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Side-by-side financial comparison of IOVANCE BIOTHERAPEUTICS, INC. (IOVA) and REGIS CORP (RGS). Click either name above to swap in a different company.

IOVANCE BIOTHERAPEUTICS, INC. is the larger business by last-quarter revenue ($86.8M vs $57.1M, roughly 1.5× REGIS CORP). On growth, REGIS CORP posted the faster year-over-year revenue change (22.3% vs 17.7%). REGIS CORP produced more free cash flow last quarter ($891.0K vs $-61.9M). Over the past eight quarters, IOVANCE BIOTHERAPEUTICS, INC.'s revenue compounded faster (1001.6% CAGR vs 7.8%).

Iovance Biotherapeutics, Inc. is a biopharmaceutical startup based in San Carlos, California. The company works to develop tumor-infiltrating lymphocyte (TIL) therapies against cancer.

Regis Corporation is an American operator of hair salons. As of August 2021, it has 5,563 franchised and 276 company-owned salons. Its headquarters are in Minneapolis, Minnesota.

IOVA vs RGS — Head-to-Head

Bigger by revenue
IOVA
IOVA
1.5× larger
IOVA
$86.8M
$57.1M
RGS
Growing faster (revenue YoY)
RGS
RGS
+4.5% gap
RGS
22.3%
17.7%
IOVA
More free cash flow
RGS
RGS
$62.8M more FCF
RGS
$891.0K
$-61.9M
IOVA
Faster 2-yr revenue CAGR
IOVA
IOVA
Annualised
IOVA
1001.6%
7.8%
RGS

Income Statement — Q4 FY2025 vs Q2 FY2026

Metric
IOVA
IOVA
RGS
RGS
Revenue
$86.8M
$57.1M
Net Profit
$456.0K
Gross Margin
67.4%
Operating Margin
-84.7%
10.8%
Net Margin
0.8%
Revenue YoY
17.7%
22.3%
Net Profit YoY
-94.0%
EPS (diluted)
$0.16

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IOVA
IOVA
RGS
RGS
Q4 25
$86.8M
$57.1M
Q3 25
$67.5M
$59.0M
Q2 25
$60.0M
$60.4M
Q1 25
$49.3M
$57.0M
Q4 24
$73.7M
$46.7M
Q3 24
$58.6M
$46.1M
Q2 24
$31.1M
$49.4M
Q1 24
$715.0K
$49.2M
Net Profit
IOVA
IOVA
RGS
RGS
Q4 25
$456.0K
Q3 25
$-91.3M
$1.4M
Q2 25
$-111.7M
$116.5M
Q1 25
$-116.2M
$250.0K
Q4 24
$7.6M
Q3 24
$-83.5M
$-853.0K
Q2 24
$-97.1M
$91.2M
Q1 24
$-113.0M
$-2.3M
Gross Margin
IOVA
IOVA
RGS
RGS
Q4 25
67.4%
Q3 25
43.0%
Q2 25
5.5%
Q1 25
-0.8%
Q4 24
68.7%
Q3 24
46.2%
Q2 24
-0.8%
Q1 24
Operating Margin
IOVA
IOVA
RGS
RGS
Q4 25
-84.7%
10.8%
Q3 25
-140.7%
10.0%
Q2 25
-189.8%
12.1%
Q1 25
-245.8%
8.8%
Q4 24
-117.5%
11.8%
Q3 24
-152.1%
4.6%
Q2 24
-327.6%
Q1 24
-16464.6%
8.3%
Net Margin
IOVA
IOVA
RGS
RGS
Q4 25
0.8%
Q3 25
-135.3%
2.3%
Q2 25
-186.2%
192.9%
Q1 25
-235.5%
0.4%
Q4 24
16.4%
Q3 24
-142.7%
-1.9%
Q2 24
-312.2%
184.7%
Q1 24
-15800.8%
-4.7%
EPS (diluted)
IOVA
IOVA
RGS
RGS
Q4 25
$0.16
Q3 25
$0.49
Q2 25
$-0.33
$43.67
Q1 25
$-0.36
$0.08
Q4 24
$-0.24
$2.71
Q3 24
$-0.28
$-0.36
Q2 24
$-0.34
$38.40
Q1 24
$-0.42
$-1.00

