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Side-by-side financial comparison of Opus Genetics, Inc. (IRD) and TAKEDA PHARMACEUTICAL CO LTD (TAK). Click either name above to swap in a different company.

TAKEDA PHARMACEUTICAL CO LTD is the larger business by last-quarter revenue ($4.3M vs $3.9M, roughly 1.1× Opus Genetics, Inc.).

Opus Genetics, Inc. is a clinical-stage biotechnology company specializing in the development of targeted gene therapies for inherited retinal diseases. It focuses on addressing unmet medical needs for patients living with rare, vision-threatening ocular conditions, with operations centered on advancing accessible therapeutic candidates for global rare disease patient populations.

The Takeda Pharmaceutical Company Limited is a Japanese multinational pharmaceutical company. It is the third largest pharmaceutical company in Asia, behind Sinopharm and Shanghai Pharmaceuticals, and one of the top 20 largest pharmaceutical companies in the world by revenue. The company has over 49,578 employees worldwide and achieved US$19.299 billion in revenue during the 2018 fiscal year. The company is focused on oncology, rare diseases, neuroscience, gastroenterology, plasma-derived th...

IRD vs TAK — Head-to-Head

Bigger by revenue
TAK
TAK
1.1× larger
TAK
$4.3M
$3.9M
IRD

Income Statement — Q4 FY2025 vs Q1 FY2025

Metric
IRD
IRD
TAK
TAK
Revenue
$3.9M
$4.3M
Net Profit
$144.2K
Gross Margin
66.5%
Operating Margin
5.0%
Net Margin
3.4%
Revenue YoY
-10.2%
Net Profit YoY
53.0%
EPS (diluted)

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRD
IRD
TAK
TAK
Q4 25
$3.9M
Q3 25
$3.1M
Q2 25
$2.9M
$4.3M
Q1 25
$4.4M
Q4 24
$4.3M
Q3 24
$3.9M
Q2 24
$1.1M
Q1 24
$1.7M
$4.0M
Net Profit
IRD
IRD
TAK
TAK
Q4 25
Q3 25
$-17.5M
Q2 25
$-7.4M
$144.2K
Q1 25
$-8.2M
Q4 24
Q3 24
$-7.5M
Q2 24
$-7.8M
Q1 24
$-7.1M
$317.0K
Gross Margin
IRD
IRD
TAK
TAK
Q4 25
Q3 25
Q2 25
66.5%
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
69.1%
Operating Margin
IRD
IRD
TAK
TAK
Q4 25
Q3 25
-269.9%
Q2 25
-309.0%
5.0%
Q1 25
-227.2%
Q4 24
Q3 24
-207.1%
Q2 24
-748.9%
Q1 24
-450.5%
12.2%
Net Margin
IRD
IRD
TAK
TAK
Q4 25
Q3 25
-566.9%
Q2 25
-257.5%
3.4%
Q1 25
-187.5%
Q4 24
Q3 24
-194.6%
Q2 24
-698.3%
Q1 24
-415.3%
7.9%
EPS (diluted)
IRD
IRD
TAK
TAK
Q4 25
Q3 25
$-0.25
Q2 25
$-0.12
Q1 25
$-0.24
Q4 24
Q3 24
$-0.29
Q2 24
$-0.30
Q1 24
$-0.29

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRD
IRD
TAK
TAK
Cash + ST InvestmentsLiquidity on hand
$45.1M
$2.5B
Total DebtLower is stronger
Stockholders' EquityBook value
$15.3M
$45.1B
Total Assets
$50.2M
$92.6B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRD
IRD
TAK
TAK
Q4 25
$45.1M
Q3 25
$30.8M
Q2 25
$32.4M
$2.5B
Q1 25
$41.8M
Q4 24
$30.3M
Q3 24
$36.6M
Q2 24
$41.4M
Q1 24
$47.2M
$3.0B
Stockholders' Equity
IRD
IRD
TAK
TAK
Q4 25
$15.3M
Q3 25
$6.0M
Q2 25
$17.5M
$45.1B
Q1 25
$5.1M
Q4 24
$6.7M
Q3 24
$34.3M
Q2 24
$40.6M
Q1 24
$46.1M
$47.3B
Total Assets
IRD
IRD
TAK
TAK
Q4 25
$50.2M
Q3 25
$36.1M
Q2 25
$38.7M
$92.6B
Q1 25
$48.2M
Q4 24
$36.9M
Q3 24
$40.4M
Q2 24
$44.8M
Q1 24
$51.8M
$98.2B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRD
IRD
TAK
TAK
Operating Cash FlowLast quarter
$-35.3M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRD
IRD
TAK
TAK
Q4 25
$-35.3M
Q3 25
$-6.2M
Q2 25
$-10.3M
Q1 25
$-9.0M
Q4 24
$-25.6M
Q3 24
$-5.1M
Q2 24
$-7.3M
Q1 24
$-5.7M

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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