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Side-by-side financial comparison of LEXICON PHARMACEUTICALS, INC. (LXRX) and SWK Holdings Corp (SWKH). Click either name above to swap in a different company.
SWK Holdings Corp is the larger business by last-quarter revenue ($8.7M vs $5.5M, roughly 1.6× LEXICON PHARMACEUTICALS, INC.). On growth, LEXICON PHARMACEUTICALS, INC. posted the faster year-over-year revenue change (254.4% vs -29.7%). Over the past eight quarters, LEXICON PHARMACEUTICALS, INC.'s revenue compounded faster (124.2% CAGR vs -12.5%).
Lexicon Pharmaceuticals, Inc. is a biopharmaceutical company developing treatments for human disease. The company was founded in 1995 in The Woodlands, Texas under the name Lexicon Genetics, Incorporated by co-founders Professor Allan Bradley, FRS and Professor Bradley's postdoctoral fellow Arthur T Sands. The company has used its patented mouse gene knockout technology and extensive in vivo screening capabilities to study nearly 5,000 genes in its Genome5000 program and has identified over 1...
SWK Holdings Corp is a specialty finance firm focused on the healthcare and life sciences sectors. It provides tailored financing solutions including royalty monetization, structured debt, and asset-backed lending to biotech, pharmaceutical, medical device and diagnostic companies, with its core market centered in North America.
LXRX vs SWKH — Head-to-Head
Income Statement — Q4 FY2025 vs Q4 FY2025
| Metric | | |
|---|---|---|
| Revenue | $5.5M | $8.7M |
| Net Profit | $-15.5M | $-19.4M |
| Gross Margin | 96.3% | — |
| Operating Margin | -269.1% | 9.9% |
| Net Margin | -282.7% | — |
| Revenue YoY | 254.4% | -29.7% |
| Net Profit YoY | 54.0% | -430.2% |
| EPS (diluted) | $-0.04 | $-1.59 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $5.5M | $8.7M | ||
| Q3 25 | $14.2M | $10.9M | ||
| Q2 25 | $28.9M | $10.1M | ||
| Q1 25 | $1.3M | $11.8M | ||
| Q4 24 | $1.6M | $12.4M | ||
| Q3 24 | $1.7M | $10.4M | ||
| Q2 24 | $1.6M | $10.8M | ||
| Q1 24 | $1.1M | $11.4M |
| Q4 25 | $-15.5M | $-19.4M | ||
| Q3 25 | $-12.8M | $8.8M | ||
| Q2 25 | $3.3M | $3.5M | ||
| Q1 25 | $-25.3M | $4.5M | ||
| Q4 24 | — | $5.9M | ||
| Q3 24 | $-64.8M | $3.5M | ||
| Q2 24 | $-53.4M | $3.7M | ||
| Q1 24 | $-48.4M | $468.0K |
| Q4 25 | 96.3% | — | ||
| Q3 25 | 99.9% | — | ||
| Q2 25 | 99.9% | — | ||
| Q1 25 | 97.6% | — | ||
| Q4 24 | 77.5% | — | ||
| Q3 24 | 95.9% | — | ||
| Q2 24 | 89.7% | — | ||
| Q1 24 | 97.2% | — |
| Q4 25 | -269.1% | 9.9% | ||
| Q3 25 | -85.9% | 61.3% | ||
| Q2 25 | 12.9% | 46.1% | ||
| Q1 25 | -2034.8% | 68.6% | ||
| Q4 24 | — | 44.7% | ||
| Q3 24 | -3658.4% | 39.2% | ||
| Q2 24 | -3423.3% | 8.3% | ||
| Q1 24 | -4147.6% | 9.5% |
| Q4 25 | -282.7% | — | ||
| Q3 25 | -90.0% | 80.7% | ||
| Q2 25 | 11.3% | 35.2% | ||
| Q1 25 | -2004.4% | 38.4% | ||
| Q4 24 | — | 47.5% | ||
| Q3 24 | -3722.6% | 33.3% | ||
| Q2 24 | -3304.2% | 33.9% | ||
| Q1 24 | -4427.9% | 4.1% |
| Q4 25 | $-0.04 | $-1.59 | ||
| Q3 25 | $-0.04 | $0.72 | ||
| Q2 25 | $0.01 | $0.29 | ||
| Q1 25 | $-0.07 | $0.37 | ||
| Q4 24 | — | $0.47 | ||
| Q3 24 | $-0.18 | $0.28 | ||
