vs

Side-by-side financial comparison of MEDIFAST INC (MED) and OPKO HEALTH, INC. (OPK). Click either name above to swap in a different company.

OPKO HEALTH, INC. is the larger business by last-quarter revenue ($148.5M vs $75.1M, roughly 2.0× MEDIFAST INC). On growth, OPKO HEALTH, INC. posted the faster year-over-year revenue change (-19.2% vs -36.9%). MEDIFAST INC produced more free cash flow last quarter ($-6.6M vs $-28.6M). Over the past eight quarters, OPKO HEALTH, INC.'s revenue compounded faster (-7.5% CAGR vs -34.4%).

Medifast, Inc. is an American nutrition and weight loss company based in Baltimore, Maryland. Medifast produces, distributes, and sells weight loss and health-related products through websites, multi-level marketing, telemarketing, and franchised weight loss clinics.

OPKO Health, Inc. is a medical test and medication company focused on diagnostics and pharmaceuticals. The company is a publicly traded company on NASDAQ and TASE under the symbol "OPK".

MED vs OPK — Head-to-Head

Bigger by revenue
OPK
OPK
2.0× larger
OPK
$148.5M
$75.1M
MED
Growing faster (revenue YoY)
OPK
OPK
+17.7% gap
OPK
-19.2%
-36.9%
MED
More free cash flow
MED
MED
$22.0M more FCF
MED
$-6.6M
$-28.6M
OPK
Faster 2-yr revenue CAGR
OPK
OPK
Annualised
OPK
-7.5%
-34.4%
MED

Income Statement — Q4 FY2025 vs Q4 FY2025

Metric
MED
MED
OPK
OPK
Revenue
$75.1M
$148.5M
Net Profit
$-31.3M
Gross Margin
69.4%
43.1%
Operating Margin
-10.4%
-25.8%
Net Margin
-21.1%
Revenue YoY
-36.9%
-19.2%
Net Profit YoY
-322.8%
EPS (diluted)
$-1.64
$-0.04

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MED
MED
OPK
OPK
Q4 25
$75.1M
$148.5M
Q3 25
$89.4M
$151.7M
Q2 25
$105.6M
$156.8M
Q1 25
$115.7M
$150.0M
Q4 24
$119.0M
$183.6M
Q3 24
$140.2M
$173.6M
Q2 24
$168.6M
$182.2M
Q1 24
$174.7M
$173.7M
Net Profit
MED
MED
OPK
OPK
Q4 25
$-31.3M
Q3 25
$-2.3M
$21.6M
Q2 25
$2.5M
$-148.4M
Q1 25
$-772.0K
$-67.6M
Q4 24
$14.0M
Q3 24
$1.1M
$24.9M
Q2 24
$-8.2M
$-10.3M
Q1 24
$8.3M
$-81.8M
Gross Margin
MED
MED
OPK
OPK
Q4 25
69.4%
43.1%
Q3 25
69.5%
32.9%
Q2 25
72.6%
31.5%
Q1 25
72.8%
28.4%
Q4 24
74.1%
46.1%
Q3 24
75.4%
23.1%
Q2 24
73.2%
28.4%
Q1 24
72.8%
24.2%
Operating Margin
MED
MED
OPK
OPK
Q4 25
-10.4%
-25.8%
Q3 25
-4.6%
31.7%
Q2 25
-1.0%
-38.3%
Q1 25
-1.1%
-44.8%
Q4 24
0.6%
-18.0%
Q3 24
1.5%
8.2%
Q2 24
-4.7%
-33.9%
Q1 24
4.5%
-41.2%
Net Margin
MED
MED
OPK
OPK
Q4 25
-21.1%
Q3 25
-2.5%
14.3%
Q2 25
2.3%
-94.7%
Q1 25
-0.7%
-45.1%
Q4 24
7.6%
Q3 24
0.8%
14.3%
Q2 24
-4.8%
-5.7%
Q1 24
4.8%
-47.1%
EPS (diluted)
MED
MED
OPK
OPK
Q4 25
$-1.64
$-0.04
Q3 25
$-0.21
$0.03
Q2 25
$0.22
$-0.19
Q1 25
$-0.07
$-0.10
Q4 24
$0.08
$0.02
Q3 24
$0.10
$0.03
Q2 24
$-0.75
$-0.01
Q1 24
$0.76
$-0.12

