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Side-by-side financial comparison of LIGAND PHARMACEUTICALS INC (LGND) and SOUTHERN FIRST BANCSHARES INC (SFST). Click either name above to swap in a different company.

LIGAND PHARMACEUTICALS INC is the larger business by last-quarter revenue ($59.7M vs $31.8M, roughly 1.9× SOUTHERN FIRST BANCSHARES INC). On growth, LIGAND PHARMACEUTICALS INC posted the faster year-over-year revenue change (39.4% vs 26.1%). LIGAND PHARMACEUTICALS INC produced more free cash flow last quarter ($45.9M vs $29.9M). Over the past eight quarters, LIGAND PHARMACEUTICALS INC's revenue compounded faster (38.8% CAGR vs 22.2%).

Ligand Pharmaceuticals is an American biopharmaceutical company that focuses on acquiring and developing royalty-generating assets. As of 2024, the company's portfolio included royalty rights to approximately 90 pharmaceutical products across a range of therapeutic areas. Notable products from which Ligand receives royalties include the multiple myeloma (cancer) treatments Kyprolis and Evomela, the kidney disease therapy Filspari, and the pneumococcal vaccine Vaxneuvance. The company also own...

First Community Bankshares, Inc. is a $2.43 billion bank holding company and the parent company of First Community Bank of Bluefield, Virginia, in the United States. As of 2012 First Community Bank had 45 locations in Virginia, West Virginia, and North Carolina, and two locations operating as Peoples Community Bank in Tennessee. As of April 21, 2023, First Community had $3.6 billion in assets.

LGND vs SFST — Head-to-Head

Bigger by revenue
LGND
LGND
1.9× larger
LGND
$59.7M
$31.8M
SFST
Growing faster (revenue YoY)
LGND
LGND
+13.2% gap
LGND
39.4%
26.1%
SFST
More free cash flow
LGND
LGND
$16.0M more FCF
LGND
$45.9M
$29.9M
SFST
Faster 2-yr revenue CAGR
LGND
LGND
Annualised
LGND
38.8%
22.2%
SFST

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
LGND
LGND
SFST
SFST
Revenue
$59.7M
$31.8M
Net Profit
$44.8M
Gross Margin
Operating Margin
23.2%
40.1%
Net Margin
75.1%
Revenue YoY
39.4%
26.1%
Net Profit YoY
244.1%
EPS (diluted)
$2.42
$1.19

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
LGND
LGND
SFST
SFST
Q4 25
$59.7M
$31.8M
Q3 25
$115.5M
$31.1M
Q2 25
$47.6M
$28.6M
Q1 25
$45.3M
$26.5M
Q4 24
$42.8M
$25.2M
Q3 24
$51.8M
$23.8M
Q2 24
$41.5M
$23.1M
Q1 24
$31.0M
$21.3M
Net Profit
LGND
LGND
SFST
SFST
Q4 25
$44.8M
Q3 25
$117.3M
$8.7M
Q2 25
$4.8M
$6.6M
Q1 25
$-42.5M
$5.3M
Q4 24
$-31.1M
Q3 24
$-7.2M
$4.4M
Q2 24
$-51.9M
$3.0M
Q1 24
$86.1M
$2.5M
Operating Margin
LGND
LGND
SFST
SFST
Q4 25
23.2%
40.1%
Q3 25
47.6%
36.4%
Q2 25
17.7%
30.0%
Q1 25
-79.9%
26.1%
Q4 24
-22.5%
27.3%
Q3 24
6.1%
24.1%
Q2 24
-46.0%
17.0%
Q1 24
9.6%
15.9%
Net Margin
LGND
LGND
SFST
SFST
Q4 25
75.1%
Q3 25
101.6%
27.8%
Q2 25
10.2%
23.0%
Q1 25
-93.6%
19.9%
Q4 24
-72.6%
Q3 24
-13.8%
18.4%
Q2 24
-125.0%
13.0%
Q1 24
278.1%
11.8%
EPS (diluted)
LGND
LGND
SFST
SFST
Q4 25
$2.42
$1.19
Q3 25
$5.68
$1.07
Q2 25
$0.24
$0.81
Q1 25
$-2.21
$0.65
Q4 24
$-1.70
$0.69
Q3 24
$-0.39
$0.54
Q2 24
$-2.88
$0.37
Q1 24
$4.75
$0.31

