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Side-by-side financial comparison of IDEAYA Biosciences, Inc. (IDYA) and PROSPERITY BANCSHARES INC (PB). Click either name above to swap in a different company.

PROSPERITY BANCSHARES INC is the larger business by last-quarter revenue ($367.6M vs $207.8M, roughly 1.8× IDEAYA Biosciences, Inc.). IDEAYA Biosciences, Inc. runs the higher net margin — 57.4% vs 31.6%, a 25.7% gap on every dollar of revenue.

IDEAYA Biosciences, Inc. is a clinical-stage biotechnology company focused on oncology, developing targeted therapies and synthetic lethality treatments for patients with genetically defined cancers. It advances a pipeline of candidates across multiple tumor types, partnering with industry stakeholders to accelerate global access to innovative cancer care solutions.

Prosperity Bancshares, Inc. is a bank holding company headquartered in Houston, Texas with operations in Texas and central Oklahoma. As of December 31, 2019, the company operated 285 branches: 65 in the Houston area, including The Woodlands, Texas; 30 in South Texas, including Corpus Christi, Texas and Victoria, Texas; 75 in the Dallas–Fort Worth metroplex; 22 in East Texas; 29 in Central Texas, including Austin, Texas and San Antonio; 34 in West Texas, including Lubbock, Texas, Midland–Odess...

IDYA vs PB — Head-to-Head

Bigger by revenue
PB
PB
1.8× larger
PB
$367.6M
$207.8M
IDYA
Higher net margin
IDYA
IDYA
25.7% more per $
IDYA
57.4%
31.6%
PB

Income Statement — Q3 FY2025 vs Q1 FY2026

Metric
IDYA
IDYA
PB
PB
Revenue
$207.8M
$367.6M
Net Profit
$119.2M
$116.3M
Gross Margin
Operating Margin
52.2%
Net Margin
57.4%
31.6%
Revenue YoY
Net Profit YoY
330.1%
-10.7%
EPS (diluted)
$1.33
$1.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IDYA
IDYA
PB
PB
Q1 26
$367.6M
Q4 25
$275.0M
Q3 25
$207.8M
$273.4M
Q2 25
$267.7M
Q1 25
$265.4M
Q4 24
$267.8M
Q3 24
$0
$261.7M
Q2 24
$0
$258.8M
Net Profit
IDYA
IDYA
PB
PB
Q1 26
$116.3M
Q4 25
$139.9M
Q3 25
$119.2M
$137.6M
Q2 25
$135.2M
Q1 25
$130.2M
Q4 24
$130.1M
Q3 24
$-51.8M
$127.3M
Q2 24
$-52.8M
$111.6M
Operating Margin
IDYA
IDYA
PB
PB
Q1 26
Q4 25
65.1%
Q3 25
52.2%
64.4%
Q2 25
64.3%
Q1 25
62.7%
Q4 24
62.0%
Q3 24
62.1%
Q2 24
55.2%
Net Margin
IDYA
IDYA
PB
PB
Q1 26
31.6%
Q4 25
50.9%
Q3 25
57.4%
50.3%
Q2 25
50.5%
Q1 25
49.1%
Q4 24
48.6%
Q3 24
48.6%
Q2 24
43.1%
EPS (diluted)
IDYA
IDYA
PB
PB
Q1 26
$1.16
Q4 25
$1.48
Q3 25
$1.33
$1.45
Q2 25
$1.42
Q1 25
$1.37
Q4 24
$1.36
Q3 24
$-0.60
$1.34
Q2 24
$-0.68
$1.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IDYA
IDYA
PB
PB
Cash + ST InvestmentsLiquidity on hand
$786.9M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.1B
$8.2B
Total Assets
$1.2B
$43.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IDYA
IDYA
PB
PB
Q1 26
Q4 25
Q3 25
$786.9M
Q2 25
Q1 25
Q4 24
Q3 24
$920.0M
Q2 24
$701.7M
Stockholders' Equity
IDYA
IDYA
PB
PB
Q1 26
$8.2B
Q4 25
$7.6B
Q3 25
$1.1B
$7.7B
Q2 25
$7.6B
Q1 25
$7.5B
Q4 24
$7.4B
Q3 24
$1.2B
$7.4B
Q2 24
$931.7M
$7.3B
Total Assets
IDYA
IDYA
PB
PB
Q1 26
$43.6B
Q4 25
$38.5B
Q3 25
$1.2B
$38.3B
Q2 25
$38.4B
Q1 25
$38.8B
Q4 24
$39.6B
Q3 24
$1.2B
$40.1B
Q2 24
$973.7M
$39.8B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IDYA
IDYA
PB
PB
Operating Cash FlowLast quarter
$142.2M
Free Cash FlowOCF − Capex
$142.2M
FCF MarginFCF / Revenue
68.4%
Capex IntensityCapex / Revenue
0.0%
Cash ConversionOCF / Net Profit
1.19×
TTM Free Cash FlowTrailing 4 quarters
$13.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IDYA
IDYA
PB
PB
Q1 26
Q4 25
$78.3M
Q3 25
$142.2M
$194.8M
Q2 25
$98.2M
Q1 25
$178.2M
Q4 24
$-205.8M
Q3 24
$-49.2M
$274.6M
Q2 24
$-32.9M
$216.5M
Free Cash Flow
IDYA
IDYA
PB
PB
Q1 26
Q4 25
$68.5M
Q3 25
$142.2M
$185.7M
Q2 25
$91.8M
Q1 25
$171.1M
Q4 24
$-210.7M
Q3 24
$-49.7M
$270.2M
Q2 24
$-33.9M
$211.8M
FCF Margin
IDYA
IDYA
PB
PB
Q1 26
Q4 25
24.9%
Q3 25
68.4%
67.9%
Q2 25
34.3%
Q1 25
64.5%
Q4 24
-78.7%
Q3 24
103.3%
Q2 24
81.8%
Capex Intensity
IDYA
IDYA
PB
PB
Q1 26
Q4 25
3.6%
Q3 25
0.0%
3.3%
Q2 25
2.4%
Q1 25
2.7%
Q4 24
1.8%
Q3 24
1.7%
Q2 24
1.8%
Cash Conversion
IDYA
IDYA
PB
PB
Q1 26
Q4 25
0.56×
Q3 25
1.19×
1.42×
Q2 25
0.73×
Q1 25
1.37×
Q4 24
-1.58×
Q3 24
2.16×
Q2 24
1.94×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IDYA
IDYA

Segment breakdown not available.

PB
PB

Net Interest Income$321.1M87%
Noninterest Income$46.5M13%

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