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Side-by-side financial comparison of Opus Genetics, Inc. (IRD) and SIGA TECHNOLOGIES INC (SIGA). Click either name above to swap in a different company.

Opus Genetics, Inc. is the larger business by last-quarter revenue ($3.9M vs $3.8M, roughly 1.0× SIGA TECHNOLOGIES INC). On growth, Opus Genetics, Inc. posted the faster year-over-year revenue change (-10.2% vs -95.3%). Over the past eight quarters, Opus Genetics, Inc.'s revenue compounded faster (50.3% CAGR vs -61.4%).

Opus Genetics, Inc. is a clinical-stage biotechnology company specializing in the development of targeted gene therapies for inherited retinal diseases. It focuses on addressing unmet medical needs for patients living with rare, vision-threatening ocular conditions, with operations centered on advancing accessible therapeutic candidates for global rare disease patient populations.

SIGA Technologies, Inc. is an American pharmaceutical company founded in 1995, based in New York City, which develops and sells pharmaceutical solutions for the antiviral treatment of smallpox, monkeypox, cowpox, and vaccinia complications.

IRD vs SIGA — Head-to-Head

Bigger by revenue
IRD
IRD
1.0× larger
IRD
$3.9M
$3.8M
SIGA
Growing faster (revenue YoY)
IRD
IRD
+85.2% gap
IRD
-10.2%
-95.3%
SIGA
Faster 2-yr revenue CAGR
IRD
IRD
Annualised
IRD
50.3%
-61.4%
SIGA

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IRD
IRD
SIGA
SIGA
Revenue
$3.9M
$3.8M
Net Profit
Gross Margin
21.2%
Operating Margin
Net Margin
Revenue YoY
-10.2%
-95.3%
Net Profit YoY
53.0%
-111.9%
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRD
IRD
SIGA
SIGA
Q4 25
$3.9M
$3.8M
Q3 25
$3.1M
$2.6M
Q2 25
$2.9M
$81.1M
Q1 25
$4.4M
$7.0M
Q4 24
$4.3M
$81.5M
Q3 24
$3.9M
$10.0M
Q2 24
$1.1M
$21.8M
Q1 24
$1.7M
$25.4M
Net Profit
IRD
IRD
SIGA
SIGA
Q4 25
Q3 25
$-17.5M
$-6.4M
Q2 25
$-7.4M
$35.5M
Q1 25
$-8.2M
$-408.2K
Q4 24
$45.8M
Q3 24
$-7.5M
$1.3M
Q2 24
$-7.8M
$1.8M
Q1 24
$-7.1M
$10.3M
Gross Margin
IRD
IRD
SIGA
SIGA
Q4 25
21.2%
Q3 25
61.8%
Q2 25
68.5%
Q1 25
97.8%
Q4 24
82.7%
Q3 24
83.8%
Q2 24
43.6%
Q1 24
87.3%
Operating Margin
IRD
IRD
SIGA
SIGA
Q4 25
Q3 25
-269.9%
-390.2%
Q2 25
-309.0%
56.3%
Q1 25
-227.2%
-32.0%
Q4 24
70.1%
Q3 24
-207.1%
5.4%
Q2 24
-748.9%
5.0%
Q1 24
-450.5%
44.3%
Net Margin
IRD
IRD
SIGA
SIGA
Q4 25
Q3 25
-566.9%
-243.0%
Q2 25
-257.5%
43.7%
Q1 25
-187.5%
-5.8%
Q4 24
56.2%
Q3 24
-194.6%
13.4%
Q2 24
-698.3%
8.4%
Q1 24
-415.3%
40.4%
EPS (diluted)
IRD
IRD
SIGA
SIGA
Q4 25
Q3 25
$-0.25
$-0.09
Q2 25
$-0.12
$0.49
Q1 25
$-0.24
$-0.01
Q4 24
$0.63
Q3 24
$-0.29
$0.02
Q2 24
$-0.30
$0.03
Q1 24
$-0.29
$0.14

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRD
IRD
SIGA
SIGA
Cash + ST InvestmentsLiquidity on hand
$45.1M
$155.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$15.3M
$198.8M
Total Assets
$50.2M
$219.5M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRD
IRD
SIGA
SIGA
Q4 25
$45.1M
$155.0M
Q3 25
$30.8M
$172.0M
Q2 25
$32.4M
$182.5M
Q1 25
$41.8M
$162.3M
Q4 24
$30.3M
$155.4M
Q3 24
$36.6M
$99.3M
Q2 24
$41.4M
$106.9M
Q1 24
$47.2M
$143.9M
Stockholders' Equity
IRD
IRD
SIGA
SIGA
Q4 25
$15.3M
$198.8M
Q3 25
$6.0M
$203.5M
Q2 25
$17.5M
$209.3M
Q1 25
$5.1M
$216.1M
Q4 24
$6.7M
$215.8M
Q3 24
$34.3M
$169.4M
Q2 24
$40.6M
$167.6M
Q1 24
$46.1M
$165.0M
Total Assets
IRD
IRD
SIGA
SIGA
Q4 25
$50.2M
$219.5M
Q3 25
$36.1M
$231.6M
Q2 25
$38.7M
$235.3M
Q1 25
$48.2M
$247.1M
Q4 24
$36.9M
$244.3M
Q3 24
$40.4M
$195.4M
Q2 24
$44.8M
$192.7M
Q1 24
$51.8M
$243.1M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRD
IRD
SIGA
SIGA
Operating Cash FlowLast quarter
$-35.3M
$43.5M
Free Cash FlowOCF − Capex
$43.1M
FCF MarginFCF / Revenue
1136.4%
Capex IntensityCapex / Revenue
9.4%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$103.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRD
IRD
SIGA
SIGA
Q4 25
$-35.3M
$43.5M
Q3 25
$-6.2M
$-9.8M
Q2 25
$-10.3M
$63.1M
Q1 25
$-9.0M
$7.1M
Q4 24
$-25.6M
$56.3M
Q3 24
$-5.1M
$-7.4M
Q2 24
$-7.3M
$6.0M
Q1 24
$-5.7M
$-6.1M
Free Cash Flow
IRD
IRD
SIGA
SIGA
Q4 25
$43.1M
Q3 25
$-10.1M
Q2 25
$63.1M
Q1 25
$7.0M
Q4 24
$56.3M
Q3 24
$-7.4M
Q2 24
$6.0M
Q1 24
FCF Margin
IRD
IRD
SIGA
SIGA
Q4 25
1136.4%
Q3 25
-385.6%
Q2 25
77.8%
Q1 25
99.9%
Q4 24
69.1%
Q3 24
-74.0%
Q2 24
27.3%
Q1 24
Capex Intensity
IRD
IRD
SIGA
SIGA
Q4 25
9.4%
Q3 25
11.1%
Q2 25
0.0%
Q1 25
0.4%
Q4 24
0.0%
Q3 24
0.2%
Q2 24
0.0%
Q1 24
0.0%
Cash Conversion
IRD
IRD
SIGA
SIGA
Q4 25
Q3 25
Q2 25
1.78×
Q1 25
Q4 24
1.23×
Q3 24
-5.49×
Q2 24
3.25×
Q1 24
-0.60×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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