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Side-by-side financial comparison of Medpace Holdings, Inc. (MEDP) and Inotiv, Inc. (NOTV). Click either name above to swap in a different company.

Medpace Holdings, Inc. is the larger business by last-quarter revenue ($708.5M vs $120.9M, roughly 5.9× Inotiv, Inc.). Medpace Holdings, Inc. runs the higher net margin — 19.1% vs -23.5%, a 42.6% gap on every dollar of revenue. On growth, Medpace Holdings, Inc. posted the faster year-over-year revenue change (32.0% vs 0.8%). Medpace Holdings, Inc. produced more free cash flow last quarter ($188.1M vs $-10.6M). Over the past eight quarters, Medpace Holdings, Inc.'s revenue compounded faster (17.7% CAGR vs 0.8%).

Medpace Holdings, Inc. is a global clinical research organization (CRO) based in Cincinnati, Ohio, employing approximately 6,000 people. Operating under a full-service model, the company also offers global central laboratory, imaging core laboratory, and bioanalytical laboratory services, as well as a Phase I unit located on its headquarters and clinical research campus in Cincinnati, Ohio.

Inotiv, Inc. is a contract research organization organized in Indiana and headquartered in Lafayette, Indiana. The company operates two core business units: Discovery and Safety Assessment (DSA) and Research Models and Services (RMS). The CRS business unit offers drug development and environmental sciences services, including safety assessment, analytical, metabolism, CMC and regulatory consultancy for small molecule drug candidates, biotherapeutics, and biomedical devices. The RMS business u...

MEDP vs NOTV — Head-to-Head

Bigger by revenue
MEDP
MEDP
5.9× larger
MEDP
$708.5M
$120.9M
NOTV
Growing faster (revenue YoY)
MEDP
MEDP
+31.2% gap
MEDP
32.0%
0.8%
NOTV
Higher net margin
MEDP
MEDP
42.6% more per $
MEDP
19.1%
-23.5%
NOTV
More free cash flow
MEDP
MEDP
$198.7M more FCF
MEDP
$188.1M
$-10.6M
NOTV
Faster 2-yr revenue CAGR
MEDP
MEDP
Annualised
MEDP
17.7%
0.8%
NOTV

Income Statement — Q4 2025 vs Q1 2026

Metric
MEDP
MEDP
NOTV
NOTV
Revenue
$708.5M
$120.9M
Net Profit
$135.1M
$-28.4M
Gross Margin
Operating Margin
21.6%
-13.5%
Net Margin
19.1%
-23.5%
Revenue YoY
32.0%
0.8%
Net Profit YoY
15.5%
-2.7%
EPS (diluted)
$4.65
$-0.83

Green = leading value per metric. Periods may differ when fiscal calendars don't align.

8-Quarter Revenue & Profit Trend

Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.

Revenue
MEDP
MEDP
NOTV
NOTV
Q4 25
$708.5M
$120.9M
Q3 25
$659.9M
$138.1M
Q2 25
$603.3M
$130.7M
Q1 25
$558.6M
$124.3M
Q4 24
$536.6M
$119.9M
Q3 24
$533.3M
$130.4M
Q2 24
$528.1M
$105.8M
Q1 24
$511.0M
$119.0M
Net Profit
MEDP
MEDP
NOTV
NOTV
Q4 25
$135.1M
$-28.4M
Q3 25
$111.1M
$-8.6M
Q2 25
$90.3M
$-17.6M
Q1 25
$114.6M
$-14.9M
Q4 24
$117.0M
$-27.6M
Q3 24
$96.4M
$-18.9M
Q2 24
$88.4M
$-26.1M
Q1 24
$102.6M
$-48.1M
Operating Margin
MEDP
MEDP
NOTV
NOTV
Q4 25
21.6%
-13.5%
Q3 25
21.5%
-4.9%
Q2 25
20.9%
-4.3%
Q1 25
20.3%
-2.4%
Q4 24
23.4%
-12.9%
Q3 24
21.1%
-10.1%
Q2 24
19.9%
-19.6%
Q1 24
20.4%
-36.2%
Net Margin
MEDP
MEDP
NOTV
NOTV
Q4 25
19.1%
-23.5%
Q3 25
16.8%
-6.2%
Q2 25
15.0%
-13.5%
Q1 25
20.5%
-12.0%
Q4 24
21.8%
-23.0%
Q3 24
18.1%
-14.5%
Q2 24
16.7%
-24.7%
Q1 24
20.1%
-40.4%
EPS (diluted)
MEDP
MEDP
NOTV
NOTV
Q4 25
$4.65
$-0.83
Q3 25
$3.86
$-0.14
Q2 25
$3.10
$-0.51
Q1 25
$3.67
$-0.44
Q4 24
$3.67
$-1.02
Q3 24
$3.01
$-0.73
Q2 24
$2.75
$-1.00
Q1 24
$3.20
$-1.86

Balance Sheet & Financial Strength

Snapshot of each company's liquidity, leverage and book value from the latest quarter.

