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Side-by-side financial comparison of IPG PHOTONICS CORP (IPGP) and Protagonist Therapeutics, Inc (PTGX). Click either name above to swap in a different company.
IPG PHOTONICS CORP is the larger business by last-quarter revenue ($274.5M vs $170.6M, roughly 1.6× Protagonist Therapeutics, Inc). Protagonist Therapeutics, Inc runs the higher net margin — 77.2% vs 4.8%, a 72.3% gap on every dollar of revenue. On growth, Protagonist Therapeutics, Inc posted the faster year-over-year revenue change (184.4% vs 17.1%). Protagonist Therapeutics, Inc produced more free cash flow last quarter ($182.8M vs $10.9M).
IPG Photonics Corporation is a manufacturer of fiber lasers. IPG Photonics developed and commercialized optical fiber lasers, which are used in a variety of applications including materials processing, medical applications and telecommunications. IPG has manufacturing facilities in the United States, Germany, Russia and Italy.
Protagonist Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering and developing novel peptide-based targeted therapies for unmet medical needs, primarily covering gastrointestinal disorders, inflammatory diseases and rare disease indications. Its lead product candidates target inflammatory bowel disease and other chronic immune-related conditions, with operations spanning global R&D and partnership collaborations.
IPGP vs PTGX — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2024
| Metric | | |
|---|---|---|
| Revenue | $274.5M | $170.6M |
| Net Profit | $13.3M | $131.7M |
| Gross Margin | 36.1% | — |
| Operating Margin | 1.2% | 74.3% |
| Net Margin | 4.8% | 77.2% |
| Revenue YoY | 17.1% | 184.4% |
| Net Profit YoY | 69.8% | 381.7% |
| EPS (diluted) | $0.30 | $2.01 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $274.5M | — | ||
| Q3 25 | $250.8M | — | ||
| Q2 25 | $250.7M | — | ||
| Q1 25 | $227.8M | — | ||
| Q4 24 | $234.3M | $170.6M | ||
| Q3 24 | $233.1M | — | ||
| Q2 24 | $257.6M | — | ||
| Q1 24 | $252.0M | $255.0M |
| Q4 25 | $13.3M | — | ||
| Q3 25 | $7.5M | — | ||
| Q2 25 | $6.6M | — | ||
| Q1 25 | $3.8M | — | ||
| Q4 24 | $7.8M | $131.7M | ||
| Q3 24 | $-233.6M | — | ||
| Q2 24 | $20.2M | — | ||
| Q1 24 | $24.1M | $207.3M |
| Q4 25 | 36.1% | — | ||
| Q3 25 | 39.5% | — | ||
| Q2 25 | 37.3% | — | ||
| Q1 25 | 39.4% | — | ||
| Q4 24 | 38.6% | — | ||
| Q3 24 | 23.2% | — | ||
| Q2 24 | 37.3% | — | ||
| Q1 24 | 38.7% | — |
| Q4 25 | 1.2% | — | ||
| Q3 25 | 3.1% | — | ||
| Q2 25 | 0.0% | — | ||
| Q1 25 | 0.8% | — | ||
| Q4 24 | 6.0% | 74.3% | ||
| Q3 24 | -108.7% | — | ||
| Q2 24 | 4.7% | — | ||
| Q1 24 | 7.6% | 80.9% |
| Q4 25 | 4.8% | — | ||
| Q3 25 | 3.0% | — | ||
| Q2 25 | 2.6% | — | ||
| Q1 25 | 1.6% | — | ||
| Q4 24 | 3.3% | 77.2% | ||
