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Side-by-side financial comparison of Lakeside Holding Ltd (LSH) and LEXICON PHARMACEUTICALS, INC. (LXRX). Click either name above to swap in a different company.

Lakeside Holding Ltd is the larger business by last-quarter revenue ($7.0M vs $5.5M, roughly 1.3× LEXICON PHARMACEUTICALS, INC.). Lakeside Holding Ltd runs the higher net margin — -22.6% vs -282.7%, a 260.1% gap on every dollar of revenue. On growth, LEXICON PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (254.4% vs 95.0%).

Lakeside Press was a Chicago publishing imprint under which the RR Donnelley Company produced fine books as well as mail order catalogs, telephone directories, encyclopedias, and advertising. The Press was best known for its high quality editions for the Chicago Caxton Club as well as the Lakeside Classics, a series of fine reprints.

Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its patented mouse gene knockout technology and extensive in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 1...

LSH vs LXRX — Head-to-Head

Bigger by revenue
LSH
LSH
1.3× larger
LSH
$7.0M
$5.5M
LXRX
Growing faster (revenue YoY)
LXRX
LXRX
+159.4% gap
LXRX
254.4%
95.0%
LSH
Higher net margin
LSH
LSH
260.1% more per $
LSH
-22.6%
-282.7%
LXRX

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
LSH
LSH
LXRX
LXRX
Revenue
$7.0M
$5.5M
Net Profit
$-1.6M
$-15.5M
Gross Margin
27.2%
96.3%
Operating Margin
-21.3%
-269.1%
Net Margin
-22.6%
-282.7%
Revenue YoY
95.0%
254.4%
Net Profit YoY
18.7%
54.0%
EPS (diluted)
$-0.08
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
LSH
LSH
LXRX
LXRX
Q4 25
$7.0M
$5.5M
Q3 25
$6.1M
$14.2M
Q2 25
$6.3M
$28.9M
Q1 25
$3.8M
$1.3M
Q4 24
$3.6M
$1.6M
Q3 24
$4.1M
$1.7M
Q2 24
$1.6M
Q1 24
$1.1M
Net Profit
LSH
LSH
LXRX
LXRX
Q4 25
$-1.6M
$-15.5M
Q3 25
$-1.4M
$-12.8M
Q2 25
$-893.1K
$3.3M
Q1 25
$-1.1M
$-25.3M
Q4 24
$-1.9M
Q3 24
$-1.3M
$-64.8M
Q2 24
$-53.4M
Q1 24
$-48.4M
Gross Margin
LSH
LSH
LXRX
LXRX
Q4 25
27.2%
96.3%
Q3 25
18.2%
99.9%
Q2 25
26.7%
99.9%
Q1 25
18.8%
97.6%
Q4 24
-1.2%
77.5%
Q3 24
12.8%
95.9%
Q2 24
89.7%
Q1 24
97.2%
Operating Margin
LSH
LSH
LXRX
LXRX
Q4 25
-21.3%
-269.1%
Q3 25
-20.8%
-85.9%
Q2 25
-8.9%
12.9%
Q1 25
-28.2%
-2034.8%
Q4 24
-55.6%
Q3 24
-32.5%
-3658.4%
Q2 24
-3423.3%
Q1 24
-4147.6%
Net Margin
LSH
LSH
LXRX
LXRX
Q4 25
-22.6%
-282.7%
Q3 25
-22.2%
-90.0%
Q2 25
-14.2%
11.3%
Q1 25
-28.2%
-2004.4%
Q4 24
-54.1%
Q3 24
-32.7%
-3722.6%
Q2 24
-3304.2%
Q1 24
-4427.9%
EPS (diluted)
LSH
LSH
LXRX
LXRX
Q4 25
$-0.08
$-0.04
Q3 25
$-0.09
$-0.04
Q2 25
$-0.11
$0.01
Q1 25
$-0.14
$-0.07
Q4 24
$-0.26
Q3 24
$-0.18
$-0.18
Q2 24
$-0.17
Q1 24
$-0.20