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MED
MED
OPK
OPK
Cash + ST InvestmentsLiquidity on hand
$167.3M
$364.4M
Total DebtLower is stronger
$344.0M
Stockholders' EquityBook value
$198.9M
$1.3B
Total Assets
$248.0M
$1.9B
Debt / EquityLower = less leverage
0.27×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MED
MED
OPK
OPK
Q4 25
$167.3M
$364.4M
Q3 25
$173.5M
$412.0M
Q2 25
$162.7M
$267.3M
Q1 25
$164.6M
$428.8M
Q4 24
$162.3M
$426.6M
Q3 24
$170.0M
$400.1M
Q2 24
$163.5M
$40.6M
Q1 24
$156.4M
$75.6M
Total Debt
MED
MED
OPK
OPK
Q4 25
$344.0M
Q3 25
$344.2M
Q2 25
$343.3M
Q1 25
$439.2M
Q4 24
$437.2M
Q3 24
$441.0M
Q2 24
$201.9M
Q1 24
$350.1M
Stockholders' Equity
MED
MED
OPK
OPK
Q4 25
$198.9M
$1.3B
Q3 25
$214.7M
$1.3B
Q2 25
$216.0M
$1.3B
Q1 25
$211.0M
$1.3B
Q4 24
$210.1M
$1.4B
Q3 24
$207.3M
$1.4B
Q2 24
$205.3M
$1.4B
Q1 24
$211.0M
$1.3B
Total Assets
MED
MED
OPK
OPK
Q4 25
$248.0M
$1.9B
Q3 25
$268.2M
$2.0B
Q2 25
$269.3M
$2.0B
Q1 25
$280.0M
$2.1B
Q4 24
$284.2M
$2.2B
Q3 24
$291.2M
$2.3B
Q2 24
$293.5M
$2.0B
Q1 24
$302.8M
$2.0B
Debt / Equity
MED
MED
OPK
OPK
Q4 25
0.27×
Q3 25
0.26×
Q2 25
0.26×
Q1 25
0.33×
Q4 24
0.32×
Q3 24
0.31×
Q2 24
0.14×
Q1 24
0.28×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MED
MED
OPK
OPK
Operating Cash FlowLast quarter
$-5.3M
$-25.9M
Free Cash FlowOCF − Capex
$-6.6M
$-28.6M
FCF MarginFCF / Revenue
-8.8%
-19.3%
Capex IntensityCapex / Revenue
1.8%
1.8%
Cash ConversionOCF / Net Profit
TTM Free Cash FlowTrailing 4 quarters
$1.2M
$-190.8M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MED
MED
OPK
OPK
Q4 25
$-5.3M
$-25.9M
Q3 25
$12.1M
$-34.6M
Q2 25
$-3.4M
$-83.4M
Q1 25
$3.4M
$-34.6M
Q4 24
$-4.9M
$-44.4M
Q3 24
$9.1M
$-77.1M
Q2 24
$13.1M
$-26.4M
Q1 24
$7.3M
$-35.6M
Free Cash Flow
MED
MED
OPK
OPK
Q4 25
$-6.6M
$-28.6M
Q3 25
$10.8M
$-37.8M
Q2 25
$-4.8M
$-86.7M
Q1 25
$1.9M
$-37.7M
Q4 24
$-7.2M
$-49.8M
Q3 24
$7.7M
$-85.0M
Q2 24
$11.1M
$-33.7M
Q1 24
$5.4M
$-40.0M
FCF Margin
MED
MED
OPK
OPK
Q4 25
-8.8%
-19.3%
Q3 25
12.0%
-24.9%
Q2 25
-4.5%
-55.3%
Q1 25
1.6%
-25.2%
Q4 24
-6.1%
-27.1%
Q3 24
5.5%
-49.0%
Q2 24
6.6%
-18.5%
Q1 24
3.1%
-23.0%
Capex Intensity
MED
MED
OPK
OPK
Q4 25
1.8%
1.8%
Q3 25
1.5%
2.1%
Q2 25
1.3%
2.1%
Q1 25
1.3%
2.1%
Q4 24
1.9%
2.9%
Q3 24
1.0%
4.6%
Q2 24
1.1%
4.0%
Q1 24
1.1%
2.6%
Cash Conversion
MED
MED
OPK
OPK
Q4 25
Q3 25
-1.60×
Q2 25
-1.36×
Q1 25
Q4 24
-3.17×
Q3 24
8.04×
-3.10×
Q2 24
Q1 24
0.88×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

MED
MED

Segment breakdown not available.

OPK
OPK

Services$71.1M48%
Transfer Of Intellectual Property And Other$33.7M23%
IE$22.1M15%
Rayaldee$8.8M6%
Barda Agreement$6.8M5%
MX$6.3M4%

Related Comparisons