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Side-by-side financial comparison of IMPACT BIOMEDICAL INC. (IBO) and PROTHENA CORP PUBLIC LTD CO (PRTA). Click either name above to swap in a different company.

PROTHENA CORP PUBLIC LTD CO is the larger business by last-quarter revenue ($21.0K vs $18.0K, roughly 1.2× IMPACT BIOMEDICAL INC.).

The National Institute of Biomedical Imaging and Bioengineering (NIBIB), founded at the National Institutes of Health (NIH) in 2000, is located in Bethesda, Maryland. It is one of 27 institutes and centers that are part of NIH, an agency of the U.S. Department of Health and Human Services (HHS).

Prothena Corporation plc is a late-stage clinical biotechnology firm focused on developing and commercializing innovative antibody therapies for neurodegenerative disorders, rare diseases and immune-related conditions. Its core pipeline targets unmet medical needs including amyloidosis, Parkinson's and Alzheimer's, serving key markets across North America, Europe and the Asia-Pacific.

IBO vs PRTA — Head-to-Head

Bigger by revenue
PRTA
PRTA
1.2× larger
PRTA
$21.0K
$18.0K
IBO

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
IBO
IBO
PRTA
PRTA
Revenue
$18.0K
$21.0K
Net Profit
$-1.5M
Gross Margin
94.4%
Operating Margin
-5266.7%
Net Margin
-8166.7%
Revenue YoY
-99.0%
Net Profit YoY
-134.6%
62.7%
EPS (diluted)
$-0.12

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IBO
IBO
PRTA
PRTA
Q4 25
$21.0K
Q3 25
$18.0K
$2.4M
Q2 25
$7.0K
$4.4M
Q1 25
$2.8M
Q4 24
$2.1M
Q3 24
$970.0K
Q2 24
$132.0M
Q1 24
$50.0K
Net Profit
IBO
IBO
PRTA
PRTA
Q4 25
Q3 25
$-1.5M
$-36.5M
Q2 25
$-14.3M
$-125.8M
Q1 25
$-60.2M
Q4 24
Q3 24
$-59.0M
Q2 24
$66.9M
Q1 24
$-72.2M
Gross Margin
IBO
IBO
PRTA
PRTA
Q4 25
Q3 25
94.4%
Q2 25
-57.1%
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Operating Margin
IBO
IBO
PRTA
PRTA
Q4 25
Q3 25
-5266.7%
-1666.3%
Q2 25
-16471.4%
-1914.4%
Q1 25
-2319.0%
Q4 24
Q3 24
-6857.0%
Q2 24
44.2%
Q1 24
-163056.0%
Net Margin
IBO
IBO
PRTA
PRTA
Q4 25
Q3 25
-8166.7%
-1513.1%
Q2 25
-204942.9%
-2845.4%
Q1 25
-2128.5%
Q4 24
Q3 24
-6082.6%
Q2 24
50.7%
Q1 24
-144478.0%
EPS (diluted)
IBO
IBO
PRTA
PRTA
Q4 25
Q3 25
$-0.12
$-0.68
Q2 25
$-1.18
$-2.34
Q1 25
$-1.12
Q4 24
Q3 24
$-1.10
Q2 24
$1.22
Q1 24
$-1.34

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IBO
IBO
PRTA
PRTA
Cash + ST InvestmentsLiquidity on hand
$12.0K
$307.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$-11.8M
$280.5M
Total Assets
$18.2M
$326.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IBO
IBO
PRTA
PRTA
Q4 25
$307.5M
Q3 25
$12.0K
$330.8M
Q2 25
$624.0K
$371.4M
Q1 25
$417.9M
Q4 24
$471.4M
Q3 24
$519.3M
Q2 24
$564.1M
Q1 24
$546.5M
Stockholders' Equity
IBO
IBO
PRTA
PRTA
Q4 25
$280.5M
Q3 25
$-11.8M
$295.0M
Q2 25
$-10.3M
$324.3M
Q1 25
$437.7M
Q4 24
$486.9M
Q3 24
$534.4M
Q2 24
$581.9M
Q1 24
$502.4M
Total Assets
IBO
IBO
PRTA
PRTA
Q4 25
$326.8M
Q3 25
$18.2M
$352.6M
Q2 25
$19.1M
$399.1M
Q1 25
$495.3M
Q4 24
$547.1M
Q3 24
$595.3M
Q2 24
$645.6M
Q1 24
$623.2M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IBO
IBO
PRTA
PRTA
Operating Cash FlowLast quarter
$-613.0K
$-163.6M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IBO
IBO
PRTA
PRTA
Q4 25
$-163.6M
Q3 25
$-613.0K
$-40.6M
Q2 25
$-694.0K
$-46.3M
Q1 25
$-53.4M
Q4 24
$-150.1M
Q3 24
$-45.2M
Q2 24
$16.0M
Q1 24
$-73.1M
Cash Conversion
IBO
IBO
PRTA
PRTA
Q4 25
Q3 25
Q2 25
Q1 25
Q4 24
Q3 24
Q2 24
0.24×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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