vs

Side-by-side financial comparison of Harmony Biosciences Holdings, Inc. (HRMY) and Grand Canyon Education, Inc. (LOPE). Click either name above to swap in a different company.

Grand Canyon Education, Inc. is the larger business by last-quarter revenue ($308.1M vs $243.8M, roughly 1.3× Harmony Biosciences Holdings, Inc.). Grand Canyon Education, Inc. runs the higher net margin — 28.1% vs 9.2%, a 18.9% gap on every dollar of revenue. On growth, Harmony Biosciences Holdings, Inc. posted the faster year-over-year revenue change (21.1% vs 5.3%). Harmony Biosciences Holdings, Inc. produced more free cash flow last quarter ($126.0M vs $122.9M). Over the past eight quarters, Harmony Biosciences Holdings, Inc.'s revenue compounded faster (25.6% CAGR vs 5.9%).

Harmony Biosciences Holdings, Inc. is a commercial-stage biopharmaceutical company focused on developing and commercializing innovative therapies for rare neurological and central nervous system disorders. Its primary market is the United States, with its core product serving patients living with narcolepsy and other sleep-related CNS conditions across adult and pediatric segments.

Grand Canyon Education, Inc. (GCE) is an American for-profit corporation that provides services to universities, specializing in program development, online education, and operational support. Formerly affiliated with Grand Canyon University (GCU), a Christian university in Arizona, GCE became a separate publicly traded company in 2008.

HRMY vs LOPE — Head-to-Head

Bigger by revenue
LOPE
LOPE
1.3× larger
LOPE
$308.1M
$243.8M
HRMY
Growing faster (revenue YoY)
HRMY
HRMY
+15.8% gap
HRMY
21.1%
5.3%
LOPE
Higher net margin
LOPE
LOPE
18.9% more per $
LOPE
28.1%
9.2%
HRMY
More free cash flow
HRMY
HRMY
$3.2M more FCF
HRMY
$126.0M
$122.9M
LOPE
Faster 2-yr revenue CAGR
HRMY
HRMY
Annualised
HRMY
25.6%
5.9%
LOPE

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
HRMY
HRMY
LOPE
LOPE
Revenue
$243.8M
$308.1M
Net Profit
$22.5M
$86.7M
Gross Margin
71.9%
Operating Margin
15.8%
35.1%
Net Margin
9.2%
28.1%
Revenue YoY
21.1%
5.3%
Net Profit YoY
-54.6%
5.9%
EPS (diluted)
$0.38
$3.13

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
HRMY
HRMY
LOPE
LOPE
Q4 25
$243.8M
$308.1M
Q3 25
$239.5M
$261.1M
Q2 25
$200.5M
$247.5M
Q1 25
$184.7M
$289.3M
Q4 24
$201.3M
$292.6M
Q3 24
$186.0M
$238.3M
Q2 24
$172.8M
$227.5M
Q1 24
$154.6M
$274.7M
Net Profit
HRMY
HRMY
LOPE
LOPE
Q4 25
$22.5M
$86.7M
Q3 25
$50.9M
$16.3M
Q2 25
$39.8M
$41.5M
Q1 25
$45.6M
$71.6M
Q4 24
$49.5M
$81.9M
Q3 24
$46.1M
$41.5M
Q2 24
$11.6M
$34.9M
Q1 24
$38.3M
$68.0M
Gross Margin
HRMY
HRMY
LOPE
LOPE
Q4 25
71.9%
Q3 25
75.1%
Q2 25
81.0%
Q1 25
82.7%
Q4 24
73.0%
Q3 24
77.0%
Q2 24
81.4%
Q1 24
82.2%
Operating Margin
HRMY
HRMY
LOPE
LOPE
Q4 25
15.8%
35.1%
Q3 25
27.3%
6.9%
Q2 25
24.0%
20.9%
Q1 25
30.4%
30.4%
Q4 24
27.7%
34.2%
Q3 24
33.2%
20.2%
Q2 24
12.4%
18.8%
Q1 24
33.7%
30.8%
Net Margin
HRMY
HRMY
LOPE
LOPE
Q4 25
9.2%
28.1%
Q3 25
21.2%
6.2%
Q2 25
19.8%
16.8%
Q1 25
24.7%
24.8%
Q4 24
24.6%
28.0%
Q3 24
24.8%
17.4%
Q2 24
6.7%
15.3%
Q1 24
24.8%
24.8%
EPS (diluted)
HRMY
HRMY
LOPE
LOPE
Q4 25
$0.38
$3.13
Q3 25
$0.87
$0.58
Q2 25
$0.68
$1.48
Q1 25
$0.78
$2.52
Q4 24
$0.85
$2.83
Q3 24
$0.79
$1.42
Q2 24
$0.20
$1.19
Q1 24
$0.67
$2.29

