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Side-by-side financial comparison of Lineage Cell Therapeutics, Inc. (LCTX) and Taysha Gene Therapies, Inc. (TSHA). Click either name above to swap in a different company.
Lineage Cell Therapeutics, Inc. is the larger business by last-quarter revenue ($6.6M vs $5.5M, roughly 1.2× Taysha Gene Therapies, Inc.). Lineage Cell Therapeutics, Inc. runs the higher net margin — 12.9% vs -507.8%, a 520.6% gap on every dollar of revenue. On growth, Taysha Gene Therapies, Inc. posted the faster year-over-year revenue change (171.3% vs 130.4%). Over the past eight quarters, Lineage Cell Therapeutics, Inc.'s revenue compounded faster (113.9% CAGR vs 26.8%).
Lineage Cell Therapeutics, Inc. is a clinical-stage biotechnology company developing novel cell therapies for unmet medical needs. Lineage’s programs are based on its robust proprietary cell-based therapy platform and associated in-house development and manufacturing capabilities. With this platform, Lineage develops and manufactures specialized, terminally differentiated human cells from its pluripotent and progenitor cell starting materials. These differentiated cells are developed to eithe...
Taysha Gene Therapies, Inc. is a clinical-stage biotechnology company specializing in developing adeno-associated virus (AAV)-based gene therapies for rare monogenic central nervous system disorders with high unmet medical needs. Its core pipeline targets serious life-threatening neurological conditions, with primary operations and market focus across North America and European regions.
LCTX vs TSHA — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $6.6M | $5.5M |
| Net Profit | $851.0K | $-27.9M |
| Gross Margin | — | — |
| Operating Margin | -99.1% | -516.0% |
| Net Margin | 12.9% | -507.8% |
| Revenue YoY | 130.4% | 171.3% |
| Net Profit YoY | 126.0% | -48.3% |
| EPS (diluted) | $0.00 | $-0.08 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $6.6M | $5.5M | ||
| Q3 25 | $3.7M | $0 | ||
| Q2 25 | $2.8M | $2.0M | ||
| Q1 25 | $1.5M | $2.3M | ||
| Q4 24 | $2.9M | $2.0M | ||
| Q3 24 | $3.8M | $1.8M | ||
| Q2 24 | $1.4M | $1.1M | ||
| Q1 24 | $1.4M | $3.4M |
| Q4 25 | $851.0K | $-27.9M | ||
| Q3 25 | $-29.8M | $-32.7M | ||
| Q2 25 | $-30.5M | $-26.9M | ||
| Q1 25 | $-4.1M | $-21.5M | ||
| Q4 24 | $-3.3M | $-18.8M | ||
| Q3 24 | $-3.0M | $-25.5M | ||
| Q2 24 | $-5.8M | $-20.9M | ||
| Q1 24 | $-6.5M | $-24.1M |
| Q4 25 | — | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | 97.6% | — | ||
| Q4 24 | 94.6% | — | ||
| Q3 24 | 99.0% | — | ||
| Q2 24 | 96.9% | — | ||
| Q1 24 | 93.2% | — |
| Q4 25 | -99.1% | -516.0% | ||
| Q3 25 | -102.9% | — | ||
| Q2 25 | -715.4% | -1347.1% | ||
| Q1 25 | -433.1% | -930.5% | ||
| Q4 24 | -178.2% | -985.8% | ||
| Q3 24 | -101.6% | -1448.4% | ||
| Q2 24 | -416.7% | -1915.4% | ||
| Q1 24 | -461.3% | -713.3% |
| Q4 25 | 12.9% | -507.8% | ||
| Q3 25 | -809.0% | — | ||
| Q2 25 | -1101.8% | -1353.6% | ||
