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Side-by-side financial comparison of First Internet Bancorp (INBK) and RHYTHM PHARMACEUTICALS, INC. (RYTM). Click either name above to swap in a different company.

RHYTHM PHARMACEUTICALS, INC. is the larger business by last-quarter revenue ($57.3M vs $30.3M, roughly 1.9× First Internet Bancorp). First Internet Bancorp runs the higher net margin — 17.4% vs -83.0%, a 100.4% gap on every dollar of revenue. On growth, RHYTHM PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (36.9% vs 28.8%). Over the past eight quarters, RHYTHM PHARMACEUTICALS, INC.'s revenue compounded faster (48.5% CAGR vs 2.1%).

First Internet Bank of Indiana (First IB) is the sole subsidiary of First Internet Bancorp, an American bank holding company headquartered in Fishers, Indiana. It was established as one of the first state-chartered banks to operate exclusively online and via telephone, without any physical branches.

Rhythm Pharmaceuticals is a biopharmaceutical firm focused on developing and commercializing targeted therapies for rare genetic disorders causing severe unmanageable obesity, including POMC deficiency, LEPR deficiency, and Bardet-Biedl syndrome. It serves patients in North America and Europe who lack effective standard treatments for their chronic life-altering conditions.

INBK vs RYTM — Head-to-Head

Bigger by revenue
RYTM
RYTM
1.9× larger
RYTM
$57.3M
$30.3M
INBK
Growing faster (revenue YoY)
RYTM
RYTM
+8.1% gap
RYTM
36.9%
28.8%
INBK
Higher net margin
INBK
INBK
100.4% more per $
INBK
17.4%
-83.0%
RYTM
Faster 2-yr revenue CAGR
RYTM
RYTM
Annualised
RYTM
48.5%
2.1%
INBK

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
INBK
INBK
RYTM
RYTM
Revenue
$30.3M
$57.3M
Net Profit
$5.3M
$-47.5M
Gross Margin
91.6%
Operating Margin
18.1%
-82.2%
Net Margin
17.4%
-83.0%
Revenue YoY
28.8%
36.9%
Net Profit YoY
-27.8%
-9.6%
EPS (diluted)
$0.60
$-0.73

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
INBK
INBK
RYTM
RYTM
Q4 25
$30.3M
$57.3M
Q3 25
$5.7M
$51.3M
Q2 25
$33.5M
$48.5M
Q1 25
$35.5M
$32.7M
Q4 24
$39.5M
$41.8M
Q3 24
$33.8M
$33.3M
Q2 24
$32.4M
$29.1M
Q1 24
$29.1M
$26.0M
Net Profit
INBK
INBK
RYTM
RYTM
Q4 25
$5.3M
$-47.5M
Q3 25
$-41.6M
$-52.9M
Q2 25
$193.0K
$-46.6M
Q1 25
$943.0K
$-49.5M
Q4 24
$7.3M
$-43.3M
Q3 24
$7.0M
$-43.6M
Q2 24
$5.8M
$-32.3M
Q1 24
$5.2M
$-141.4M
Gross Margin
INBK
INBK
RYTM
RYTM
Q4 25
91.6%
Q3 25
89.3%
Q2 25
88.6%
Q1 25
88.8%
Q4 24
90.9%
Q3 24
88.5%
Q2 24
89.9%
Q1 24
89.2%
Operating Margin
INBK
INBK
RYTM
RYTM
Q4 25
18.1%
-82.2%
Q3 25
-956.1%
-102.6%
Q2 25
-5.5%
-93.4%
Q1 25
0.1%
-143.7%
Q4 24
21.1%
-98.6%
Q3 24
22.5%
-132.0%
Q2 24
18.5%
-139.2%
Q1 24
19.3%
-538.7%
Net Margin
INBK
INBK
RYTM
RYTM
Q4 25
17.4%
-83.0%
Q3 25
-729.1%
-103.1%
Q2 25
0.6%
-96.1%
Q1 25
2.7%
-151.4%
Q4 24
18.6%
-103.6%
Q3 24
20.7%
-131.2%
Q2 24
17.8%
-110.9%
Q1 24
17.8%
-544.4%
EPS (diluted)
INBK
INBK
RYTM
RYTM
Q4 25
$0.60
$-0.73
Q3 25
$-4.76
$-0.82
Q2 25
$0.02
$-0.75
Q1 25
$0.11
$-0.81
Q4 24
$0.82
$-0.71
Q3 24
$0.80
$-0.73
Q2 24
$0.67
$-0.55
Q1 24
$0.59
$-2.35

