vs
Side-by-side financial comparison of Karyopharm Therapeutics Inc. (KPTI) and Star Equity Holdings, Inc. (STRR). Click either name above to swap in a different company.
Star Equity Holdings, Inc. is the larger business by last-quarter revenue ($56.8M vs $34.1M, roughly 1.7× Karyopharm Therapeutics Inc.). Star Equity Holdings, Inc. runs the higher net margin — -3.0% vs -299.9%, a 296.9% gap on every dollar of revenue. On growth, Star Equity Holdings, Inc. posted the faster year-over-year revenue change (69.0% vs 11.6%). Over the past eight quarters, Star Equity Holdings, Inc.'s revenue compounded faster (29.5% CAGR vs 1.4%).
Artists Equity is an American production company founded by actors and filmmakers Ben Affleck and Matt Damon in November 2022.
KPTI vs STRR — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $34.1M | $56.8M |
| Net Profit | $-102.2M | $-1.7M |
| Gross Margin | — | — |
| Operating Margin | -52.4% | -0.2% |
| Net Margin | -299.9% | -3.0% |
| Revenue YoY | 11.6% | 69.0% |
| Net Profit YoY | -232.0% | -192.1% |
| EPS (diluted) | $-7.02 | $-0.49 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $34.1M | $56.8M | ||
| Q3 25 | $44.0M | $48.0M | ||
| Q2 25 | $37.9M | $35.5M | ||
| Q1 25 | $30.0M | $31.9M | ||
| Q4 24 | $30.5M | $33.6M | ||
| Q3 24 | $38.8M | $36.9M | ||
| Q2 24 | $42.8M | $35.7M | ||
| Q1 24 | $33.1M | $33.9M |
| Q4 25 | $-102.2M | $-1.7M | ||
| Q3 25 | $-33.1M | $-1.8M | ||
| Q2 25 | $-37.3M | $-688.0K | ||
| Q1 25 | $-23.5M | $-1.8M | ||
| Q4 24 | $-30.8M | $-585.0K | ||
| Q3 24 | $-32.1M | $-846.0K | ||
| Q2 24 | $23.8M | $-441.0K | ||
| Q1 24 | $-37.4M | $-2.9M |
| Q4 25 | — | — | ||
| Q3 25 | — | 43.0% | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | 50.5% | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | -52.4% | -0.2% | ||
| Q3 25 | -34.6% | -3.4% | ||
| Q2 25 | -64.3% | -0.6% | ||
| Q1 25 | -110.8% | -5.4% | ||
| Q4 24 | -102.4% | -0.4% | ||
| Q3 24 | -67.8% | -1.2% | ||
| Q2 24 | -65.7% | -0.5% | ||
| Q1 24 | -101.9% | -9.0% |
| Q4 25 | -299.9% | -3.0% | ||
| Q3 25 | -75.2% | -3.7% | ||
| Q2 25 | -98.2% | -1.9% | ||
| Q1 25 | -78.2% | -5.5% | ||
| Q4 24 | -100.8% | -1.7% | ||
| Q3 24 | -82.7% | -2.3% | ||
| Q2 24 | 55.6% | -1.2% | ||
| Q1 24 | -112.8% | -8.6% |
| Q4 25 | $-7.02 | $-0.49 | ||
| Q3 25 | $-3.82 | $-0.54 | ||
| Q2 25 | $-4.32 | $-0.23 | ||
| Q1 25 | $-2.77 | $-0.59 | ||
| Q4 24 | $-2.33 | $-0.21 | ||
| Q3 24 | $-3.85 | $-0.28 | ||
| Q2 24 | $-2.97 | $-0.15 | ||
| Q1 24 | $-4.85 | $-0.95 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $60.5M | $10.3M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $-292.9M | $65.7M |
| Total Assets | $108.4M | $113.2M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $60.5M | $10.3M | ||
| Q3 25 | $37.7M | $15.4M | ||
| Q2 25 | $38.7M | $16.8M | ||
| Q1 25 | $38.8M | $16.6M | ||
| Q4 24 | $62.5M | $17.0M | ||
| Q3 24 | $72.8M | $15.8M | ||
| Q2 24 | $84.8M | $14.7M | ||
| Q1 24 | $30.6M | $20.4M |
| Q4 25 | — | — | ||
| Q3 25 | — | $6.5M | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | $0 | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
| Q4 25 | $-292.9M | $65.7M | ||
| Q3 25 | $-269.3M | $67.8M | ||
| Q2 25 | $-238.9M | $40.1M | ||
| Q1 25 | $-205.9M | $39.5M | ||
| Q4 24 | $-186.0M | $40.4M | ||
| Q3 24 | $-159.6M | $42.9M | ||
| Q2 24 | $-132.1M | $42.6M | ||
| Q1 24 | $-169.0M | $44.3M |
| Q4 25 | $108.4M | $113.2M | ||
| Q3 25 | $96.2M | $117.1M | ||
| Q2 25 | $104.9M | $55.6M | ||
| Q1 25 | $127.7M | $53.2M | ||
| Q4 24 | $164.4M | $52.6M | ||
| Q3 24 | $189.5M | $52.6M | ||
| Q2 24 | $214.0M | $52.6M | ||
| Q1 24 | $204.5M | $52.6M |
| Q4 25 | — | — | ||
| Q3 25 | — | 0.10× | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | 0.00× | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-11.8M | $-7.3M |
| Free Cash FlowOCF − Capex | — | $-9.0M |
| FCF MarginFCF / Revenue | — | -15.8% |
| Capex IntensityCapex / Revenue | 0.0% | 3.0% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $-13.0M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-11.8M | $-7.3M | ||
| Q3 25 | $-5.9M | $-2.7M | ||
| Q2 25 | $-18.7M | $139.0K | ||
| Q1 25 | $-39.0M | $-802.0K | ||
| Q4 24 | $-25.8M | $-2.8M | ||
| Q3 24 | $-19.5M | $1.3M | ||
| Q2 24 | $-38.5M | $-4.3M | ||
| Q1 24 | $-43.7M | $-1.8M |
| Q4 25 | — | $-9.0M | ||
| Q3 25 | — | $-3.4M | ||
| Q2 25 | — | $102.0K | ||
| Q1 25 | — | $-808.0K | ||
| Q4 24 | $-25.9M | $-2.8M | ||
| Q3 24 | — | $1.3M | ||
| Q2 24 | — | $-4.3M | ||
| Q1 24 | $-43.9M | $-1.8M |
| Q4 25 | — | -15.8% | ||
| Q3 25 | — | -7.0% | ||
| Q2 25 | — | 0.3% | ||
| Q1 25 | — | -2.5% | ||
| Q4 24 | -84.7% | -8.3% | ||
| Q3 24 | — | 3.4% | ||
| Q2 24 | — | -12.0% | ||
| Q1 24 | -132.6% | -5.3% |
| Q4 25 | 0.0% | 3.0% | ||
| Q3 25 | 0.0% | 1.3% | ||
| Q2 25 | 0.0% | 0.1% | ||
| Q1 25 | 0.0% | 0.0% | ||
| Q4 24 | 0.2% | 0.1% | ||
| Q3 24 | 0.0% | 0.0% | ||
| Q2 24 | 0.0% | 0.0% | ||
| Q1 24 | 0.6% | 0.0% |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | -1.62× | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
KPTI
| Products | $32.1M | 94% |
| License And Other | $2.0M | 6% |
STRR
| Revenue From Other Contracts With Customers | $27.6M | 49% |
| Other | $24.3M | 43% |
| Energy Services Segment | $4.9M | 9% |