| Q3 24 | -100.2% | — | ||
| Q2 24 | 7.8% | — | ||
| Q1 24 | 9.6% | 81.3% |
| Q4 25 | $0.30 | — | ||
| Q3 25 | $0.18 | — | ||
| Q2 25 | $0.16 | — | ||
| Q1 25 | $0.09 | — | ||
| Q4 24 | $0.27 | $2.01 | ||
| Q3 24 | $-5.33 | — | ||
| Q2 24 | $0.45 | — | ||
| Q1 24 | $0.52 | $3.26 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $839.3M | $418.9M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $2.1B | $675.3M |
| Total Assets | $2.4B | $744.7M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $839.3M | — | ||
| Q3 25 | $870.4M | — | ||
| Q2 25 | $899.6M | — | ||
| Q1 25 | $926.9M | — | ||
| Q4 24 | $930.2M | $418.9M | ||
| Q3 24 | $1.0B | — | ||
| Q2 24 | $1.1B | — | ||
| Q1 24 | $1.1B | $322.6M |
| Q4 25 | $2.1B | — | ||
| Q3 25 | $2.1B | — | ||
| Q2 25 | $2.1B | — | ||
| Q1 25 | $2.1B | — | ||
| Q4 24 | $2.0B | $675.3M | ||
| Q3 24 | $2.1B | — | ||
| Q2 24 | $2.3B | — | ||
| Q1 24 | $2.3B | $560.4M |
| Q4 25 | $2.4B | — | ||
| Q3 25 | $2.4B | — | ||
| Q2 25 | $2.4B | — | ||
| Q1 25 | $2.3B | — | ||
| Q4 24 | $2.3B | $744.7M | ||
| Q3 24 | $2.4B | — | ||
| Q2 24 | $2.5B | — | ||
| Q1 24 | $2.6B | $629.3M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $28.8M | $184.2M |
| Free Cash FlowOCF − Capex | $10.9M | $182.8M |
| FCF MarginFCF / Revenue | 4.0% | 107.1% |
| Capex IntensityCapex / Revenue | 6.5% | 0.8% |
| Cash ConversionOCF / Net Profit | 2.17× | 1.40× |
| TTM Free Cash FlowTrailing 4 quarters | $-3.5M | $101.7M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $28.8M | — | ||
| Q3 25 | $35.3M | — | ||
| Q2 25 | $-2.2M | — | ||
| Q1 25 | $13.4M | — | ||
| Q4 24 | $73.8M | $184.2M | ||
| Q3 24 | $66.1M | — | ||
| Q2 24 | $53.5M | — | ||
| Q1 24 | $54.6M | $-27.4M |
| Q4 25 | $10.9M | — | ||
| Q3 25 | $14.6M | — | ||
| Q2 25 | $-17.6M | — | ||
| Q1 25 | $-11.4M | — | ||
| Q4 24 | $50.6M | $182.8M | ||
| Q3 24 | $43.0M | — | ||
| Q2 24 | $29.2M | — | ||
| Q1 24 | $26.5M | $-27.7M |
| Q4 25 | 4.0% | — | ||
| Q3 25 | 5.8% | — | ||
| Q2 25 | -7.0% | — | ||
| Q1 25 | -5.0% | — | ||
| Q4 24 | 21.6% | 107.1% | ||
| Q3 24 | 18.4% | — | ||
| Q2 24 | 11.3% | — | ||
| Q1 24 | 10.5% | -10.9% |
| Q4 25 | 6.5% | — | ||
| Q3 25 | 8.3% | — | ||
| Q2 25 | 6.1% | — | ||
| Q1 25 | 10.9% | — | ||
| Q4 24 | 9.9% | 0.8% | ||
| Q3 24 | 9.9% | — | ||
| Q2 24 | 9.4% | — | ||
| Q1 24 | 11.1% | 0.1% |
| Q4 25 | 2.17× | — | ||
| Q3 25 | 4.73× | — | ||
| Q2 25 | -0.34× | — | ||
| Q1 25 | 3.58× | — | ||
| Q4 24 | 9.44× | 1.40× | ||
| Q3 24 | — | — | ||
| Q2 24 | 2.65× | — | ||
| Q1 24 | 2.27× | -0.13× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
IPGP
| Materials Processing | $232.8M | 85% |
| Laser And Non Laser Systems | $38.8M | 14% |
| Transferred Over Time | $5.3M | 2% |
PTGX
Segment breakdown not available.