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
LGND
LGND
SFST
SFST
Cash + ST InvestmentsLiquidity on hand
$733.5M
Total DebtLower is stronger
Stockholders' EquityBook value
$1.0B
$368.7M
Total Assets
$1.6B
$4.4B
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
LGND
LGND
SFST
SFST
Q4 25
$733.5M
Q3 25
$664.5M
Q2 25
$245.0M
Q1 25
$208.9M
Q4 24
$256.2M
Q3 24
$219.6M
Q2 24
$226.9M
Q1 24
$310.6M
Stockholders' Equity
LGND
LGND
SFST
SFST
Q4 25
$1.0B
$368.7M
Q3 25
$950.2M
$356.3M
Q2 25
$828.5M
$345.5M
Q1 25
$795.5M
$337.6M
Q4 24
$830.4M
$330.4M
Q3 24
$841.2M
$326.5M
Q2 24
$775.2M
$318.7M
Q1 24
$806.5M
$315.3M
Total Assets
LGND
LGND
SFST
SFST
Q4 25
$1.6B
$4.4B
Q3 25
$1.5B
$4.4B
Q2 25
$948.6M
$4.3B
Q1 25
$905.4M
$4.3B
Q4 24
$941.8M
$4.1B
Q3 24
$954.9M
$4.2B
Q2 24
$866.4M
$4.1B
Q1 24
$913.9M
$4.1B

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
LGND
LGND
SFST
SFST
Operating Cash FlowLast quarter
$45.9M
$30.5M
Free Cash FlowOCF − Capex
$45.9M
$29.9M
FCF MarginFCF / Revenue
76.9%
93.8%
Capex IntensityCapex / Revenue
0.0%
1.8%
Cash ConversionOCF / Net Profit
1.03×
TTM Free Cash FlowTrailing 4 quarters
$48.9M
$62.1M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
LGND
LGND
SFST
SFST
Q4 25
$45.9M
$30.5M
Q3 25
$13.1M
$14.5M
Q2 25
$15.8M
$10.5M
Q1 25
$-25.4M
$7.6M
Q4 24
$28.5M
$25.6M
Q3 24
$36.5M
$26.3M
Q2 24
$13.3M
$4.0M
Q1 24
$18.7M
$-2.9M
Free Cash Flow
LGND
LGND
SFST
SFST
Q4 25
$45.9M
$29.9M
Q3 25
$13.1M
$14.4M
Q2 25
$15.6M
$10.4M
Q1 25
$-25.7M
$7.4M
Q4 24
$27.8M
$24.8M
Q3 24
$35.9M
$26.1M
Q2 24
$12.9M
$3.9M
Q1 24
$18.6M
$-3.2M
FCF Margin
LGND
LGND
SFST
SFST
Q4 25
76.9%
93.8%
Q3 25
11.3%
46.3%
Q2 25
32.7%
36.3%
Q1 25
-56.6%
28.1%
Q4 24
64.8%
98.2%
Q3 24
69.4%
110.0%
Q2 24
31.1%
16.8%
Q1 24
60.1%
-15.0%
Capex Intensity
LGND
LGND
SFST
SFST
Q4 25
0.0%
1.8%
Q3 25
0.0%
0.3%
Q2 25
0.4%
0.3%
Q1 25
0.5%
0.5%
Q4 24
1.7%
3.1%
Q3 24
1.2%
0.8%
Q2 24
1.0%
0.4%
Q1 24
0.3%
1.3%
Cash Conversion
LGND
LGND
SFST
SFST
Q4 25
1.03×
Q3 25
0.11×
1.67×
Q2 25
3.26×
1.59×
Q1 25
1.44×
Q4 24
Q3 24
6.01×
Q2 24
1.32×
Q1 24
0.22×
-1.16×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

LGND
LGND

Intangible Royalty Assets$40.7M68%
Financial Royalty Assets$9.8M16%
Material Sales Captisol$7.8M13%
Vaxneuvance$1.4M2%

SFST
SFST

Segment breakdown not available.

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