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Side-by-side financial comparison of ILLUMINA, INC. (ILMN) and Life Time Group Holdings, Inc. (LTH). Click either name above to swap in a different company.

ILLUMINA, INC. is the larger business by last-quarter revenue ($1.2B vs $745.1M, roughly 1.6× Life Time Group Holdings, Inc.). ILLUMINA, INC. runs the higher net margin — 28.8% vs 16.5%, a 12.3% gap on every dollar of revenue. On growth, Life Time Group Holdings, Inc. posted the faster year-over-year revenue change (12.3% vs 5.0%). ILLUMINA, INC. produced more free cash flow last quarter ($267.0M vs $-64.6M). Over the past eight quarters, Life Time Group Holdings, Inc.'s revenue compounded faster (11.7% CAGR vs -0.7%).

Illumina, Inc. is an American biotechnology company, headquartered in San Diego, California. Incorporated on April 1, 1998, Illumina develops, manufactures, and markets integrated systems for the analysis of genetic variation and biological function. The company provides a line of products and services that serves the sequencing, genotyping and gene expression, and proteomics markets, and serves more than 155 countries.

Life Time Group Holdings, Inc. operates a network of premium athletic, fitness and wellness destinations across the United States. It offers diverse services including state-of-the-art gym facilities, group exercise classes, personal training, spa treatments, nutrition coaching, youth programs and co-working spaces for consumers pursuing holistic healthy lifestyles.

ILMN vs LTH — Head-to-Head

Bigger by revenue
ILMN
ILMN
1.6× larger
ILMN
$1.2B
$745.1M
LTH
Growing faster (revenue YoY)
LTH
LTH
+7.4% gap
LTH
12.3%
5.0%
ILMN
Higher net margin
ILMN
ILMN
12.3% more per $
ILMN
28.8%
16.5%
LTH
More free cash flow
ILMN
ILMN
$331.6M more FCF
ILMN
$267.0M
$-64.6M
LTH
Faster 2-yr revenue CAGR
LTH
LTH
Annualised
LTH
11.7%
-0.7%
ILMN

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
ILMN
ILMN
LTH
LTH
Revenue
$1.2B
$745.1M
Net Profit
$334.0M
$123.0M
Gross Margin
65.5%
49.1%
Operating Margin
17.4%
17.4%
Net Margin
28.8%
16.5%
Revenue YoY
5.0%
12.3%
Net Profit YoY
185.5%
231.0%
EPS (diluted)
$2.16
$0.55

