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Side-by-side financial comparison of HERITAGE COMMERCE CORP (HTBK) and Zymeworks Inc. (ZYME). Click either name above to swap in a different company.

HERITAGE COMMERCE CORP is the larger business by last-quarter revenue ($53.6M vs $27.6M, roughly 1.9× Zymeworks Inc.). HERITAGE COMMERCE CORP runs the higher net margin — 28.2% vs -71.0%, a 99.2% gap on every dollar of revenue. On growth, Zymeworks Inc. posted the faster year-over-year revenue change (72.6% vs 15.6%). HERITAGE COMMERCE CORP produced more free cash flow last quarter ($61.3M vs $-31.8M).

The United States Chamber of Commerce (USCC) is a business association advocacy group and is the largest lobbying group in the United States. The group was founded in April 23, 1912, out of local chambers of commerce at the urging of President William Howard Taft and his secretary of commerce and labor Charles Nagel. President Taft's belief was that the "government needed to deal with a group that could speak with authority for the interests of business."

Zymeworks Inc. is a publicly held biotechnology company based in Vancouver, British Columbia, that develops protein therapeutics for the treatment of cancer as well as for autoimmune and inflammatory diseases. The products are based upon the company's molecular modeling software for optimizing protein structure. In 2014, Zymeworks raised $44 million across various funding rounds according to PitchBook, placing it among the top 10 HealthTech businesses in the world to raise the most capital th...

HTBK vs ZYME — Head-to-Head

Bigger by revenue
HTBK
HTBK
1.9× larger
HTBK
$53.6M
$27.6M
ZYME
Growing faster (revenue YoY)
ZYME
ZYME
+57.0% gap
ZYME
72.6%
15.6%
HTBK
Higher net margin
HTBK
HTBK
99.2% more per $
HTBK
28.2%
-71.0%
ZYME
More free cash flow
HTBK
HTBK
$93.1M more FCF
HTBK
$61.3M
$-31.8M
ZYME

Income Statement — Q4 FY2025 vs Q3 FY2025

Metric
HTBK
HTBK
ZYME
ZYME
Revenue
$53.6M
$27.6M
Net Profit
$15.1M
$-19.6M
Gross Margin
Operating Margin
41.0%
-80.1%
Net Margin
28.2%
-71.0%
Revenue YoY
15.6%
72.6%
Net Profit YoY
42.3%
34.3%
EPS (diluted)
$0.25
$-0.26

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
HTBK
HTBK
ZYME
ZYME
Q4 25
$53.6M
Q3 25
$50.0M
$27.6M
Q2 25
$47.8M
$48.7M
Q1 25
$46.1M
$27.1M
Q4 24
$46.4M
$31.0M
Q3 24
$42.2M
$16.0M
Q2 24
$41.7M
$19.2M
Q1 24
$42.1M
$10.0M
Net Profit
HTBK
HTBK
ZYME
ZYME
Q4 25
$15.1M
Q3 25
$14.7M
$-19.6M
Q2 25
$6.4M
$2.3M
Q1 25
$11.6M
$-22.6M
Q4 24
$10.6M
$-23.5M
Q3 24
$10.5M
$-29.9M
Q2 24
$9.2M
$-37.7M
Q1 24
$10.2M
$-31.7M
Operating Margin
HTBK
HTBK
ZYME
ZYME
Q4 25
41.0%
Q3 25
41.1%
-80.1%
Q2 25
18.7%
-1.4%
Q1 25
35.4%
-94.5%
Q4 24
31.8%
-71.6%
Q3 24
34.3%
-213.8%
Q2 24
31.3%
-222.9%
Q1 24
34.2%
-376.9%
Net Margin
HTBK
HTBK
ZYME
ZYME
Q4 25
28.2%
Q3 25
29.4%
-71.0%
Q2 25
13.4%
4.8%
Q1 25
25.2%
-83.5%
Q4 24
22.9%
-75.8%
Q3 24
24.9%
-186.6%
Q2 24
22.1%
-195.8%
Q1 24
24.1%
-315.6%
EPS (diluted)
HTBK
HTBK
ZYME
ZYME
Q4 25
$0.25
Q3 25
$0.24
$-0.26
Q2 25
$0.10
$0.03
Q1 25
$0.19
$-0.30
Q4 24
$0.17
$-0.32
Q3 24
$0.17
$-0.39
Q2 24
$0.15
$-0.49
Q1 24
$0.17
$-0.42