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IOVA
IOVA
RGS
RGS
Cash + ST InvestmentsLiquidity on hand
$297.0M
$18.4M
Total DebtLower is stronger
$113.3M
Stockholders' EquityBook value
$698.6M
$188.7M
Total Assets
$913.2M
$588.3M
Debt / EquityLower = less leverage
0.60×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IOVA
IOVA
RGS
RGS
Q4 25
$297.0M
$18.4M
Q3 25
$300.8M
$16.6M
Q2 25
$301.2M
$17.0M
Q1 25
$359.7M
$13.3M
Q4 24
$323.8M
$10.2M
Q3 24
$397.5M
$6.3M
Q2 24
$412.5M
$10.1M
Q1 24
$356.2M
$5.9M
Total Debt
IOVA
IOVA
RGS
RGS
Q4 25
$113.3M
Q3 25
$111.3M
Q2 25
$110.8M
Q1 25
$112.0M
Q4 24
$111.5M
Q3 24
$95.2M
Q2 24
$99.5M
Q1 24
$179.7M
Stockholders' Equity
IOVA
IOVA
RGS
RGS
Q4 25
$698.6M
$188.7M
Q3 25
$702.3M
$187.6M
Q2 25
$698.5M
$185.6M
Q1 25
$767.9M
$68.6M
Q4 24
$710.4M
$66.7M
Q3 24
$773.5M
$56.4M
Q2 24
$768.5M
$56.8M
Q1 24
$680.0M
$-35.8M
Total Assets
IOVA
IOVA
RGS
RGS
Q4 25
$913.2M
$588.3M
Q3 25
$904.9M
$592.1M
Q2 25
$907.4M
$599.0M
Q1 25
$966.7M
$511.2M
Q4 24
$910.4M
$530.1M
Q3 24
$991.1M
$508.9M
Q2 24
$964.3M
$530.5M
Q1 24
$869.8M
$543.7M
Debt / Equity
IOVA
IOVA
RGS
RGS
Q4 25
0.60×
Q3 25
0.59×
Q2 25
0.60×
Q1 25
1.63×
Q4 24
1.67×
Q3 24
1.69×
Q2 24
1.75×
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IOVA
IOVA
RGS
RGS
Operating Cash FlowLast quarter
$-52.6M
$1.7M
Free Cash FlowOCF − Capex
$-61.9M
$891.0K
FCF MarginFCF / Revenue
-71.3%
1.6%
Capex IntensityCapex / Revenue
10.7%
1.4%
Cash ConversionOCF / Net Profit
3.65×
TTM Free Cash FlowTrailing 4 quarters
$-336.2M
$14.9M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IOVA
IOVA
RGS
RGS
Q4 25
$-52.6M
$1.7M
Q3 25
$-78.7M
$2.3M
Q2 25
$-67.4M
$6.8M
Q1 25
$-103.7M
$6.2M
Q4 24
$-73.3M
$2.1M
Q3 24
$-59.0M
$-1.3M
Q2 24
$-98.4M
$5.1M
Q1 24
$-122.3M
$-277.0K
Free Cash Flow
IOVA
IOVA
RGS
RGS
Q4 25
$-61.9M
$891.0K
Q3 25
$-89.5M
$1.9M
Q2 25
$-74.9M
$6.2M
Q1 25
$-109.9M
$5.9M
Q4 24
$-77.5M
$1.7M
Q3 24
$-61.3M
$-1.4M
Q2 24
$-98.9M
$5.1M
Q1 24
$-126.5M
$-326.0K
FCF Margin
IOVA
IOVA
RGS
RGS
Q4 25
-71.3%
1.6%
Q3 25
-132.7%
3.2%
Q2 25
-124.9%
10.3%
Q1 25
-222.8%
10.3%
Q4 24
-105.1%
3.6%
Q3 24
-104.6%
-3.0%
Q2 24
-317.9%
10.3%
Q1 24
-17685.3%
-0.7%
Capex Intensity
IOVA
IOVA
RGS
RGS
Q4 25
10.7%
1.4%
Q3 25
16.1%
0.7%
Q2 25
12.4%
0.9%
Q1 25
12.6%
0.6%
Q4 24
5.7%
0.9%
Q3 24
3.9%
0.0%
Q2 24
1.4%
0.0%
Q1 24
583.4%
0.1%
Cash Conversion
IOVA
IOVA
RGS
RGS
Q4 25
3.65×
Q3 25
1.68×
Q2 25
0.06×
Q1 25
24.80×
Q4 24
0.28×
Q3 24
Q2 24
0.06×
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

IOVA
IOVA

Amtagvi$64.9M75%
Proleukin$21.9M25%

RGS
RGS

Franchise Segment$37.9M66%
Royalty$13.6M24%
Other$2.8M5%
Fees$1.8M3%
Franchise Fees$1.0M2%

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