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ILMN
ILMN
LTH
LTH
Q4 25
$1.2B
$745.1M
Q3 25
$782.6M
Q2 25
$761.5M
Q1 25
$706.0M
Q4 24
$1.1B
$663.3M
Q3 24
$1.1B
$693.2M
Q2 24
$1.1B
$667.8M
Q1 24
$1.1B
$596.7M
Net Profit
ILMN
ILMN
LTH
LTH
Q4 25
$334.0M
$123.0M
Q3 25
$102.4M
Q2 25
$72.1M
Q1 25
$76.1M
Q4 24
$186.0M
$37.2M
Q3 24
$705.0M
$41.4M
Q2 24
$-2.0B
$52.8M
Q1 24
$-126.0M
$24.9M
Gross Margin
ILMN
ILMN
LTH
LTH
Q4 25
65.5%
49.1%
Q3 25
47.1%
Q2 25
47.0%
Q1 25
47.5%
Q4 24
65.9%
48.2%
Q3 24
69.0%
46.5%
Q2 24
64.8%
46.8%
Q1 24
62.0%
46.1%
Operating Margin
ILMN
ILMN
LTH
LTH
Q4 25
17.4%
17.4%
Q3 25
17.3%
Q2 25
14.2%
Q1 25
15.2%
Q4 24
15.8%
13.1%
Q3 24
68.6%
13.5%
Q2 24
-147.2%
15.7%
Q1 24
-10.3%
12.1%
Net Margin
ILMN
ILMN
LTH
LTH
Q4 25
28.8%
16.5%
Q3 25
13.1%
Q2 25
9.5%
Q1 25
10.8%
Q4 24
16.8%
5.6%
Q3 24
65.3%
6.0%
Q2 24
-178.8%
7.9%
Q1 24
-11.7%
4.2%
EPS (diluted)
ILMN
ILMN
LTH
LTH
Q4 25
$2.16
$0.55
Q3 25
$0.45
Q2 25
$0.32
Q1 25
$0.34
Q4 24
$1.16
$0.17
Q3 24
$4.42
$0.19
Q2 24
$-12.48
$0.26
Q1 24
$-0.79
$0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ILMN
ILMN
LTH
LTH
Cash + ST InvestmentsLiquidity on hand
$1.6B
$204.8M
Total DebtLower is stronger
$1.5B
Stockholders' EquityBook value
$2.7B
$3.1B
Total Assets
$6.6B
$8.0B
Debt / EquityLower = less leverage
0.48×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ILMN
ILMN
LTH
LTH
Q4 25
$1.6B
$204.8M
Q3 25
$218.9M
Q2 25
$175.5M
Q1 25
$59.0M
Q4 24
$93.0M
$10.9M
Q3 24
$70.0M
$120.9M
Q2 24
$74.0M
$34.5M
Q1 24
$18.6M
Total Debt
ILMN
ILMN
LTH
LTH
Q4 25
$1.5B
Q3 25
$1.5B
Q2 25
$1.5B
Q1 25
$1.5B
Q4 24
$1.5B
Q3 24
$1.7B
Q2 24
$1.8B
Q1 24
$2.0B
Stockholders' Equity
ILMN
ILMN
LTH
LTH
Q4 25
$2.7B
$3.1B
Q3 25
$3.0B
Q2 25
$2.9B
Q1 25
$2.7B
Q4 24
$2.4B
$2.6B
Q3 24
$2.1B
$2.6B
Q2 24
$1.4B
$2.4B
Q1 24
$5.7B
$2.3B
Total Assets
ILMN
ILMN
LTH
LTH
Q4 25
$6.6B
$8.0B
Q3 25
$7.8B
Q2 25
$7.6B
Q1 25
$7.3B
Q4 24
$6.3B
$7.2B
Q3 24
$6.0B
$7.2B
Q2 24
$6.1B
$7.1B
Q1 24
$10.0B
$7.1B
Debt / Equity
ILMN
ILMN
LTH
LTH
Q4 25
0.48×
Q3 25
0.51×
Q2 25
0.53×
Q1 25
0.56×
Q4 24
0.59×
Q3 24
0.64×
Q2 24
0.78×
Q1 24
0.87×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
ILMN
ILMN
LTH
LTH
Operating Cash FlowLast quarter
$321.0M
$239.9M
Free Cash FlowOCF − Capex
$267.0M
$-64.6M
FCF MarginFCF / Revenue
23.0%
-8.7%
Capex IntensityCapex / Revenue
40.9%
Cash ConversionOCF / Net Profit
0.96×
1.95×
TTM Free Cash FlowTrailing 4 quarters
$935.0M
$-21.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
ILMN
ILMN
LTH
LTH
Q4 25
$321.0M
$239.9M
Q3 25
$251.1M
Q2 25
$195.7M
Q1 25
$183.9M
Q4 24
$364.0M
$163.1M
Q3 24
$316.0M
$151.1M
Q2 24
$80.0M
$170.4M
Q1 24
$77.0M
$90.4M
Free Cash Flow
ILMN
ILMN
LTH
LTH
Q4 25
$267.0M
$-64.6M
Q3 25
$28.6M
Q2 25
$-26.3M
Q1 25
$41.4M
Q4 24
$335.0M
$26.8M
Q3 24
$284.0M
$64.0M
Q2 24
$49.0M
$26.1M
Q1 24
$41.0M
$-66.4M
FCF Margin
ILMN
ILMN
LTH
LTH
Q4 25
23.0%
-8.7%
Q3 25
3.7%
Q2 25
-3.5%
Q1 25
5.9%
Q4 24
30.3%
4.0%
Q3 24
26.3%
9.2%
Q2 24
4.4%
3.9%
Q1 24
3.8%
-11.1%
Capex Intensity
ILMN
ILMN
LTH
LTH
Q4 25
40.9%
Q3 25
28.4%
Q2 25
29.2%
Q1 25
20.2%
Q4 24
2.6%
20.6%
Q3 24
3.0%
12.6%
Q2 24
2.8%
21.6%
Q1 24
3.3%
26.3%
Cash Conversion
ILMN
ILMN
LTH
LTH
Q4 25
0.96×
1.95×
Q3 25
2.45×
Q2 25
2.71×
Q1 25
2.41×
Q4 24
1.96×
4.39×
Q3 24
0.45×
3.65×
Q2 24
3.23×
Q1 24
3.63×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ILMN
ILMN

Product revenue$990.0M85%
Service and other revenue$169.0M15%

LTH
LTH

Membership$535.1M72%
In Center$191.2M26%
Other$18.8M3%

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