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Side-by-side financial comparison of IRONWOOD PHARMACEUTICALS INC (IRWD) and ON24 INC. (ONTF). Click either name above to swap in a different company.

IRONWOOD PHARMACEUTICALS INC is the larger business by last-quarter revenue ($47.7M vs $34.6M, roughly 1.4× ON24 INC.). IRONWOOD PHARMACEUTICALS INC runs the higher net margin — -4.8% vs -18.8%, a 14.0% gap on every dollar of revenue. On growth, ON24 INC. posted the faster year-over-year revenue change (-5.6% vs -47.3%). IRONWOOD PHARMACEUTICALS INC produced more free cash flow last quarter ($74.6M vs $-2.2M). Over the past eight quarters, ON24 INC.'s revenue compounded faster (-4.2% CAGR vs -20.2%).

Ironwood Pharmaceuticals, Inc. is a publicly traded pharmaceutical company. It was originally called Microbia, Inc.

ON24 Inc., a San Francisco-based company, is a cloud-based platform that develops and sells web-based webinar, virtual conferencing, content hub, and landing page applications as a service for marketing and sales teams in B2B organizations. In 2023 it expanded its offerings to include generative AI services.

IRWD vs ONTF — Head-to-Head

Bigger by revenue
IRWD
IRWD
1.4× larger
IRWD
$47.7M
$34.6M
ONTF
Growing faster (revenue YoY)
ONTF
ONTF
+41.8% gap
ONTF
-5.6%
-47.3%
IRWD
Higher net margin
IRWD
IRWD
14.0% more per $
IRWD
-4.8%
-18.8%
ONTF
More free cash flow
IRWD
IRWD
$76.8M more FCF
IRWD
$74.6M
$-2.2M
ONTF
Faster 2-yr revenue CAGR
ONTF
ONTF
Annualised
ONTF
-4.2%
-20.2%
IRWD

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
IRWD
IRWD
ONTF
ONTF
Revenue
$47.7M
$34.6M
Net Profit
$-2.3M
$-6.5M
Gross Margin
74.9%
Operating Margin
14.3%
-23.5%
Net Margin
-4.8%
-18.8%
Revenue YoY
-47.3%
-5.6%
Net Profit YoY
-200.9%
26.8%
EPS (diluted)
$0.01
$-0.15

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
IRWD
IRWD
ONTF
ONTF
Q4 25
$47.7M
$34.6M
Q3 25
$122.1M
$34.6M
Q2 25
$85.2M
$35.3M
Q1 25
$41.1M
$34.7M
Q4 24
$90.5M
$36.7M
Q3 24
$91.6M
$36.3M
Q2 24
$94.4M
$37.3M
Q1 24
$74.9M
$37.7M
Net Profit
IRWD
IRWD
ONTF
ONTF
Q4 25
$-2.3M
$-6.5M
Q3 25
$40.1M
$-6.4M
Q2 25
$23.6M
$-7.3M
Q1 25
$-37.4M
$-8.7M
Q4 24
$2.3M
$-8.9M
Q3 24
$3.6M
$-11.4M
Q2 24
$-860.0K
$-11.2M
Q1 24
$-4.2M
$-10.7M
Gross Margin
IRWD
IRWD
ONTF
ONTF
Q4 25
74.9%
Q3 25
74.7%
Q2 25
75.1%
Q1 25
73.8%
Q4 24
74.5%
Q3 24
74.3%
Q2 24
74.5%
Q1 24
74.1%
Operating Margin
IRWD
IRWD
ONTF
ONTF
Q4 25
14.3%
-23.5%
Q3 25
61.8%
-23.1%
Q2 25
53.2%
-26.0%
Q1 25
-70.7%
-30.1%
Q4 24
34.8%
-32.1%
Q3 24
28.0%
-36.7%
Q2 24
26.5%
-35.0%
Q1 24
14.7%
-33.1%
Net Margin
IRWD
IRWD
ONTF
ONTF
Q4 25
-4.8%
-18.8%
Q3 25
32.8%
-18.4%
Q2 25
27.7%
-20.6%
Q1 25
-90.9%
-25.1%
Q4 24
2.5%
-24.2%
Q3 24
4.0%
-31.4%
Q2 24
-0.9%
-29.9%
Q1 24
-5.6%
-28.4%
EPS (diluted)
IRWD
IRWD
ONTF
ONTF
Q4 25
$0.01
$-0.15
Q3 25
$0.23
$-0.15
Q2 25
$0.14
$-0.17
Q1 25
$-0.23
$-0.21
Q4 24
$0.03
$-0.21
Q3 24
$0.02
$-0.27
Q2 24
$-0.01
$-0.27
Q1 24
$-0.03
$-0.26