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
INBK
INBK
RYTM
RYTM
Cash + ST InvestmentsLiquidity on hand
$456.8M
$388.9M
Total DebtLower is stronger
$249.5M
Stockholders' EquityBook value
$359.8M
$139.1M
Total Assets
$5.6B
$480.2M
Debt / EquityLower = less leverage
0.69×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
INBK
INBK
RYTM
RYTM
Q4 25
$456.8M
$388.9M
Q3 25
$787.7M
$416.1M
Q2 25
$446.4M
$291.0M
Q1 25
$394.5M
$314.5M
Q4 24
$466.4M
$320.6M
Q3 24
$712.5M
$298.4M
Q2 24
$396.8M
$319.1M
Q1 24
$481.3M
$201.2M
Total Debt
INBK
INBK
RYTM
RYTM
Q4 25
$249.5M
Q3 25
Q2 25
Q1 25
Q4 24
$295.0M
Q3 24
Q2 24
Q1 24
Stockholders' Equity
INBK
INBK
RYTM
RYTM
Q4 25
$359.8M
$139.1M
Q3 25
$352.2M
$148.8M
Q2 25
$390.2M
$-11.9M
Q1 25
$387.7M
$18.9M
Q4 24
$384.1M
$21.7M
Q3 24
$385.1M
$11.2M
Q2 24
$372.0M
$39.3M
Q1 24
$366.7M
$61.6M
Total Assets
INBK
INBK
RYTM
RYTM
Q4 25
$5.6B
$480.2M
Q3 25
$5.6B
$506.9M
Q2 25
$6.1B
$372.7M
Q1 25
$5.9B
$386.7M
Q4 24
$5.7B
$392.3M
Q3 24
$5.8B
$363.6M
Q2 24
$5.3B
$381.8M
Q1 24
$5.3B
$258.7M
Debt / Equity
INBK
INBK
RYTM
RYTM
Q4 25
0.69×
Q3 25
Q2 25
Q1 25
Q4 24
0.77×
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
INBK
INBK
RYTM
RYTM
Operating Cash FlowLast quarter
$3.4M
$-25.4M
Free Cash FlowOCF − Capex
$2.2M
FCF MarginFCF / Revenue
7.3%
Capex IntensityCapex / Revenue
4.0%
Cash ConversionOCF / Net Profit
0.65×
TTM Free Cash FlowTrailing 4 quarters
$-19.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
INBK
INBK
RYTM
RYTM
Q4 25
$3.4M
$-25.4M
Q3 25
$37.1M
$-26.6M
Q2 25
$-90.2M
$-23.3M
Q1 25
$32.8M
$-40.4M
Q4 24
$13.0M
$-18.8M
Q3 24
$331.0K
$-25.2M
Q2 24
$16.0M
$-29.1M
Q1 24
$2.8M
$-40.7M
Free Cash Flow
INBK
INBK
RYTM
RYTM
Q4 25
$2.2M
Q3 25
$37.0M
Q2 25
$-90.8M
Q1 25
$32.6M
Q4 24
$10.4M
Q3 24
$-270.0K
Q2 24
$15.5M
Q1 24
$1.9M
FCF Margin
INBK
INBK
RYTM
RYTM
Q4 25
7.3%
Q3 25
648.0%
Q2 25
-270.7%
Q1 25
91.9%
Q4 24
26.3%
Q3 24
-0.8%
Q2 24
47.8%
Q1 24
6.4%
Capex Intensity
INBK
INBK
RYTM
RYTM
Q4 25
4.0%
Q3 25
1.9%
Q2 25
1.9%
Q1 25
0.5%
Q4 24
6.6%
Q3 24
1.8%
Q2 24
1.7%
Q1 24
3.2%
Cash Conversion
INBK
INBK
RYTM
RYTM
Q4 25
0.65×
Q3 25
Q2 25
-467.21×
Q1 25
34.81×
Q4 24
1.77×
Q3 24
0.05×
Q2 24
2.77×
Q1 24
0.54×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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