vs
Side-by-side financial comparison of GRAIL, Inc. (GRAL) and Orchid Island Capital, Inc. (ORC). Click either name above to swap in a different company.
GRAIL, Inc. is the larger business by last-quarter revenue ($43.6M vs $38.5M, roughly 1.1× Orchid Island Capital, Inc.). Orchid Island Capital, Inc. runs the higher net margin — 268.7% vs -227.5%, a 496.2% gap on every dollar of revenue. On growth, Orchid Island Capital, Inc. posted the faster year-over-year revenue change (372.6% vs 14.0%). Over the past eight quarters, Orchid Island Capital, Inc.'s revenue compounded faster (301.6% CAGR vs 27.7%).
GRAIL, Inc. is an American biotechnology company based in Menlo Park, California founded in 2015 seeking to develop an early cancer screening test for people who do not have symptoms. As a startup it was a subsidiary of Illumina, which bought it outright in 2021.
Orchid Island Capital, Inc. is a U.S.-based specialty finance company operating as a real estate investment trust. It primarily invests in residential mortgage-backed securities, including agency and non-agency products, targeting consistent risk-adjusted returns for its investors across U.S. fixed income markets.
GRAL vs ORC — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $43.6M | $38.5M |
| Net Profit | $-99.2M | $103.4M |
| Gross Margin | — | — |
| Operating Margin | -285.4% | — |
| Net Margin | -227.5% | 268.7% |
| Revenue YoY | 14.0% | 372.6% |
| Net Profit YoY | -2.2% | 1764.9% |
| EPS (diluted) | $-2.37 | — |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $43.6M | $38.5M | ||
| Q3 25 | $36.2M | $26.9M | ||
| Q2 25 | $35.5M | $23.2M | ||
| Q1 25 | $31.8M | $19.7M | ||
| Q4 24 | $38.3M | — | ||
| Q3 24 | $28.7M | $340.0K | ||
| Q2 24 | $32.0M | $-697.0K | ||
| Q1 24 | $26.7M | $-2.5M |
| Q4 25 | $-99.2M | $103.4M | ||
| Q3 25 | $-89.0M | $72.1M | ||
| Q2 25 | $-114.0M | $-33.6M | ||
| Q1 25 | $-106.2M | $17.1M | ||
| Q4 24 | $-97.1M | — | ||
| Q3 24 | $-125.7M | $17.3M | ||
| Q2 24 | $-1.6B | $-5.0M | ||
| Q1 24 | $-218.9M | $19.8M |
| Q4 25 | -285.4% | — | ||
| Q3 25 | -346.2% | — | ||
| Q2 25 | -446.9% | — | ||
| Q1 25 | -482.5% | — | ||
| Q4 24 | -358.0% | — | ||
| Q3 24 | -640.5% | — | ||
| Q2 24 | -5133.8% | — | ||
| Q1 24 | -851.1% | — |
| Q4 25 | -227.5% | 268.7% | ||
| Q3 25 | -245.8% | 267.8% | ||
| Q2 25 | -320.7% | -145.0% | ||
| Q1 25 | -333.6% | 86.9% | ||
| Q4 24 | -253.8% | — | ||
| Q3 24 | -438.7% | 5094.1% | ||
| Q2 24 | -4958.8% | 714.3% | ||
| Q1 24 | -819.3% | -794.2% |
| Q4 25 | $-2.37 | — | ||
| Q3 25 | $-2.46 | — | ||
| Q2 25 | $-3.18 | — | ||
| Q1 25 | $-3.10 | — | ||
| Q4 24 | $-1.49 | — | ||
| Q3 24 | $-3.94 | — | ||
| Q2 24 | $-51.06 | — | ||
| Q1 24 | $-7.05 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $249.7M | $665.9M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $2.6B | $1.4B |
| Total Assets | $2.9B | $11.7B |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $249.7M | $665.9M | ||
| Q3 25 | $126.9M | $583.9M | ||
| Q2 25 | $127.4M | $440.8M | ||
| Q1 25 | $133.9M | $396.4M | ||
| Q4 24 | $214.2M | — | ||
| Q3 24 | $853.6M | $322.1M | ||
| Q2 24 | $958.8M | $241.0M | ||
| Q1 24 | $199.7M | $190.4M |
| Q4 25 | $2.6B | $1.4B | ||
| Q3 25 | $2.2B | $1.1B | ||
| Q2 25 | $2.3B | $912.0M | ||
| Q1 25 | $2.4B | $855.9M | ||
| Q4 24 | $2.5B | — | ||
| Q3 24 | $2.6B | $656.0M | ||
| Q2 24 | $2.7B | $555.9M | ||
| Q1 24 | — | $481.6M |
| Q4 25 | $2.9B | $11.7B | ||
| Q3 25 | $2.6B | $9.1B | ||
| Q2 25 | $2.7B | $7.6B | ||
| Q1 25 | $2.8B | $7.3B | ||
| Q4 24 | $3.0B | — | ||
| Q3 24 | $3.1B | $5.9B | ||
| Q2 24 | $3.3B | $4.9B | ||
| Q1 24 | — | $4.2B |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-63.8M | $120.4M |
| Free Cash FlowOCF − Capex | $-63.9M | — |
| FCF MarginFCF / Revenue | -146.5% | — |
| Capex IntensityCapex / Revenue | 0.2% | — |
| Cash ConversionOCF / Net Profit | — | 1.16× |
| TTM Free Cash FlowTrailing 4 quarters | $-299.9M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-63.8M | $120.4M | ||
| Q3 25 | $-63.2M | $28.0M | ||
| Q2 25 | $-77.0M | $18.4M | ||
| Q1 25 | $-95.0M | $25.8M | ||
| Q4 24 | — | — | ||
| Q3 24 | $-104.6M | $-14.8M | ||
| Q2 24 | $-171.8M | $19.3M | ||
| Q1 24 | $-207.3M | $45.0M |
| Q4 25 | $-63.9M | — | ||
| Q3 25 | $-63.6M | — | ||
| Q2 25 | $-77.3M | — | ||
| Q1 25 | $-95.1M | — | ||
| Q4 24 | — | — | ||
| Q3 24 | $-105.6M | — | ||
| Q2 24 | $-173.2M | — | ||
| Q1 24 | $-209.8M | — |
| Q4 25 | -146.5% | — | ||
| Q3 25 | -175.8% | — | ||
| Q2 25 | -217.6% | — | ||
| Q1 25 | -298.6% | — | ||
| Q4 24 | — | — | ||
| Q3 24 | -368.4% | — | ||
| Q2 24 | -541.7% | — | ||
| Q1 24 | -785.3% | — |
| Q4 25 | 0.2% | — | ||
| Q3 25 | 1.1% | — | ||
| Q2 25 | 1.0% | — | ||
| Q1 25 | 0.2% | — | ||
| Q4 24 | — | — | ||
| Q3 24 | 3.4% | — | ||
| Q2 24 | 4.3% | — | ||
| Q1 24 | 9.5% | — |
| Q4 25 | — | 1.16× | ||
| Q3 25 | — | 0.39× | ||
| Q2 25 | — | — | ||
| Q1 25 | — | 1.51× | ||
| Q4 24 | — | — | ||
| Q3 24 | — | -0.86× | ||
| Q2 24 | — | — | ||
| Q1 24 | — | 2.28× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
GRAL
| Screening Revenue | $42.3M | 97% |
| Developmental Services Revenue | $1.3M | 3% |
ORC
Segment breakdown not available.