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
HTBK
HTBK
ZYME
ZYME
Cash + ST InvestmentsLiquidity on hand
$64.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$708.6M
$320.1M
Total Assets
$5.8B
$397.3M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
HTBK
HTBK
ZYME
ZYME
Q4 25
Q3 25
$64.8M
Q2 25
$98.3M
Q1 25
$76.2M
Q4 24
$66.1M
Q3 24
$122.4M
Q2 24
$71.0M
Q1 24
$114.8M
Stockholders' Equity
HTBK
HTBK
ZYME
ZYME
Q4 25
$708.6M
Q3 25
$700.0M
$320.1M
Q2 25
$694.7M
$334.5M
Q1 25
$696.2M
$325.0M
Q4 24
$689.7M
$338.8M
Q3 24
$685.4M
$367.0M
Q2 24
$679.2M
$406.2M
Q1 24
$676.3M
$438.0M
Total Assets
HTBK
HTBK
ZYME
ZYME
Q4 25
$5.8B
Q3 25
$5.6B
$397.3M
Q2 25
$5.5B
$408.4M
Q1 25
$5.5B
$425.5M
Q4 24
$5.6B
$463.1M
Q3 24
$5.6B
$487.2M
Q2 24
$5.3B
$515.6M
Q1 24
$5.3B
$553.8M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
HTBK
HTBK
ZYME
ZYME
Operating Cash FlowLast quarter
$61.7M
$-31.4M
Free Cash FlowOCF − Capex
$61.3M
$-31.8M
FCF MarginFCF / Revenue
114.3%
-115.2%
Capex IntensityCapex / Revenue
0.7%
1.5%
Cash ConversionOCF / Net Profit
4.08×
TTM Free Cash FlowTrailing 4 quarters
$-65.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
HTBK
HTBK
ZYME
ZYME
Q4 25
$61.7M
Q3 25
$18.9M
$-31.4M
Q2 25
$8.0M
$12.1M
Q1 25
$14.8M
$-3.4M
Q4 24
$39.0M
$-41.5M
Q3 24
$5.3M
$-5.9M
Q2 24
$10.5M
$-25.0M
Q1 24
$7.3M
$-37.7M
Free Cash Flow
HTBK
HTBK
ZYME
ZYME
Q4 25
$61.3M
Q3 25
$18.8M
$-31.8M
Q2 25
$11.6M
Q1 25
$-3.4M
Q4 24
$37.3M
$-41.8M
Q3 24
$4.9M
$-6.8M
Q2 24
$9.9M
$-25.6M
Q1 24
$6.9M
$-37.9M
FCF Margin
HTBK
HTBK
ZYME
ZYME
Q4 25
114.3%
Q3 25
37.7%
-115.2%
Q2 25
23.7%
Q1 25
-12.6%
Q4 24
80.5%
-134.8%
Q3 24
11.6%
-42.4%
Q2 24
23.6%
-133.0%
Q1 24
16.4%
-377.5%
Capex Intensity
HTBK
HTBK
ZYME
ZYME
Q4 25
0.7%
Q3 25
0.1%
1.5%
Q2 25
1.1%
Q1 25
0.1%
Q4 24
3.5%
1.0%
Q3 24
1.0%
5.6%
Q2 24
1.6%
3.1%
Q1 24
1.0%
1.8%
Cash Conversion
HTBK
HTBK
ZYME
ZYME
Q4 25
4.08×
Q3 25
1.28×
Q2 25
1.25×
5.21×
Q1 25
1.28×
Q4 24
3.67×
Q3 24
0.50×
Q2 24
1.14×
Q1 24
0.72×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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