| Q2 24 | $-0.17 | $0.30 | ||
| Q1 24 | $-0.20 | $0.04 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $96.2M | $42.8M |
| Total DebtLower is stronger | — | $33.0M |
| Stockholders' EquityBook value | $107.5M | $235.1M |
| Total Assets | $185.0M | $272.4M |
| Debt / EquityLower = less leverage | — | 0.14× |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $96.2M | $42.8M | ||
| Q3 25 | $116.0M | $10.2M | ||
| Q2 25 | $139.0M | $8.0M | ||
| Q1 25 | $194.8M | $29.8M | ||
| Q4 24 | $238.0M | $5.9M | ||
| Q3 24 | $258.4M | $17.2M | ||
| Q2 24 | $310.0M | $5.5M | ||
| Q1 24 | $355.6M | $5.5M |
| Q4 25 | — | $33.0M | ||
| Q3 25 | — | $33.0M | ||
| Q2 25 | — | $33.0M | ||
| Q1 25 | — | $33.0M | ||
| Q4 24 | — | $33.0M | ||
| Q3 24 | — | $33.0M | ||
| Q2 24 | — | $33.0M | ||
| Q1 24 | — | $33.0M |
| Q4 25 | $107.5M | $235.1M | ||
| Q3 25 | $120.2M | $254.2M | ||
| Q2 25 | $129.4M | $246.5M | ||
| Q1 25 | $123.0M | $292.7M | ||
| Q4 24 | $145.9M | $288.7M | ||
| Q3 24 | $178.5M | $283.4M | ||
| Q2 24 | $240.0M | $282.8M | ||
| Q1 24 | $288.9M | $279.9M |
| Q4 25 | $185.0M | $272.4M | ||
| Q3 25 | $205.9M | $289.4M | ||
| Q2 25 | $225.6M | $285.7M | ||
| Q1 25 | $297.7M | $331.3M | ||
| Q4 24 | $298.4M | $332.2M | ||
| Q3 24 | $321.1M | $321.3M | ||
| Q2 24 | $373.4M | $321.0M | ||
| Q1 24 | $417.2M | $322.0M |
| Q4 25 | — | 0.14× | ||
| Q3 25 | — | 0.13× | ||
| Q2 25 | — | 0.13× | ||
| Q1 25 | — | 0.11× | ||
| Q4 24 | — | 0.11× | ||
| Q3 24 | — | 0.12× | ||
| Q2 24 | — | 0.12× | ||
| Q1 24 | — | 0.12× |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $-17.2M | $27.3M |
| Free Cash FlowOCF − Capex | — | $26.8M |
| FCF MarginFCF / Revenue | — | 308.1% |
| Capex IntensityCapex / Revenue | — | 5.9% |
| Cash ConversionOCF / Net Profit | — | — |
| TTM Free Cash FlowTrailing 4 quarters | — | $43.2M |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $-17.2M | $27.3M | ||
| Q3 25 | $-23.8M | $906.0K | ||
| Q2 25 | $17.0M | $7.8M | ||
| Q1 25 | $-43.8M | $8.3M | ||
| Q4 24 | $-178.8M | $23.0M | ||
| Q3 24 | $-53.6M | $6.3M | ||
| Q2 24 | $-48.5M | $5.4M | ||
| Q1 24 | $-55.1M | $4.4M |
| Q4 25 | — | $26.8M | ||
| Q3 25 | — | $557.0K | ||
| Q2 25 | — | $7.7M | ||
| Q1 25 | — | $8.2M | ||
| Q4 24 | $-179.8M | $22.9M | ||
| Q3 24 | $-53.9M | $6.3M | ||
| Q2 24 | $-48.8M | $5.4M | ||
| Q1 24 | — | — |
| Q4 25 | — | 308.1% | ||
| Q3 25 | — | 5.1% | ||
| Q2 25 | — | 77.0% | ||
| Q1 25 | — | 69.1% | ||
| Q4 24 | -11600.7% | 185.3% | ||
| Q3 24 | -3097.4% | 60.4% | ||
| Q2 24 | -3017.3% | 49.7% | ||
| Q1 24 | — | — |
| Q4 25 | — | 5.9% | ||
| Q3 25 | 0.0% | 3.2% | ||
| Q2 25 | — | 0.6% | ||
| Q1 25 | — | 0.8% | ||
| Q4 24 | 66.5% | 1.1% | ||
| Q3 24 | 17.6% | 0.3% | ||
| Q2 24 | 15.5% | 0.2% | ||
| Q1 24 | 0.0% | 0.0% |
| Q4 25 | — | — | ||
| Q3 25 | — | 0.10× | ||
| Q2 25 | 5.23× | 2.21× | ||
| Q1 25 | — | 1.82× | ||
| Q4 24 | — | 3.93× | ||
| Q3 24 | — | 1.82× | ||
| Q2 24 | — | 1.47× | ||
| Q1 24 | — | 9.47× |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
LXRX
Segment breakdown not available.
SWKH
| Finance Receivables Segment | $8.4M | 96% |
| Other | $329.0K | 4% |
