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Side-by-side financial comparison of HEALTHSTREAM INC (HSTM) and RHYTHM PHARMACEUTICALS, INC. (RYTM). Click either name above to swap in a different company.

HEALTHSTREAM INC is the larger business by last-quarter revenue ($79.7M vs $57.3M, roughly 1.4× RHYTHM PHARMACEUTICALS, INC.). On growth, RHYTHM PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (36.9% vs 7.4%). Over the past eight quarters, RHYTHM PHARMACEUTICALS, INC.'s revenue compounded faster (48.5% CAGR vs 4.7%).

HealthStream Inc is a leading U.S.-based provider of workforce development, compliance, and training solutions tailored for the healthcare industry. It offers cloud-based platforms covering clinical skill training, talent management, patient safety education, and regulatory adherence tools, serving over 4,000 healthcare organizations including hospitals, clinics, and long-term care facilities nationwide.

Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.

HSTM vs RYTM — Head-to-Head

Bigger by revenue
HSTM
HSTM
1.4× larger
HSTM
$79.7M
$57.3M
RYTM
Growing faster (revenue YoY)
RYTM
RYTM
+29.5% gap
RYTM
36.9%
7.4%
HSTM
Faster 2-yr revenue CAGR
RYTM
RYTM
Annualised
RYTM
48.5%
4.7%
HSTM

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
HSTM
HSTM
RYTM
RYTM
Revenue
$79.7M
$57.3M
Net Profit
$-47.5M
Gross Margin
91.6%
Operating Margin
3.0%
-82.2%
Net Margin
-83.0%
Revenue YoY
7.4%
36.9%
Net Profit YoY
-9.6%
EPS (diluted)
$0.09
$-0.73

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
HSTM
HSTM
RYTM
RYTM
Q4 25
$79.7M
$57.3M
Q3 25
$76.5M
$51.3M
Q2 25
$74.4M
$48.5M
Q1 25
$73.5M
$32.7M
Q4 24
$74.2M
$41.8M
Q3 24
$73.1M
$33.3M
Q2 24
$71.6M
$29.1M
Q1 24
$72.8M
$26.0M
Net Profit
HSTM
HSTM
RYTM
RYTM
Q4 25
$-47.5M
Q3 25
$6.1M
$-52.9M
Q2 25
$5.4M
$-46.6M
Q1 25
$4.3M
$-49.5M
Q4 24
$-43.3M
Q3 24
$5.7M
$-43.6M
Q2 24
$4.2M
$-32.3M
Q1 24
$5.2M
$-141.4M
Gross Margin
HSTM
HSTM
RYTM
RYTM
Q4 25
91.6%
Q3 25
89.3%
Q2 25
88.6%
Q1 25
88.8%
Q4 24
90.9%
Q3 24
88.5%
Q2 24
89.9%
Q1 24
89.2%
Operating Margin
HSTM
HSTM
RYTM
RYTM
Q4 25
3.0%
-82.2%
Q3 25
9.9%
-102.6%
Q2 25
7.9%
-93.4%
Q1 25
6.0%
-143.7%
Q4 24
6.3%
-98.6%
Q3 24
8.9%
-132.0%
Q2 24
6.2%
-139.2%
Q1 24
7.8%
-538.7%
Net Margin
HSTM
HSTM
RYTM
RYTM
Q4 25
-83.0%
Q3 25
8.0%
-103.1%
Q2 25
7.2%
-96.1%
Q1 25
5.9%
-151.4%
Q4 24
-103.6%
Q3 24
7.8%
-131.2%
Q2 24
5.8%
-110.9%
Q1 24
7.2%
-544.4%
EPS (diluted)
HSTM
HSTM
RYTM
RYTM
Q4 25
$0.09
$-0.73
Q3 25
$0.20
$-0.82
Q2 25
$0.18
$-0.75
Q1 25
$0.14
$-0.81
Q4 24
$0.16
$-0.71
Q3 24
$0.19
$-0.73
Q2 24
$0.14
$-0.55
Q1 24
$0.17
$-2.35

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
HSTM
HSTM
RYTM
RYTM
Cash + ST InvestmentsLiquidity on hand
$36.2M
$388.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$354.0M
$139.1M
Total Assets
$520.4M
$480.2M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
HSTM
HSTM
RYTM
RYTM
Q4 25
$36.2M
$388.9M
Q3 25
$53.5M
$416.1M
Q2 25
$52.1M
$291.0M
Q1 25
$77.3M
$314.5M
Q4 24
$59.5M
$320.6M
Q3 24
$57.5M
$298.4M
Q2 24
$46.1M
$319.1M
Q1 24
$52.4M
$201.2M
Stockholders' Equity
HSTM
HSTM
RYTM
RYTM
Q4 25
$354.0M
$139.1M
Q3 25
$349.2M
$148.8M
Q2 25
$350.6M
$-11.9M
Q1 25
$362.8M
$18.9M
Q4 24
$359.4M
$21.7M
Q3 24
$355.5M
$11.2M
Q2 24
$349.2M
$39.3M
Q1 24
$344.9M
$61.6M
Total Assets
HSTM
HSTM
RYTM
RYTM
Q4 25
$520.4M
$480.2M
Q3 25
$499.9M
$506.9M
Q2 25
$500.1M
$372.7M
Q1 25
$524.0M
$386.7M
Q4 24
$510.8M
$392.3M
Q3 24
$502.8M
$363.6M
Q2 24
$499.6M
$381.8M
Q1 24
$511.6M
$258.7M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
HSTM
HSTM
RYTM
RYTM
Operating Cash FlowLast quarter
$13.2M
$-25.4M
Free Cash FlowOCF − Capex
$13.0M
FCF MarginFCF / Revenue
16.3%
Capex IntensityCapex / Revenue
0.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$59.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
HSTM
HSTM
RYTM
RYTM
Q4 25
$13.2M
$-25.4M
Q3 25
$18.0M
$-26.6M
Q2 25
$5.0M
$-23.3M
Q1 25
$27.1M
$-40.4M
Q4 24
$11.2M
$-18.8M
Q3 24
$19.1M
$-25.2M
Q2 24
$6.5M
$-29.1M
Q1 24
$20.9M
$-40.7M
Free Cash Flow
HSTM
HSTM
RYTM
RYTM
Q4 25
$13.0M
Q3 25
$17.9M
Q2 25
$2.7M
Q1 25
$26.0M
Q4 24
$11.0M
Q3 24
$18.8M
Q2 24
$6.3M
Q1 24
$20.2M
FCF Margin
HSTM
HSTM
RYTM
RYTM
Q4 25
16.3%
Q3 25
23.4%
Q2 25
3.6%
Q1 25
35.4%
Q4 24
14.8%
Q3 24
25.8%
Q2 24
8.8%
Q1 24
27.8%
Capex Intensity
HSTM
HSTM
RYTM
RYTM
Q4 25
0.3%
Q3 25
0.1%
Q2 25
3.1%
Q1 25
1.4%
Q4 24
0.3%
Q3 24
0.4%
Q2 24
0.2%
Q1 24
1.0%
Cash Conversion
HSTM
HSTM
RYTM
RYTM
Q4 25
Q3 25
2.96×
Q2 25
0.93×
Q1 25
6.25×
Q4 24
Q3 24
3.34×
Q2 24
1.55×
Q1 24
4.01×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

HSTM
HSTM

Subscription Services$77.0M97%
Professional Services$2.7M3%

RYTM
RYTM

Segment breakdown not available.

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