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Side-by-side financial comparison of MDxHealth SA (MDXH) and Spire Global, Inc. (SPIR). Click either name above to swap in a different company.

MDxHealth SA is the larger business by last-quarter revenue ($19.8M vs $15.8M, roughly 1.3× Spire Global, Inc.).

MDxHealth SA is a global molecular diagnostics company specializing in non-invasive precision oncology tests focused primarily on urological cancers including prostate and bladder cancer. It operates across key markets in North America and Europe, providing clinicians with actionable diagnostic insights to guide personalized treatment decisions, reduce unnecessary invasive procedures, and improve patient care outcomes.

Spire Global, Inc. is a space-to-cloud data and analytics company that specializes in the tracking of global data sets powered by a large constellation of nanosatellites, such as the tracking of maritime, aviation and weather patterns.

MDXH vs SPIR — Head-to-Head

Bigger by revenue
MDXH
MDXH
1.3× larger
MDXH
$19.8M
$15.8M
SPIR

Income Statement — Q1 FY2025 vs Q4 FY2025

Metric
MDXH
MDXH
SPIR
SPIR
Revenue
$19.8M
$15.8M
Net Profit
$-28.0M
Gross Margin
60.8%
40.2%
Operating Margin
-33.3%
-164.1%
Net Margin
-176.6%
Revenue YoY
-26.9%
Net Profit YoY
42.7%
EPS (diluted)
$-0.85

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MDXH
MDXH
SPIR
SPIR
Q4 25
$15.8M
Q3 25
$12.7M
Q2 25
$19.2M
Q1 25
$19.8M
$23.9M
Q4 24
$21.7M
Q3 24
$28.6M
Q2 24
$25.4M
Q1 24
$14.7M
$34.8M
Net Profit
MDXH
MDXH
SPIR
SPIR
Q4 25
$-28.0M
Q3 25
$-19.7M
Q2 25
$119.6M
Q1 25
$-20.7M
Q4 24
$-48.8M
Q3 24
$-12.5M
Q2 24
$-16.6M
Q1 24
$-25.5M
Gross Margin
MDXH
MDXH
SPIR
SPIR
Q4 25
40.2%
Q3 25
36.6%
Q2 25
48.9%
Q1 25
60.8%
36.8%
Q4 24
32.4%
Q3 24
44.5%
Q2 24
43.0%
Q1 24
59.3%
26.5%
Operating Margin
MDXH
MDXH
SPIR
SPIR
Q4 25
-164.1%
Q3 25
-166.1%
Q2 25
-122.7%
Q1 25
-33.3%
-106.5%
Q4 24
-144.1%
Q3 24
-48.0%
Q2 24
-48.6%
Q1 24
-59.3%
-34.4%
Net Margin
MDXH
MDXH
SPIR
SPIR
Q4 25
-176.6%
Q3 25
-155.3%
Q2 25
623.4%
Q1 25
-86.5%
Q4 24
-225.2%
Q3 24
-43.7%
Q2 24
-65.2%
Q1 24
-73.3%
EPS (diluted)
MDXH
MDXH
SPIR
SPIR
Q4 25
$-0.85
Q3 25
$-0.61
Q2 25
$3.72
Q1 25
$-0.77
Q4 24
$-1.93
Q3 24
$-0.50
Q2 24
$-0.68
Q1 24
$-1.17

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MDXH
MDXH
SPIR
SPIR
Cash + ST InvestmentsLiquidity on hand
$81.8M
Total DebtLower is stronger
Stockholders' EquityBook value
$112.9M
Total Assets
$211.0M
Debt / EquityLower = less leverage

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MDXH
MDXH
SPIR
SPIR
Q4 25
$81.8M
Q3 25
$96.8M
Q2 25
$117.6M
Q1 25
$35.9M
Q4 24
$19.2M
Q3 24
$36.6M
Q2 24
$45.8M
Q1 24
$63.7M
Total Debt
MDXH
MDXH
SPIR
SPIR
Q4 25
Q3 25
Q2 25
Q1 25
$103.7M
Q4 24
$103.1M
Q3 24
$4.9M
Q2 24
$4.9M
Q1 24
$123.1M
Stockholders' Equity
MDXH
MDXH
SPIR
SPIR
Q4 25
$112.9M
Q3 25
$133.1M
Q2 25
$149.2M
Q1 25
$3.7M
Q4 24
$-11.7M
Q3 24
$30.8M
Q2 24
$40.3M
Q1 24
$52.5M
Total Assets
MDXH
MDXH
SPIR
SPIR
Q4 25
$211.0M
Q3 25
$224.3M
Q2 25
$239.5M
Q1 25
$208.8M
Q4 24
$193.6M
Q3 24
$224.2M
Q2 24
$230.8M
Q1 24
$252.3M
Debt / Equity
MDXH
MDXH
SPIR
SPIR
Q4 25
Q3 25
Q2 25
Q1 25
27.92×
Q4 24
Q3 24
0.16×
Q2 24
0.12×
Q1 24
2.35×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MDXH
MDXH
SPIR
SPIR
Operating Cash FlowLast quarter
$-4.3M
Free Cash FlowOCF − Capex
$-16.2M
FCF MarginFCF / Revenue
-102.1%
Capex IntensityCapex / Revenue
75.1%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$-92.6M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MDXH
MDXH
SPIR
SPIR
Q4 25
$-4.3M
Q3 25
$-12.0M
Q2 25
$-35.1M
Q1 25
$-8.4M
Q4 24
$-19.2M
Q3 24
$14.0M
Q2 24
$-4.4M
Q1 24
$-8.8M
Free Cash Flow
MDXH
MDXH
SPIR
SPIR
Q4 25
$-16.2M
Q3 25
$-20.4M
Q2 25
$-38.7M
Q1 25
$-17.3M
Q4 24
$-24.3M
Q3 24
$5.1M
Q2 24
$-9.9M
Q1 24
$-15.9M
FCF Margin
MDXH
MDXH
SPIR
SPIR
Q4 25
-102.1%
Q3 25
-161.3%
Q2 25
-201.7%
Q1 25
-72.6%
Q4 24
-112.2%
Q3 24
17.8%
Q2 24
-39.0%
Q1 24
-45.7%
Capex Intensity
MDXH
MDXH
SPIR
SPIR
Q4 25
75.1%
Q3 25
66.2%
Q2 25
18.8%
Q1 25
37.3%
Q4 24
23.5%
Q3 24
31.2%
Q2 24
21.8%
Q1 24
20.3%
Cash Conversion
MDXH
MDXH
SPIR
SPIR
Q4 25
Q3 25
Q2 25
-0.29×
Q1 25
Q4 24
Q3 24
Q2 24
Q1 24

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

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