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Side-by-side financial comparison of Harmony Biosciences Holdings, Inc. (HRMY) and PROSPERITY BANCSHARES INC (PB). Click either name above to swap in a different company.
PROSPERITY BANCSHARES INC is the larger business by last-quarter revenue ($367.6M vs $243.8M, roughly 1.5× Harmony Biosciences Holdings, Inc.). PROSPERITY BANCSHARES INC runs the higher net margin — 31.6% vs 9.2%, a 22.4% gap on every dollar of revenue. Over the past eight quarters, Harmony Biosciences Holdings, Inc.'s revenue compounded faster (25.6% CAGR vs 19.2%).
Harmony Biosciences Holdings, Inc. is a commercial-stage biopharmaceutical company focused on developing and commercializing innovative therapies for rare neurological and central nervous system disorders. Its primary market is the United States, with its core product serving patients living with narcolepsy and other sleep-related CNS conditions across adult and pediatric segments.
Prosperity Bancshares, Inc. is a bank holding company headquartered in Houston, Texas with operations in Texas and central Oklahoma. As of December 31, 2019, the company operated 285 branches: 65 in the Houston area, including The Woodlands, Texas; 30 in South Texas, including Corpus Christi, Texas and Victoria, Texas; 75 in the Dallas–Fort Worth metroplex; 22 in East Texas; 29 in Central Texas, including Austin, Texas and San Antonio; 34 in West Texas, including Lubbock, Texas, Midland–Odess...
HRMY vs PB — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $243.8M | $367.6M |
| Net Profit | $22.5M | $116.3M |
| Gross Margin | 71.9% | — |
| Operating Margin | 15.8% | — |
| Net Margin | 9.2% | 31.6% |
| Revenue YoY | 21.1% | — |
| Net Profit YoY | -54.6% | -10.7% |
| EPS (diluted) | $0.38 | $1.16 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q1 26 | — | $367.6M | ||
| Q4 25 | $243.8M | $275.0M | ||
| Q3 25 | $239.5M | $273.4M | ||
| Q2 25 | $200.5M | $267.7M | ||
| Q1 25 | $184.7M | $265.4M | ||
| Q4 24 | $201.3M | $267.8M | ||
| Q3 24 | $186.0M | $261.7M | ||
| Q2 24 | $172.8M | $258.8M |
| Q1 26 | — | $116.3M | ||
| Q4 25 | $22.5M | $139.9M | ||
| Q3 25 | $50.9M | $137.6M | ||
| Q2 25 | $39.8M | $135.2M | ||
| Q1 25 | $45.6M | $130.2M | ||
| Q4 24 | $49.5M | $130.1M | ||
| Q3 24 | $46.1M | $127.3M | ||
| Q2 24 | $11.6M | $111.6M |
| Q1 26 | — | — | ||
| Q4 25 | 71.9% | — | ||
| Q3 25 | 75.1% | — | ||
| Q2 25 | 81.0% | — | ||
| Q1 25 | 82.7% | — | ||
| Q4 24 | 73.0% | — | ||
| Q3 24 | 77.0% | — | ||
| Q2 24 | 81.4% | — |
| Q1 26 | — | — | ||
| Q4 25 | 15.8% | 65.1% | ||
| Q3 25 | 27.3% | 64.4% | ||
| Q2 25 | 24.0% | 64.3% | ||
| Q1 25 | 30.4% | 62.7% | ||
| Q4 24 | 27.7% | 62.0% | ||
| Q3 24 | 33.2% | 62.1% | ||
| Q2 24 | 12.4% | 55.2% |
| Q1 26 | — | 31.6% | ||
| Q4 25 | 9.2% | 50.9% | ||
| Q3 25 | 21.2% | 50.3% | ||
| Q2 25 | 19.8% | 50.5% | ||
| Q1 25 | 24.7% | 49.1% | ||
| Q4 24 | 24.6% | 48.6% | ||
| Q3 24 | 24.8% | 48.6% | ||
| Q2 24 | 6.7% | 43.1% |
| Q1 26 | — | $1.16 | ||
| Q4 25 | $0.38 | $1.48 | ||
| Q3 25 | $0.87 | $1.45 | ||
| Q2 25 | $0.68 | $1.42 | ||
| Q1 25 | $0.78 | $1.37 | ||