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
HRMY
HRMY
LOPE
LOPE
Cash + ST InvestmentsLiquidity on hand
$775.3M
$111.8M
Total DebtLower is stronger
$163.7M
Stockholders' EquityBook value
$870.2M
$746.9M
Total Assets
$1.3B
$992.3M
Debt / EquityLower = less leverage
0.19×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
HRMY
HRMY
LOPE
LOPE
Q4 25
$775.3M
$111.8M
Q3 25
$672.6M
$97.3M
Q2 25
$565.3M
$192.3M
Q1 25
$507.0M
$144.5M
Q4 24
$467.2M
$324.6M
Q3 24
$410.5M
$263.6M
Q2 24
$346.9M
$241.3M
Q1 24
$372.4M
$196.2M
Total Debt
HRMY
HRMY
LOPE
LOPE
Q4 25
$163.7M
Q3 25
$168.5M
Q2 25
$172.1M
Q1 25
$175.7M
Q4 24
$179.3M
Q3 24
$182.8M
Q2 24
$186.4M
Q1 24
$190.0M
Stockholders' Equity
HRMY
HRMY
LOPE
LOPE
Q4 25
$870.2M
$746.9M
Q3 25
$835.1M
$758.0M
Q2 25
$773.1M
$778.0M
Q1 25
$720.5M
$780.7M
Q4 24
$659.2M
$783.9M
Q3 24
$596.8M
$764.1M
Q2 24
$538.6M
$759.2M
Q1 24
$515.4M
$759.4M
Total Assets
HRMY
HRMY
LOPE
LOPE
Q4 25
$1.3B
$992.3M
Q3 25
$1.2B
$1.0B
Q2 25
$1.1B
$1.0B
Q1 25
$1.1B
$1.0B
Q4 24
$999.2M
$1.0B
Q3 24
$928.1M
$992.9M
Q2 24
$858.4M
$992.7M
Q1 24
$847.0M
$1.0B
Debt / Equity
HRMY
HRMY
LOPE
LOPE
Q4 25
0.19×
Q3 25
0.20×
Q2 25
0.22×
Q1 25
0.24×
Q4 24
0.27×
Q3 24
0.31×
Q2 24
0.35×
Q1 24
0.37×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
HRMY
HRMY
LOPE
LOPE
Operating Cash FlowLast quarter
$126.2M
$130.5M
Free Cash FlowOCF − Capex
$126.0M
$122.9M
FCF MarginFCF / Revenue
51.7%
39.9%
Capex IntensityCapex / Revenue
0.0%
2.5%
Cash ConversionOCF / Net Profit
5.61×
1.50×
TTM Free Cash FlowTrailing 4 quarters
$347.9M
$238.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
HRMY
HRMY
LOPE
LOPE
Q4 25
$126.2M
$130.5M
Q3 25
$108.7M
$-48.6M
Q2 25
$79.3M
$124.0M
Q1 25
$34.0M
$67.6M
Q4 24
$75.6M
$135.8M
Q3 24
$70.5M
$-29.4M
Q2 24
$42.6M
$98.6M
Q1 24
$31.1M
$85.0M
Free Cash Flow
HRMY
HRMY
LOPE
LOPE
Q4 25
$126.0M
$122.9M
Q3 25
$108.7M
$-58.3M
Q2 25
$79.3M
$115.4M
Q1 25
$33.9M
$58.7M
Q4 24
$75.0M
$126.1M
Q3 24
$70.5M
$-39.0M
Q2 24
$42.0M
$89.6M
Q1 24
$31.1M
$76.0M
FCF Margin
HRMY
HRMY
LOPE
LOPE
Q4 25
51.7%
39.9%
Q3 25
45.4%
-22.3%
Q2 25
39.6%
46.6%
Q1 25
18.3%
20.3%
Q4 24
37.3%
43.1%
Q3 24
37.9%
-16.3%
Q2 24
24.3%
39.4%
Q1 24
20.1%
27.7%
Capex Intensity
HRMY
HRMY
LOPE
LOPE
Q4 25
0.0%
2.5%
Q3 25
0.0%
3.7%
Q2 25
0.0%
3.5%
Q1 25
0.1%
3.1%
Q4 24
0.3%
3.3%
Q3 24
0.0%
4.0%
Q2 24
0.4%
3.9%
Q1 24
0.0%
3.3%
Cash Conversion
HRMY
HRMY
LOPE
LOPE
Q4 25
5.61×
1.50×
Q3 25
2.14×
-2.99×
Q2 25
1.99×
2.98×
Q1 25
0.75×
0.94×
Q4 24
1.53×
1.66×
Q3 24
1.53×
-0.71×
Q2 24
3.68×
2.83×
Q1 24
0.81×
1.25×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Related Comparisons