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Side-by-side financial comparison of Lake Shore Bancorp, Inc. (LSBK) and Nurix Therapeutics, Inc. (NRIX). Click either name above to swap in a different company.

Nurix Therapeutics, Inc. is the larger business by last-quarter revenue ($13.6M vs $7.4M, roughly 1.8× Lake Shore Bancorp, Inc.). Lake Shore Bancorp, Inc. runs the higher net margin — 31.8% vs -576.1%, a 607.9% gap on every dollar of revenue. Lake Shore Bancorp, Inc. produced more free cash flow last quarter ($3.3M vs $-73.0M).

Lake Shore Bancorp, Inc. (Maryland) is a U.S. regional bank holding company that operates via its banking subsidiary, offering retail and commercial banking services including deposits, loans, mortgages and wealth management, primarily serving individuals and SMEs across local communities in Maryland.

Nurix Therapeutics, Inc. is a clinical-stage biopharmaceutical company focused on discovering, developing and commercializing novel targeted protein degradation therapies for cancer, immune disorders and other serious unmet medical needs. Its core pipeline leverages proprietary E3 ubiquitin ligase modulation technology, with operations primarily based in the United States and collaborative partnerships with global pharmaceutical firms.

LSBK vs NRIX — Head-to-Head

Bigger by revenue
NRIX
NRIX
1.8× larger
NRIX
$13.6M
$7.4M
LSBK
Higher net margin
LSBK
LSBK
607.9% more per $
LSBK
31.8%
-576.1%
NRIX
More free cash flow
LSBK
LSBK
$76.3M more FCF
LSBK
$3.3M
$-73.0M
NRIX

Income Statement — Q3 FY2025 vs Q4 FY2025

Metric
LSBK
LSBK
NRIX
NRIX
Revenue
$7.4M
$13.6M
Net Profit
$2.4M
$-78.2M
Gross Margin
Operating Margin
38.4%
-612.0%
Net Margin
31.8%
-576.1%
Revenue YoY
2.2%
Net Profit YoY
-33.6%
EPS (diluted)
$0.32
$-0.83

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
LSBK
LSBK
NRIX
NRIX
Q4 25
$13.6M
Q3 25
$7.4M
$7.9M
Q2 25
$6.9M
$44.1M
Q1 25
$18.5M
Q4 24
$13.3M
Q3 24
$12.6M
Q2 24
$12.1M
Q1 24
$16.6M
Net Profit
LSBK
LSBK
NRIX
NRIX
Q4 25
$-78.2M
Q3 25
$2.4M
$-86.4M
Q2 25
$1.9M
$-43.5M
Q1 25
$-56.4M
Q4 24
$-58.5M
Q3 24
$-49.0M
Q2 24
$-44.5M
Q1 24
$-41.5M
Operating Margin
LSBK
LSBK
NRIX
NRIX
Q4 25
-612.0%
Q3 25
38.4%
-1157.7%
Q2 25
33.2%
-109.7%
Q1 25
-340.7%
Q4 24
-486.7%
Q3 24
-433.8%
Q2 24
-401.4%
Q1 24
-272.6%
Net Margin
LSBK
LSBK
NRIX
NRIX
Q4 25
-576.1%
Q3 25
31.8%
-1094.8%
Q2 25
27.7%
-98.7%
Q1 25
-305.4%
Q4 24
-440.7%
Q3 24
-388.9%
Q2 24
-368.4%
Q1 24
-250.3%
EPS (diluted)
LSBK
LSBK
NRIX
NRIX
Q4 25
$-0.83
Q3 25
$0.32
$-1.03
Q2 25
$0.34
$-0.52
Q1 25
$-0.67
Q4 24
$-0.74
Q3 24
$-0.67
Q2 24
$-0.71
Q1 24
$-0.76

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
LSBK
LSBK
NRIX
NRIX
Cash + ST InvestmentsLiquidity on hand
$83.6M
$247.0M
Total DebtLower is stronger
$2.0M
Stockholders' EquityBook value
$139.3M
$538.7M
Total Assets
$742.8M
$688.1M
Debt / EquityLower = less leverage
0.01×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
LSBK
LSBK
NRIX
NRIX
Q4 25
$247.0M
Q3 25
$83.6M
$78.4M
Q2 25
$75.4M
$84.3M
Q1 25
$75.9M
Q4 24
$110.0M
Q3 24
$99.0M
Q2 24
$116.8M
Q1 24
$49.8M
Total Debt
LSBK
LSBK
NRIX
NRIX
Q4 25
Q3 25
$2.0M
Q2 25
$2.0M
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24
Stockholders' Equity
LSBK
LSBK
NRIX
NRIX
Q4 25
$538.7M
Q3 25
$139.3M
$372.3M
Q2 25
$92.9M
$447.6M
Q1 25
$480.9M
Q4 24
$527.0M
Q3 24
$376.9M
Q2 24
$370.7M
Q1 24
$168.7M
Total Assets
LSBK
LSBK
NRIX
NRIX
Q4 25
$688.1M
Q3 25
$742.8M
$522.5M
Q2 25
$734.8M
$591.6M
Q1 25
$615.0M
Q4 24
$669.3M
Q3 24
$513.6M
Q2 24
$511.0M
Q1 24
$312.7M
Debt / Equity
LSBK
LSBK
NRIX
NRIX
Q4 25
Q3 25
0.01×
Q2 25
0.02×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
LSBK
LSBK
NRIX
NRIX
Operating Cash FlowLast quarter
$3.3M
$-67.8M
Free Cash FlowOCF − Capex
$3.3M
$-73.0M
FCF MarginFCF / Revenue
44.4%
-537.4%
Capex IntensityCapex / Revenue
0.6%
37.8%
Cash ConversionOCF / Net Profit
1.42×
TTM Free Cash FlowTrailing 4 quarters
$-263.5M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
LSBK
LSBK
NRIX
NRIX
Q4 25
$-67.8M
Q3 25
$3.3M
$-57.4M
Q2 25
$2.5M
$-63.2M
Q1 25
$-61.1M
Q4 24
$-48.8M
Q3 24
$-42.2M
Q2 24
$-39.7M
Q1 24
$-42.0M
Free Cash Flow
LSBK
LSBK
NRIX
NRIX
Q4 25
$-73.0M
Q3 25
$3.3M
$-60.1M
Q2 25
$2.0M
$-65.8M
Q1 25
$-64.6M
Q4 24
$-50.9M
Q3 24
$-44.5M
Q2 24
$-41.6M
Q1 24
$-44.8M
FCF Margin
LSBK
LSBK
NRIX
NRIX
Q4 25
-537.4%
Q3 25
44.4%
-761.3%
Q2 25
28.5%
-149.4%
Q1 25
-349.9%
Q4 24
-382.8%
Q3 24
-353.7%
Q2 24
-344.4%
Q1 24
-270.3%
Capex Intensity
LSBK
LSBK
NRIX
NRIX
Q4 25
37.8%
Q3 25
0.6%
34.3%
Q2 25
7.7%
6.1%
Q1 25
18.9%
Q4 24
15.8%
Q3 24
18.6%
Q2 24
16.0%
Q1 24
17.4%
Cash Conversion
LSBK
LSBK
NRIX
NRIX
Q4 25
Q3 25
1.42×
Q2 25
1.31×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

LSBK
LSBK

Segment breakdown not available.

NRIX
NRIX

Pfizer$11.9M88%
Gilead Agreement$1.7M13%

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