| Q1 25 | -275.6% | -935.2% | ||
| Q4 24 | -114.1% | -929.0% | ||
| Q3 24 | -80.3% | -1427.5% | ||
| Q2 24 | -409.1% | -1882.0% | ||
| Q1 24 | -453.0% | -705.4% |
| Q4 25 | $0.00 | $-0.08 | ||
| Q3 25 | $-0.13 | $-0.09 | ||
| Q2 25 | $-0.13 | $-0.09 | ||
| Q1 25 | $-0.02 | $-0.08 | ||
| Q4 24 | $0.00 | $-0.07 | ||
| Q3 24 | $-0.02 | $-0.10 | ||
| Q2 24 | $-0.03 | $-0.09 | ||
| Q1 24 | $-0.04 | $-0.10 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $55.8M | $319.8M |
| Total DebtLower is stronger | — | — |
| Stockholders' EquityBook value | $44.5M | $246.9M |
| Total Assets | $112.6M | $343.3M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $55.8M | $319.8M | ||
| Q3 25 | $40.5M | $297.3M | ||
| Q2 25 | $42.3M | $312.8M | ||
| Q1 25 | $47.9M | $116.6M | ||
| Q4 24 | $47.8M | $139.0M | ||
| Q3 24 | $32.7M | $157.7M | ||
| Q2 24 | $38.5M | $172.7M | ||
| Q1 24 | $43.6M | $124.0M |
| Q4 25 | $44.5M | $246.9M | ||
| Q3 25 | $22.0M | $219.0M | ||
| Q2 25 | $48.4M | $248.7M | ||
| Q1 25 | $79.0M | $55.1M | ||
| Q4 24 | $78.4M | $71.5M | ||
| Q3 24 | $66.2M | $88.8M | ||
| Q2 24 | $68.3M | $108.9M | ||
| Q1 24 | $72.4M | $53.8M |
| Q4 25 | $112.6M | $343.3M | ||
| Q3 25 | $89.6M | $316.6M | ||
| Q2 25 | $90.8M | $333.3M | ||
| Q1 25 | $111.8M | $138.4M | ||
| Q4 24 | $113.2M | $160.4M | ||
| Q3 24 | $96.6M | $180.2M | ||
| Q2 24 | $102.8M | $200.4M | ||
| Q1 24 | $108.5M | $153.0M |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-4.9M | $-26.7M |
| Free Cash FlowOCF − Capex | $-5.3M | — |
| FCF MarginFCF / Revenue | -79.9% | — |
| Capex IntensityCapex / Revenue | 6.0% | — |
| Cash ConversionOCF / Net Profit | -5.73× | — |
| TTM Free Cash FlowTrailing 4 quarters | $-19.4M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-4.9M | $-26.7M | ||
| Q3 25 | $-3.6M | $-24.2M | ||
| Q2 25 | $-5.5M | $-20.2M | ||
| Q1 25 | $-4.9M | $-22.0M | ||
| Q4 24 | $-6.3M | $-18.3M | ||
| Q3 24 | $-5.8M | $-21.6M | ||
| Q2 24 | $-5.2M | $-21.5M | ||
| Q1 24 | $-5.8M | $-19.8M |
| Q4 25 | $-5.3M | — | ||
| Q3 25 | $-3.6M | $-24.3M | ||
| Q2 25 | $-5.6M | — | ||
| Q1 25 | $-5.0M | — | ||
| Q4 24 | $-6.7M | $-18.3M | ||
| Q3 24 | $-5.9M | $-21.6M | ||
| Q2 24 | $-5.2M | $-21.7M | ||
| Q1 24 | $-5.8M | $-19.9M |
| Q4 25 | -79.9% | — | ||
| Q3 25 | -98.6% | — | ||
| Q2 25 | -200.8% | — | ||
| Q1 25 | -331.8% | — | ||
| Q4 24 | -234.0% | -905.5% | ||
| Q3 24 | -156.1% | -1210.9% | ||
| Q2 24 | -371.2% | -1951.9% | ||
| Q1 24 | -403.1% | -584.5% |
| Q4 25 | 6.0% | — | ||
| Q3 25 | 0.3% | — | ||
| Q2 25 | 0.5% | — | ||
| Q1 25 | 6.5% | — | ||
| Q4 24 | 12.7% | 0.1% | ||
| Q3 24 | 3.0% | 2.0% | ||
| Q2 24 | 3.6% | 18.1% | ||
| Q1 24 | 2.6% | 4.1% |
| Q4 25 | -5.73× | — | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | — | ||
| Q4 24 | — | — | ||
| Q3 24 | — | — | ||
| Q2 24 | — | — | ||
| Q1 24 | — | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
LCTX
| Collaboration Revenues | $6.3M | 95% |
| Other | $345.0K | 5% |
TSHA
Segment breakdown not available.
