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Side-by-side financial comparison of IMPACT BIOMEDICAL INC. (IBO) and Shuttle Pharmaceuticals Holdings, Inc. (SHPH). Click either name above to swap in a different company.

Shuttle Pharmaceuticals Holdings, Inc. is the larger business by last-quarter revenue ($22.0K vs $18.0K, roughly 1.2× IMPACT BIOMEDICAL INC.). IMPACT BIOMEDICAL INC. runs the higher net margin — -8166.7% vs -9249.6%, a 1082.9% gap on every dollar of revenue.

The National Institute of Biomedical Imaging and Bioengineering (NIBIB), founded at the National Institutes of Health (NIH) in 2000, is located in Bethesda, Maryland. It is one of 27 institutes and centers that are part of NIH, an agency of the U.S. Department of Health and Human Services (HHS).

Shuttle Pharmaceuticals Holdings, Inc. is a US-based clinical-stage biopharmaceutical company focused on developing novel radioprotective therapies and cancer supportive care products. It primarily operates in the oncology care segment, targeting unmet medical needs to reduce side effects of radiation therapy for cancer patients, and collaborates with clinical research partners to advance its late-stage product pipeline.

IBO vs SHPH — Head-to-Head

Bigger by revenue
SHPH
SHPH
1.2× larger
SHPH
$22.0K
$18.0K
IBO
Higher net margin
IBO
IBO
1082.9% more per $
IBO
-8166.7%
-9249.6%
SHPH

Income Statement — Q3 FY2025 vs Q2 FY2024

Metric
IBO
IBO
SHPH
SHPH
Revenue
$18.0K
$22.0K
Net Profit
$-1.5M
$-2.0M
Gross Margin
94.4%
Operating Margin
-5266.7%
-6751.5%
Net Margin
-8166.7%
-9249.6%
Revenue YoY
14.0%
Net Profit YoY
-134.6%
7.0%
EPS (diluted)
$-0.12
$-24.12

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IBO
IBO
SHPH
SHPH
Q3 25
$18.0K
Q2 25
$7.0K
Q2 24
$22.0K
Q1 24
$13.7K
Q4 23
$43.3K
Q3 23
$20.8K
Q2 23
$19.3K
Q1 23
$16.7K
Net Profit
IBO
IBO
SHPH
SHPH
Q3 25
$-1.5M
Q2 25
$-14.3M
Q2 24
$-2.0M
Q1 24
$-1.7M
Q4 23
$-1.6M
Q3 23
$-1.8M
Q2 23
$-2.2M
Q1 23
$-975.1K
Gross Margin
IBO
IBO
SHPH
SHPH
Q3 25
94.4%
Q2 25
-57.1%
Q2 24
Q1 24
Q4 23
Q3 23
Q2 23
Q1 23
Operating Margin
IBO
IBO
SHPH
SHPH
Q3 25
-5266.7%
Q2 25
-16471.4%
Q2 24
-6751.5%
Q1 24
-10144.7%
Q4 23
-2964.0%
Q3 23
-7701.2%
Q2 23
-7607.0%
Q1 23
-9256.8%
Net Margin
IBO
IBO
SHPH
SHPH
Q3 25
-8166.7%
Q2 25
-204942.9%
Q2 24
-9249.6%
Q1 24
-12680.6%
Q4 23
-3790.4%
Q3 23
-8633.5%
Q2 23
-11337.4%
Q1 23
-5843.1%
EPS (diluted)
IBO
IBO
SHPH
SHPH
Q3 25
$-0.12
Q2 25
$-1.18
Q2 24
$-24.12
Q1 24
$-0.83
Q4 23
$-0.82
Q3 23
$-0.91
Q2 23
$-1.23
Q1 23
$-0.57

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IBO
IBO
SHPH
SHPH
Cash + ST InvestmentsLiquidity on hand
$12.0K
$2.3M
Total DebtLower is stronger
Stockholders' EquityBook value
$-11.8M
$801.4K
Total Assets
$18.2M
$2.8M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IBO
IBO
SHPH
SHPH
Q3 25
$12.0K
Q2 25
$624.0K
Q2 24
$2.3M
Q1 24
$4.2M
Q4 23
$5.5M
Q3 23
$6.8M
Q2 23
$8.4M
Q1 23
$10.2M
Stockholders' Equity
IBO
IBO
SHPH
SHPH
Q3 25
$-11.8M
Q2 25
$-10.3M
Q2 24
$801.4K
Q1 24
$2.8M
Q4 23
$4.1M
Q3 23
$5.6M
Q2 23
$6.9M
Q1 23
$6.9M
Total Assets
IBO
IBO
SHPH
SHPH
Q3 25
$18.2M
Q2 25
$19.1M
Q2 24
$2.8M
Q1 24
$4.8M
Q4 23
$6.0M
Q3 23
$7.4M
Q2 23
$8.8M
Q1 23
$10.4M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IBO
IBO
SHPH
SHPH
Operating Cash FlowLast quarter
$-613.0K
$-1.4M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IBO
IBO
SHPH
SHPH
Q3 25
$-613.0K
Q2 25
$-694.0K
Q2 24
$-1.4M
Q1 24
$-1.2M
Q4 23
$-1.1M
Q3 23
$-1.5M
Q2 23
$-1.6M
Q1 23
$-1.3M

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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