| Q4 24 | $0.85 | $1.36 | ||
| Q3 24 | $0.79 | $1.34 | ||
| Q2 24 | $0.20 | $1.17 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $775.3M | — |
| Total DebtLower is stronger | $163.7M | — |
| Stockholders' EquityBook value | $870.2M | $8.2B |
| Total Assets | $1.3B | $43.6B |
| Debt / EquityLower = less leverage | 0.19× | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $775.3M | — | ||
| Q3 25 | $672.6M | — | ||
| Q2 25 | $565.3M | — | ||
| Q1 25 | $507.0M | — | ||
| Q4 24 | $467.2M | — | ||
| Q3 24 | $410.5M | — | ||
| Q2 24 | $346.9M | — |
| Q1 26 | — | — | ||
| Q4 25 | $163.7M | — | ||
| Q3 25 | $168.5M | — | ||
| Q2 25 | $172.1M | — | ||
| Q1 25 | $175.7M | — | ||
| Q4 24 | $179.3M | — | ||
| Q3 24 | $182.8M | — | ||
| Q2 24 | $186.4M | — |
| Q1 26 | — | $8.2B | ||
| Q4 25 | $870.2M | $7.6B | ||
| Q3 25 | $835.1M | $7.7B | ||
| Q2 25 | $773.1M | $7.6B | ||
| Q1 25 | $720.5M | $7.5B | ||
| Q4 24 | $659.2M | $7.4B | ||
| Q3 24 | $596.8M | $7.4B | ||
| Q2 24 | $538.6M | $7.3B |
| Q1 26 | — | $43.6B | ||
| Q4 25 | $1.3B | $38.5B | ||
| Q3 25 | $1.2B | $38.3B | ||
| Q2 25 | $1.1B | $38.4B | ||
| Q1 25 | $1.1B | $38.8B | ||
| Q4 24 | $999.2M | $39.6B | ||
| Q3 24 | $928.1M | $40.1B | ||
| Q2 24 | $858.4M | $39.8B |
| Q1 26 | — | — | ||
| Q4 25 | 0.19× | — | ||
| Q3 25 | 0.20× | — | ||
| Q2 25 | 0.22× | — | ||
| Q1 25 | 0.24× | — | ||
| Q4 24 | 0.27× | — | ||
| Q3 24 | 0.31× | — | ||
| Q2 24 | 0.35× | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $126.2M | — |
| Free Cash FlowOCF − Capex | $126.0M | — |
| FCF MarginFCF / Revenue | 51.7% | — |
| Capex IntensityCapex / Revenue | 0.0% | — |
| Cash ConversionOCF / Net Profit | 5.61× | — |
| TTM Free Cash FlowTrailing 4 quarters | $347.9M | — |
8-quarter trend — quarters aligned by calendar period.
| Q1 26 | — | — | ||
| Q4 25 | $126.2M | $78.3M | ||
| Q3 25 | $108.7M | $194.8M | ||
| Q2 25 | $79.3M | $98.2M | ||
| Q1 25 | $34.0M | $178.2M | ||
| Q4 24 | $75.6M | $-205.8M | ||
| Q3 24 | $70.5M | $274.6M | ||
| Q2 24 | $42.6M | $216.5M |
| Q1 26 | — | — | ||
| Q4 25 | $126.0M | $68.5M | ||
| Q3 25 | $108.7M | $185.7M | ||
| Q2 25 | $79.3M | $91.8M | ||
| Q1 25 | $33.9M | $171.1M | ||
| Q4 24 | $75.0M | $-210.7M | ||
| Q3 24 | $70.5M | $270.2M | ||
| Q2 24 | $42.0M | $211.8M |
| Q1 26 | — | — | ||
| Q4 25 | 51.7% | 24.9% | ||
| Q3 25 | 45.4% | 67.9% | ||
| Q2 25 | 39.6% | 34.3% | ||
| Q1 25 | 18.3% | 64.5% | ||
| Q4 24 | 37.3% | -78.7% | ||
| Q3 24 | 37.9% | 103.3% | ||
| Q2 24 | 24.3% | 81.8% |
| Q1 26 | — | — | ||
| Q4 25 | 0.0% | 3.6% | ||
| Q3 25 | 0.0% | 3.3% | ||
| Q2 25 | 0.0% | 2.4% | ||
| Q1 25 | 0.1% | 2.7% | ||
| Q4 24 | 0.3% | 1.8% | ||
| Q3 24 | 0.0% | 1.7% | ||
| Q2 24 | 0.4% | 1.8% |
| Q1 26 | — | — | ||
| Q4 25 | 5.61× | 0.56× | ||
| Q3 25 | 2.14× | 1.42× | ||
| Q2 25 | 1.99× | 0.73× | ||
| Q1 25 | 0.75× | 1.37× | ||
| Q4 24 | 1.53× | -1.58× | ||
| Q3 24 | 1.53× | 2.16× | ||
| Q2 24 | 3.68× | 1.94× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
HRMY
Segment breakdown not available.
PB
| Net Interest Income | $321.1M | 87% |
| Noninterest Income | $46.5M | 13% |
