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Side-by-side financial comparison of HALOZYME THERAPEUTICS, INC. (HALO) and PROSPERITY BANCSHARES INC (PB). Click either name above to swap in a different company.
HALOZYME THERAPEUTICS, INC. is the larger business by last-quarter revenue ($451.8M vs $367.6M, roughly 1.2× PROSPERITY BANCSHARES INC). PROSPERITY BANCSHARES INC runs the higher net margin — 31.6% vs -31.3%, a 63.0% gap on every dollar of revenue. Over the past eight quarters, HALOZYME THERAPEUTICS, INC.'s revenue compounded faster (51.9% CAGR vs 19.2%).
Halozyme Therapeutics, Inc. is an American biotechnology company. It develops oncology therapies designed to target the tumor microenvironment.
Prosperity Bancshares, Inc. is a bank holding company headquartered in Houston, Texas with operations in Texas and central Oklahoma. As of December 31, 2019, the company operated 285 branches: 65 in the Houston area, including The Woodlands, Texas; 30 in South Texas, including Corpus Christi, Texas and Victoria, Texas; 75 in the Dallas–Fort Worth metroplex; 22 in East Texas; 29 in Central Texas, including Austin, Texas and San Antonio; 34 in West Texas, including Lubbock, Texas, Midland–Odess...
HALO vs PB — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $451.8M | $367.6M |
| Net Profit | $-141.6M | $116.3M |
| Gross Margin | 82.6% | — |
| Operating Margin | -20.6% | — |
| Net Margin | -31.3% | 31.6% |
| Revenue YoY | 51.6% | — |
| Net Profit YoY | -203.3% | -10.7% |
| EPS (diluted) | $-1.13 | $1.16 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $367.6M | ||
| Q4 25 | $451.8M | $275.0M | ||
| Q3 25 | $354.3M | $273.4M | ||
| Q2 25 | $325.7M | $267.7M | ||
| Q1 25 | $264.9M | $265.4M | ||
| Q4 24 | $298.0M | $267.8M | ||
| Q3 24 | $290.1M | $261.7M | ||
| Q2 24 | $231.4M | $258.8M |
| Q1 26 | — | $116.3M | ||
| Q4 25 | $-141.6M | $139.9M | ||
| Q3 25 | $175.2M | $137.6M | ||
| Q2 25 | $165.2M | $135.2M | ||
| Q1 25 | $118.1M | $130.2M | ||
| Q4 24 | $137.0M | $130.1M | ||
| Q3 24 | $137.0M | $127.3M | ||
| Q2 24 | $93.2M | $111.6M |
| Q1 26 | — | — | ||
| Q4 25 | 82.6% | — | ||
| Q3 25 | 84.4% | — | ||
| Q2 25 | 85.8% | — | ||
| Q1 25 | 81.7% | — | ||
| Q4 24 | 85.9% | — | ||
| Q3 24 | 83.0% | — | ||
| Q2 24 | 82.9% | — |
| Q1 26 | — | — | ||
| Q4 25 | -20.6% | 65.1% | ||
| Q3 25 | 61.5% | 64.4% | ||
| Q2 25 | 62.2% | 64.3% | ||
| Q1 25 | 53.4% | 62.7% | ||
| Q4 24 | 58.9% | 62.0% | ||
| Q3 24 | 56.3% | 62.1% | ||
| Q2 24 | 50.7% | 55.2% |
| Q1 26 | — | 31.6% | ||
| Q4 25 | -31.3% | 50.9% | ||
| Q3 25 | 49.5% | 50.3% | ||
| Q2 25 | 50.7% | 50.5% | ||
| Q1 25 | 44.6% | 49.1% | ||
| Q4 24 | 46.0% | 48.6% | ||
| Q3 24 | 47.2% | 48.6% | ||
| Q2 24 | 40.3% | 43.1% |
| Q1 26 | — | $1.16 | ||
| Q4 25 | $-1.13 | $1.48 | ||
| Q3 25 | $1.43 | $1.45 | ||
| Q2 25 | $1.33 | $1.42 | ||
| Q1 25 | $0.93 | $1.37 | ||
| Q4 24 | $1.06 | $1.36 | ||
| Q3 24 | $1.05 | $1.34 | ||
| Q2 24 | $0.72 | $1.17 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $133.8M | — |
