vs
Side-by-side financial comparison of HEALTHSTREAM INC (HSTM) and Twist Bioscience Corp (TWST). Click either name above to swap in a different company.
Twist Bioscience Corp is the larger business by last-quarter revenue ($103.7M vs $79.7M, roughly 1.3× HEALTHSTREAM INC). On growth, Twist Bioscience Corp posted the faster year-over-year revenue change (16.9% vs 7.4%). HEALTHSTREAM INC produced more free cash flow last quarter ($13.0M vs $-34.8M).
HealthStream Inc is a leading U.S.-based provider of workforce development, compliance, and training solutions tailored for the healthcare industry. It offers cloud-based platforms covering clinical skill training, talent management, patient safety education, and regulatory adherence tools, serving over 4,000 healthcare organizations including hospitals, clinics, and long-term care facilities nationwide.
Twist Bioscience is a public biotechnology company based in South San Francisco that manufactures synthetic DNA and DNA products for customers in a wide range of industries. Twist was founded in 2013 by Emily Leproust, Bill Banyai, and Bill Peck.
HSTM vs TWST — Head-to-Head
Income Statement — Q4 FY2025 vs Q1 FY2026
| Metric | | |
|---|---|---|
| Revenue | $79.7M | $103.7M |
| Net Profit | — | $-30.5M |
| Gross Margin | — | 52.0% |
| Operating Margin | 3.0% | -31.7% |
| Net Margin | — | -29.4% |
| Revenue YoY | 7.4% | 16.9% |
| Net Profit YoY | — | 3.4% |
| EPS (diluted) | $0.09 | $-0.50 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $79.7M | $103.7M | ||
| Q3 25 | $76.5M | — | ||
| Q2 25 | $74.4M | — | ||
| Q1 25 | $73.5M | — | ||
| Q4 24 | $74.2M | — | ||
| Q3 24 | $73.1M | — | ||
| Q2 24 | $71.6M | — | ||
| Q1 24 | $72.8M | — |
| Q4 25 | — | $-30.5M | ||
| Q3 25 | $6.1M | — | ||
| Q2 25 | $5.4M | — | ||
| Q1 25 | $4.3M | — | ||
| Q4 24 | — | — | ||
| Q3 24 | $5.7M | — | ||
| Q2 24 | $4.2M | — | ||
| Q1 24 | $5.2M | — |
| Q4 25 | — | 52.0% | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | 3.0% | -31.7% | ||
| Q3 25 | 9.9% | — | ||
| Q2 25 | 7.9% | — | ||
| Q1 25 | 6.0% | — | ||
| Q4 24 | 6.3% | — | ||
| Q3 24 | 8.9% | — | ||
| Q2 24 | 6.2% | — | ||
| Q1 24 | 7.8% | — |
| Q4 25 | — | -29.4% | ||
| Q3 25 | 8.0% | — | ||
| Q2 25 | 7.2% | — | ||
| Q1 25 | 5.9% | — | ||
| Q4 24 | — | — | ||
| Q3 24 | 7.8% | — | ||
| Q2 24 | 5.8% | — | ||
| Q1 24 | 7.2% | — |
| Q4 25 | $0.09 | $-0.50 | ||
| Q3 25 | $0.20 | — | ||
| Q2 25 | $0.18 | — | ||
| Q1 25 | $0.14 | — | ||
| Q4 24 | $0.16 | — | ||
| Q3 24 | $0.19 | — | ||
| Q2 24 | $0.14 | — | ||
| Q1 24 | $0.17 | — |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $36.2M | $197.9M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $354.0M | $456.1M |
| Total Assets | $520.4M | $638.1M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $36.2M | $197.9M | ||
| Q3 25 | $53.5M | — | ||
| Q2 25 | $52.1M | — | ||
| Q1 25 | $77.3M | — | ||
| Q4 24 | $59.5M | — | ||
| Q3 24 | $57.5M | — | ||
| Q2 24 | $46.1M | — | ||
| Q1 24 | $52.4M | — |
| Q4 25 | $354.0M | $456.1M | ||
| Q3 25 | $349.2M | — | ||
| Q2 25 | $350.6M | — | ||
| Q1 25 | $362.8M | — | ||
| Q4 24 | $359.4M | — | ||
| Q3 24 | $355.5M | — | ||
| Q2 24 | $349.2M | — | ||
| Q1 24 | $344.9M | — |
| Q4 25 | $520.4M | $638.1M | ||
| Q3 25 | $499.9M | — | ||
| Q2 25 | $500.1M | — | ||
| Q1 25 | $524.0M | — | ||
| Q4 24 | $510.8M | — | ||
| Q3 24 | $502.8M | — | ||
| Q2 24 | $499.6M | — | ||
| Q1 24 | $511.6M | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $13.2M | $-24.8M |
| Free Cash FlowOCF − Capex | $13.0M | $-34.8M |
| FCF MarginFCF / Revenue | 16.3% | -33.5% |
| Capex IntensityCapex / Revenue | 0.3% | 9.6% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | $59.6M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $13.2M | $-24.8M | ||
| Q3 25 | $18.0M | — | ||
| Q2 25 | $5.0M | — | ||
| Q1 25 | $27.1M | — | ||
| Q4 24 | $11.2M | — | ||
| Q3 24 | $19.1M | — | ||
| Q2 24 | $6.5M | — | ||
| Q1 24 | $20.9M | — |
| Q4 25 | $13.0M | $-34.8M | ||
| Q3 25 | $17.9M | — | ||
| Q2 25 | $2.7M | — | ||
| Q1 25 | $26.0M | — | ||
| Q4 24 | $11.0M | — | ||
| Q3 24 | $18.8M | — | ||
| Q2 24 | $6.3M | — | ||
| Q1 24 | $20.2M | — |
| Q4 25 | 16.3% | -33.5% | ||
| Q3 25 | 23.4% | — | ||
| Q2 25 | 3.6% | — | ||
| Q1 25 | 35.4% | — | ||
| Q4 24 | 14.8% | — | ||
| Q3 24 | 25.8% | — | ||
| Q2 24 | 8.8% | — | ||
| Q1 24 | 27.8% | — |
| Q4 25 | 0.3% | 9.6% | ||
| Q3 25 | 0.1% | — | ||
| Q2 25 | 3.1% | — | ||
| Q1 25 | 1.4% | — | ||
| Q4 24 | 0.3% | — | ||
| Q3 24 | 0.4% | — | ||
| Q2 24 | 0.2% | — | ||
| Q1 24 | 1.0% | — |
| Q4 25 | — | — | ||
| Q3 25 | 2.96× | — | ||
| Q2 25 | 0.93× | — | ||
| Q1 25 | 6.25× | — | ||
| Q4 24 | — | — | ||
| Q3 24 | 3.34× | — | ||
| Q2 24 | 1.55× | — | ||
| Q1 24 | 4.01× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
HSTM
| Subscription Services | $77.0M | 97% |
| Professional Services | $2.7M | 3% |
TWST
| Industrial Chemicals | $37.2M | 36% |
| Diagnostics | $35.3M | 34% |
| Food Or Agriculture | $12.8M | 12% |
| Academic Research | $12.2M | 12% |
| Health Care | $6.1M | 6% |
