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Side-by-side financial comparison of Intuitive Surgical (ISRG) and XPO, Inc. (XPO). Click either name above to swap in a different company.

Intuitive Surgical is the larger business by last-quarter revenue ($2.8B vs $2.0B, roughly 1.4× XPO, Inc.). Intuitive Surgical runs the higher net margin — 29.8% vs 2.9%, a 26.9% gap on every dollar of revenue. On growth, Intuitive Surgical posted the faster year-over-year revenue change (23.0% vs 4.7%). Over the past eight quarters, Intuitive Surgical's revenue compounded faster (17.4% CAGR vs -0.1%).

Intuitive Surgical, Inc. is an American biotechnology company that develops, manufactures, and markets robotic products designed to improve clinical outcomes of patients through minimally invasive surgery, most notably with the da Vinci Surgical System. The company is part of the Nasdaq-100, S&P 100 and S&P 500. As of 31 December 2021, Intuitive Surgical had an installed base of 6,730 da Vinci Surgical Systems, including 4,139 in the U.S.

XPO, Inc., formerly XPO Logistics, is an American transportation company that conducts less-than-truckload shipping in North America. The company has headquarters in Greenwich, Connecticut, and has 592 locations globally. XPO is the second largest provider of less-than-truckload (LTL) services in North America, operating in 99 percent of all U.S. postal codes.

ISRG vs XPO — Head-to-Head

Bigger by revenue
ISRG
ISRG
1.4× larger
ISRG
$2.8B
$2.0B
XPO
Growing faster (revenue YoY)
ISRG
ISRG
+18.3% gap
ISRG
23.0%
4.7%
XPO
Higher net margin
ISRG
ISRG
26.9% more per $
ISRG
29.8%
2.9%
XPO
Faster 2-yr revenue CAGR
ISRG
ISRG
Annualised
ISRG
17.4%
-0.1%
XPO

Income Statement — Q1 FY2026 vs Q4 FY2025

Metric
ISRG
ISRG
XPO
XPO
Revenue
$2.8B
$2.0B
Net Profit
$826.0M
$59.0M
Gross Margin
66.1%
Operating Margin
7.1%
Net Margin
29.8%
2.9%
Revenue YoY
23.0%
4.7%
Net Profit YoY
17.4%
-21.3%
EPS (diluted)
$2.28
$0.49

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
ISRG
ISRG
XPO
XPO
Q1 26
$2.8B
Q4 25
$2.9B
$2.0B
Q3 25
$2.5B
$2.1B
Q2 25
$2.4B
$2.1B
Q1 25
$2.3B
$2.0B
Q4 24
$2.4B
$1.9B
Q3 24
$2.0B
$2.1B
Q2 24
$2.0B
$2.1B
Net Profit
ISRG
ISRG
XPO
XPO
Q1 26
$826.0M
Q4 25
$794.8M
$59.0M
Q3 25
$704.4M
$82.0M
Q2 25
$658.4M
$106.0M
Q1 25
$698.4M
$69.0M
Q4 24
$685.7M
$75.0M
Q3 24
$565.1M
$95.0M
Q2 24
$526.9M
$150.0M
Gross Margin
ISRG
ISRG
XPO
XPO
Q1 26
66.1%
Q4 25
66.4%
Q3 25
66.4%
Q2 25
66.3%
Q1 25
64.7%
Q4 24
68.0%
Q3 24
67.4%
Q2 24
68.3%
Operating Margin
ISRG
ISRG
XPO
XPO
Q1 26
Q4 25
30.2%
7.1%
Q3 25
30.3%
7.8%
Q2 25
30.5%
9.5%
Q1 25
25.7%
7.7%
Q4 24
30.4%
7.8%
Q3 24
28.3%
8.6%
Q2 24
28.2%
9.5%
Net Margin
ISRG
ISRG
XPO
XPO
Q1 26
29.8%
Q4 25
27.7%
2.9%
Q3 25
28.1%
3.9%
Q2 25
27.0%
5.1%
Q1 25
31.0%
3.5%
Q4 24
28.4%
3.9%
Q3 24
27.7%
4.6%
Q2 24
26.2%
7.2%
EPS (diluted)
ISRG
ISRG
XPO
XPO
Q1 26
$2.28
Q4 25
$2.19
$0.49
Q3 25
$1.95
$0.68
Q2 25
$1.81
$0.89
Q1 25
$1.92
$0.58
Q4 24
$1.89
$0.63
Q3 24
$1.56
$0.79
Q2 24
$1.46
$1.25

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
ISRG
ISRG
XPO
XPO
Cash + ST InvestmentsLiquidity on hand
$310.0M
Total DebtLower is stronger
Stockholders' EquityBook value
$17.6B
$1.9B
Total Assets
$20.1B
$8.2B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
ISRG
ISRG
XPO
XPO
Q1 26
Q4 25
$5.9B
$310.0M
Q3 25
$4.9B
$335.0M
Q2 25
$5.3B
$225.0M
Q1 25
$4.5B
$212.0M
Q4 24
$4.0B
$246.0M
Q3 24
$4.2B
$378.0M
Q2 24
$4.8B
$250.0M
Stockholders' Equity
ISRG
ISRG
XPO
XPO
Q1 26
$17.6B
Q4 25
$17.8B
$1.9B
Q3 25
$16.9B
$1.8B
Q2 25
$17.8B
$1.8B
Q1 25
$17.1B
$1.6B
Q4 24
$16.4B
$1.6B
Q3 24
$15.6B
$1.6B
Q2 24
$14.7B
$1.5B
Total Assets
ISRG
ISRG
XPO
XPO
Q1 26
$20.1B
Q4 25
$20.5B
$8.2B
Q3 25
$19.4B
$8.2B
Q2 25
$20.2B
$8.1B
Q1 25
$19.2B
$7.9B
Q4 24
$18.7B
$7.7B
Q3 24
$17.7B
$7.9B
Q2 24
$16.6B
$7.7B

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

ISRG
ISRG

Instruments and accessories$1.7B61%
Systems$650.7M23%
Services$433.7M16%

XPO
XPO

North American LTL$1.2B58%
European Transportation$844.0M42%

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