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
LSH
LSH
LXRX
LXRX
Cash + ST InvestmentsLiquidity on hand
$1.6M
$96.2M
Total DebtLower is stronger
$2.4M
Stockholders' EquityBook value
$12.2M
$107.5M
Total Assets
$24.3M
$185.0M
Debt / EquityLower = less leverage
0.20×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
LSH
LSH
LXRX
LXRX
Q4 25
$1.6M
$96.2M
Q3 25
$4.5M
$116.0M
Q2 25
$5.0M
$139.0M
Q1 25
$1.5M
$194.8M
Q4 24
$1.1M
$238.0M
Q3 24
$2.7M
$258.4M
Q2 24
$310.0M
Q1 24
$355.6M
Total Debt
LSH
LSH
LXRX
LXRX
Q4 25
$2.4M
Q3 25
$2.4M
Q2 25
$1.4M
Q1 25
$774.2K
Q4 24
$784.8K
Q3 24
$589.9K
Q2 24
Q1 24
Stockholders' Equity
LSH
LSH
LXRX
LXRX
Q4 25
$12.2M
$107.5M
Q3 25
$7.0M
$120.2M
Q2 25
$2.8M
$129.4M
Q1 25
$749.8K
$123.0M
Q4 24
$1.6M
$145.9M
Q3 24
$3.6M
$178.5M
Q2 24
$240.0M
Q1 24
$288.9M
Total Assets
LSH
LSH
LXRX
LXRX
Q4 25
$24.3M
$185.0M
Q3 25
$18.6M
$205.9M
Q2 25
$14.4M
$225.6M
Q1 25
$9.9M
$297.7M
Q4 24
$9.8M
$298.4M
Q3 24
$10.8M
$321.1M
Q2 24
$373.4M
Q1 24
$417.2M
Debt / Equity
LSH
LSH
LXRX
LXRX
Q4 25
0.20×
Q3 25
0.35×
Q2 25
0.48×
Q1 25
1.03×
Q4 24
0.48×
Q3 24
0.16×
Q2 24
Q1 24

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
LSH
LSH
LXRX
LXRX
Operating Cash FlowLast quarter
$-453.5K
$-17.2M
Free Cash FlowOCF − Capex
FCF MarginFCF / Revenue
Capex IntensityCapex / Revenue
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
LSH
LSH
LXRX
LXRX
Q4 25
$-453.5K
$-17.2M
Q3 25
$-4.0M
$-23.8M
Q2 25
$-483.7K
$17.0M
Q1 25
$-238.3K
$-43.8M
Q4 24
$-530.2K
$-178.8M
Q3 24
$-1.4M
$-53.6M
Q2 24
$-48.5M
Q1 24
$-55.1M
Free Cash Flow
LSH
LSH
LXRX
LXRX
Q4 25
Q3 25
Q2 25
$-497.4K
Q1 25
Q4 24
$-560.5K
$-179.8M
Q3 24
$-1.4M
$-53.9M
Q2 24
$-48.8M
Q1 24
FCF Margin
LSH
LSH
LXRX
LXRX
Q4 25
Q3 25
Q2 25
-7.9%
Q1 25
Q4 24
-15.6%
-11600.7%
Q3 24
-34.5%
-3097.4%
Q2 24
-3017.3%
Q1 24
Capex Intensity
LSH
LSH
LXRX
LXRX
Q4 25
Q3 25
0.0%
Q2 25
0.2%
Q1 25
0.0%
Q4 24
0.8%
66.5%
Q3 24
0.1%
17.6%
Q2 24
15.5%
Q1 24
0.0%
Cash Conversion
LSH
LSH
LXRX
LXRX
Q4 25
Q3 25
Q2 25
5.23×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

LSH
LSH

Transferred Over Time$4.6M65%
Distribution Of Pharmaceutical Products$2.4M35%

LXRX
LXRX

Segment breakdown not available.

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