25
$-106.2M
$-772.0K
Q4 24
$-97.1M
Q3 24
$-125.7M
$1.1M
Q2 24
$-1.6B
$-8.2M
Q1 24
$-218.9M
$8.3M
Gross Margin
GRAL
GRAL
MED
MED
Q4 25
69.4%
Q3 25
69.5%
Q2 25
72.6%
Q1 25
72.8%
Q4 24
74.1%
Q3 24
75.4%
Q2 24
73.2%
Q1 24
72.8%
Operating Margin
GRAL
GRAL
MED
MED
Q4 25
-285.4%
-10.4%
Q3 25
-346.2%
-4.6%
Q2 25
-446.9%
-1.0%
Q1 25
-482.5%
-1.1%
Q4 24
-358.0%
0.6%
Q3 24
-640.5%
1.5%
Q2 24
-5133.8%
-4.7%
Q1 24
-851.1%
4.5%
Net Margin
GRAL
GRAL
MED
MED
Q4 25
-227.5%
Q3 25
-245.8%
-2.5%
Q2 25
-320.7%
2.3%
Q1 25
-333.6%
-0.7%
Q4 24
-253.8%
Q3 24
-438.7%
0.8%
Q2 24
-4958.8%
-4.8%
Q1 24
-819.3%
4.8%
EPS (diluted)
GRAL
GRAL
MED
MED
Q4 25
$-2.37
$-1.64
Q3 25
$-2.46
$-0.21
Q2 25
$-3.18
$0.22
Q1 25
$-3.10
$-0.07
Q4 24
$-1.49
$0.08
Q3 24
$-3.94
$0.10
Q2 24
$-51.06
$-0.75
Q1 24
$-7.05
$0.76

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
GRAL
GRAL
MED
MED
Cash + ST InvestmentsLiquidity on hand
$249.7M
$167.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$2.6B
$198.9M
Total Assets
$2.9B
$248.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
GRAL
GRAL
MED
MED
Q4 25
$249.7M
$167.3M
Q3 25
$126.9M
$173.5M
Q2 25
$127.4M
$162.7M
Q1 25
$133.9M
$164.6M
Q4 24
$214.2M
$162.3M
Q3 24
$853.6M
$170.0M
Q2 24
$958.8M
$163.5M
Q1 24
$199.7M
$156.4M
Stockholders' Equity
GRAL
GRAL
MED
MED
Q4 25
$2.6B
$198.9M
Q3 25
$2.2B
$214.7M
Q2 25
$2.3B
$216.0M
Q1 25
$2.4B
$211.0M
Q4 24
$2.5B
$210.1M
Q3 24
$2.6B
$207.3M
Q2 24
$2.7B
$205.3M
Q1 24
$211.0M
Total Assets
GRAL
GRAL
MED
MED
Q4 25
$2.9B
$248.0M
Q3 25
$2.6B
$268.2M
Q2 25
$2.7B
$269.3M
Q1 25
$2.8B
$280.0M
Q4 24
$3.0B
$284.2M
Q3 24
$3.1B
$291.2M
Q2 24
$3.3B
$293.5M
Q1 24
$302.8M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
GRAL
GRAL
MED
MED
Operating Cash FlowLast quarter
$-63.8M
$-5.3M
Free Cash FlowOCF − Capex
$-63.9M
$-6.6M
FCF MarginFCF / Revenue
-146.5%
-8.8%
Capex IntensityCapex / Revenue
0.2%
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-299.9M
$1.2M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
GRAL
GRAL
MED
MED
Q4 25
$-63.8M
$-5.3M
Q3 25
$-63.2M
$12.1M
Q2 25
$-77.0M
$-3.4M
Q1 25
$-95.0M
$3.4M
Q4 24
$-4.9M
Q3 24
$-104.6M
$9.1M
Q2 24
$-171.8M
$13.1M
Q1 24
$-207.3M
$7.3M
Free Cash Flow
GRAL
GRAL
MED
MED
Q4 25
$-63.9M
$-6.6M
Q3 25
$-63.6M
$10.8M
Q2 25
$-77.3M
$-4.8M
Q1 25
$-95.1M
$1.9M
Q4 24
$-7.2M
Q3 24
$-105.6M
$7.7M
Q2 24
$-173.2M
$11.1M
Q1 24
$-209.8M
$5.4M
FCF Margin
GRAL
GRAL
MED
MED
Q4 25
-146.5%
-8.8%
Q3 25
-175.8%
12.0%
Q2 25
-217.6%
-4.5%
Q1 25
-298.6%
1.6%
Q4 24
-6.1%
Q3 24
-368.4%
5.5%
Q2 24
-541.7%
6.6%
Q1 24
-785.3%
3.1%
Capex Intensity
GRAL
GRAL
MED
MED
Q4 25
0.2%
1.8%
Q3 25
1.1%
1.5%
Q2 25
1.0%
1.3%
Q1 25
0.2%
1.3%
Q4 24
1.9%
Q3 24
3.4%
1.0%
Q2 24
4.3%
1.1%
Q1 24
9.5%
1.1%
Cash Conversion
GRAL
GRAL
MED
MED
Q4 25
Q3 25
Q2 25
-1.36×
Q1 25
Q4 24
Q3 24
8.04×
Q2 24
Q1 24
0.88×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

GRAL
GRAL

Screening Revenue$42.3M97%
Developmental Services Revenue$1.3M3%

MED
MED

Segment breakdown not available.

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