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
IRWD
IRWD
ONTF
ONTF
Cash + ST InvestmentsLiquidity on hand
$215.5M
$37.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$-261.8M
$139.4M
Total Assets
$396.9M
$228.4M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
IRWD
IRWD
ONTF
ONTF
Q4 25
$215.5M
$37.0M
Q3 25
$140.4M
$47.2M
Q2 25
$92.9M
$37.7M
Q1 25
$108.5M
$26.8M
Q4 24
$88.6M
$14.9M
Q3 24
$88.2M
$11.0M
Q2 24
$105.5M
$15.5M
Q1 24
$121.5M
$18.3M
Total Debt
IRWD
IRWD
ONTF
ONTF
Q4 25
Q3 25
$199.5M
Q2 25
$199.3M
Q1 25
$199.2M
Q4 24
$199.0M
Q3 24
$198.8M
Q2 24
$198.6M
Q1 24
$398.3M
Stockholders' Equity
IRWD
IRWD
ONTF
ONTF
Q4 25
$-261.8M
$139.4M
Q3 25
$-264.2M
$144.3M
Q2 25
$-308.2M
$150.0M
Q1 25
$-334.1M
$153.7M
Q4 24
$-301.3M
$159.4M
Q3 24
$-311.3M
$164.9M
Q2 24
$-321.7M
$170.8M
Q1 24
$-330.5M
$174.4M
Total Assets
IRWD
IRWD
ONTF
ONTF
Q4 25
$396.9M
$228.4M
Q3 25
$396.1M
$224.8M
Q2 25
$342.9M
$235.1M
Q1 25
$327.2M
$245.8M
Q4 24
$350.9M
$251.0M
Q3 24
$389.5M
$250.9M
Q2 24
$395.6M
$259.0M
Q1 24
$438.8M
$269.2M

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
IRWD
IRWD
ONTF
ONTF
Operating Cash FlowLast quarter
$74.6M
$-1.1M
Free Cash FlowOCF − Capex
$74.6M
$-2.2M
FCF MarginFCF / Revenue
156.3%
-6.4%
Capex IntensityCapex / Revenue
0.0%
3.3%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$127.0M
$4.0M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
IRWD
IRWD
ONTF
ONTF
Q4 25
$74.6M
$-1.1M
Q3 25
$47.6M
$2.5M
Q2 25
$-15.1M
$2.6M
Q1 25
$20.0M
$3.4M
Q4 24
$15.2M
$985.0K
Q3 24
$9.9M
$295.0K
Q2 24
$33.5M
$1.4M
Q1 24
$45.0M
$2.1M
Free Cash Flow
IRWD
IRWD
ONTF
ONTF
Q4 25
$74.6M
$-2.2M
Q3 25
$47.6M
$2.2M
Q2 25
$-15.1M
$2.1M
Q1 25
$19.9M
$1.9M
Q4 24
$424.0K
Q3 24
$9.9M
$143.0K
Q2 24
$33.4M
$898.0K
Q1 24
$44.9M
$1.1M
FCF Margin
IRWD
IRWD
ONTF
ONTF
Q4 25
156.3%
-6.4%
Q3 25
39.0%
6.2%
Q2 25
-17.7%
5.9%
Q1 25
48.4%
5.6%
Q4 24
1.2%
Q3 24
10.8%
0.4%
Q2 24
35.4%
2.4%
Q1 24
60.0%
2.9%
Capex Intensity
IRWD
IRWD
ONTF
ONTF
Q4 25
0.0%
3.3%
Q3 25
0.0%
1.1%
Q2 25
0.0%
1.4%
Q1 25
0.1%
4.2%
Q4 24
0.0%
1.5%
Q3 24
0.0%
0.4%
Q2 24
0.1%
1.3%
Q1 24
0.1%
2.8%
Cash Conversion
IRWD
IRWD
ONTF
ONTF
Q4 25
Q3 25
1.19×
Q2 25
-0.64×
Q1 25
Q4 24
6.74×
Q3 24
2.71×
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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