| Total DebtLower is stronger | $2.1B | — |
| Stockholders' EquityBook value | $48.8M | $8.2B |
| Total Assets | $2.5B | $43.6B |
| Debt / EquityLower = less leverage | 43.89× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $133.8M | — | ||
| Q3 25 | $419.7M | — | ||
| Q2 25 | $61.9M | — | ||
| Q1 25 | $176.3M | — | ||
| Q4 24 | $115.8M | — | ||
| Q3 24 | $154.3M | — | ||
| Q2 24 | $187.9M | — |
| Q1 26 | — | — | ||
| Q4 25 | $2.1B | — | ||
| Q3 25 | $1.5B | — | ||
| Q2 25 | $1.5B | — | ||
| Q1 25 | $1.5B | — | ||
| Q4 24 | $1.5B | — | ||
| Q3 24 | $1.5B | — | ||
| Q2 24 | $1.5B | — |
| Q1 26 | — | $8.2B | ||
| Q4 25 | $48.8M | $7.6B | ||
| Q3 25 | $503.9M | $7.7B | ||
| Q2 25 | $332.7M | $7.6B | ||
| Q1 25 | $482.3M | $7.5B | ||
| Q4 24 | $363.8M | $7.4B | ||
| Q3 24 | $452.7M | $7.4B | ||
| Q2 24 | $289.4M | $7.3B |
| Q1 26 | — | $43.6B | ||
| Q4 25 | $2.5B | $38.5B | ||
| Q3 25 | $2.2B | $38.3B | ||
| Q2 25 | $2.1B | $38.4B | ||
| Q1 25 | $2.2B | $38.8B | ||
| Q4 24 | $2.1B | $39.6B | ||
| Q3 24 | $2.1B | $40.1B | ||
| Q2 24 | $2.0B | $39.8B |
| Q1 26 | — | — | ||
| Q4 25 | 43.89× | — | ||
| Q3 25 | 3.00× | — | ||
| Q2 25 | 4.54× | — | ||
| Q1 25 | 3.13× | — | ||
| Q4 24 | 4.14× | — | ||
| Q3 24 | 3.32× | — | ||
| Q2 24 | 5.19× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $219.0M | — |
| Free Cash FlowOCF − Capex | $217.6M | — |
| FCF MarginFCF / Revenue | 48.2% | — |
| Capex IntensityCapex / Revenue | 0.3% | — |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $644.6M | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $219.0M | $78.3M | ||
| Q3 25 | $178.6M | $194.8M | ||
| Q2 25 | $99.7M | $98.2M | ||
| Q1 25 | $154.2M | $178.2M | ||
| Q4 24 | $178.5M | $-205.8M | ||
| Q3 24 | $115.4M | $274.6M | ||
| Q2 24 | $55.8M | $216.5M |
| Q1 26 | — | — | ||
| Q4 25 | $217.6M | $68.5M | ||
| Q3 25 | $175.6M | $185.7M | ||
| Q2 25 | $98.1M | $91.8M | ||
| Q1 25 | $153.3M | $171.1M | ||
| Q4 24 | $175.4M | $-210.7M | ||
| Q3 24 | $113.9M | $270.2M | ||
| Q2 24 | $53.2M | $211.8M |
| Q1 26 | — | — | ||
| Q4 25 | 48.2% | 24.9% | ||
| Q3 25 | 49.6% | 67.9% | ||
| Q2 25 | 30.1% | 34.3% | ||
| Q1 25 | 57.9% | 64.5% | ||
| Q4 24 | 58.9% | -78.7% | ||
| Q3 24 | 39.3% | 103.3% | ||
| Q2 24 | 23.0% | 81.8% |
| Q1 26 | — | — | ||
| Q4 25 | 0.3% | 3.6% | ||
| Q3 25 | 0.9% | 3.3% | ||
| Q2 25 | 0.5% | 2.4% | ||
| Q1 25 | 0.4% | 2.7% | ||
| Q4 24 | 1.0% | 1.8% | ||
| Q3 24 | 0.5% | 1.7% | ||
| Q2 24 | 1.1% | 1.8% |
| Q1 26 | — | — | ||
| Q4 25 | — | 0.56× | ||
| Q3 25 | 1.02× | 1.42× | ||
| Q2 25 | 0.60× | 0.73× | ||
| Q1 25 | 1.31× | 1.37× | ||
| Q4 24 | 1.30× | -1.58× | ||
| Q3 24 | 0.84× | 2.16× | ||
| Q2 24 | 0.60× | 1.94× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
HALO
| Royalty | $258.0M | 57% |
| Products | $122.7M | 27% |
| Proprietary Products Sales | $59.6M | 13% |
| Device Partnered Products | $12.9M | 3% |
PB
| Net Interest Income | $321.1M | 87% |
| Noninterest Income | $46.5M | 13% |