Metric
MEDP
MEDP
NOTV
NOTV
Cash + ST InvestmentsLiquidity on hand
$497.0M
$12.7M
Total DebtLower is stronger
$405.8M
Stockholders' EquityBook value
$459.1M
$109.0M
Total Assets
$2.0B
$734.3M
Debt / EquityLower = less leverage
3.72×

8-quarter trend — quarters aligned by calendar period.

Cash + ST Investments
MEDP
MEDP
NOTV
NOTV
Q4 25
$497.0M
$12.7M
Q3 25
$285.4M
$21.7M
Q2 25
$46.3M
$6.2M
Q1 25
$441.4M
$19.3M
Q4 24
$669.4M
$38.0M
Q3 24
$656.9M
$21.4M
Q2 24
$510.9M
$14.4M
Q1 24
$407.0M
$32.7M
Total Debt
MEDP
MEDP
NOTV
NOTV
Q4 25
$405.8M
Q3 25
$402.1M
Q2 25
$396.5M
Q1 25
$399.5M
Q4 24
$396.0M
Q3 24
$393.3M
Q2 24
$382.4M
Q1 24
$380.6M
Stockholders' Equity
MEDP
MEDP
NOTV
NOTV
Q4 25
$459.1M
$109.0M
Q3 25
$293.6M
$136.0M
Q2 25
$172.4M
$143.8M
Q1 25
$593.6M
$157.7M
Q4 24
$825.5M
$169.8M
Q3 24
$881.4M
$170.5M
Q2 24
$763.6M
$182.1M
Q1 24
$671.5M
$207.2M
Total Assets
MEDP
MEDP
NOTV
NOTV
Q4 25
$2.0B
$734.3M
Q3 25
$1.8B
$771.1M
Q2 25
$1.6B
$759.7M
Q1 25
$1.9B
$766.0M
Q4 24
$2.1B
$772.9M
Q3 24
$2.1B
$781.4M
Q2 24
$1.9B
$774.6M
Q1 24
$1.8B
$815.4M
Debt / Equity
MEDP
MEDP
NOTV
NOTV
Q4 25
3.72×
Q3 25
2.96×
Q2 25
2.76×
Q1 25
2.53×
Q4 24
2.33×
Q3 24
2.31×
Q2 24
2.10×
Q1 24
1.84×

Cash Flow & Capital Efficiency

How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.

Metric
MEDP
MEDP
NOTV
NOTV
Operating Cash FlowLast quarter
$192.7M
$-5.4M
Free Cash FlowOCF − Capex
$188.1M
$-10.6M
FCF MarginFCF / Revenue
26.6%
-8.8%
Capex IntensityCapex / Revenue
0.6%
4.3%
Cash ConversionOCF / Net Profit
1.43×
TTM Free Cash FlowTrailing 4 quarters
$681.9M
$-28.7M

8-quarter trend — quarters aligned by calendar period.

Operating Cash Flow
MEDP
MEDP
NOTV
NOTV
Q4 25
$192.7M
$-5.4M
Q3 25
$246.2M
$14.3M
Q2 25
$148.5M
$-7.4M
Q1 25
$125.8M
$-12.8M
Q4 24
$190.7M
$-4.5M
Q3 24
$149.1M
$-2.4M
Q2 24
$116.4M
$-14.8M
Q1 24
$152.7M
$16.9M
Free Cash Flow
MEDP
MEDP
NOTV
NOTV
Q4 25
$188.1M
$-10.6M
Q3 25
$235.5M
$11.6M
Q2 25
$142.4M
$-11.5M
Q1 25
$115.8M
$-18.3M
Q4 24
$183.0M
$-9.0M
Q3 24
$138.5M
$-7.7M
Q2 24
$103.5M
$-19.2M
Q1 24
$147.2M
$9.9M
FCF Margin
MEDP
MEDP
NOTV
NOTV
Q4 25
26.6%
-8.8%
Q3 25
35.7%
8.4%
Q2 25
23.6%
-8.8%
Q1 25
20.7%
-14.7%
Q4 24
34.1%
-7.5%
Q3 24
26.0%
-5.9%
Q2 24
19.6%
-18.2%
Q1 24
28.8%
8.3%
Capex Intensity
MEDP
MEDP
NOTV
NOTV
Q4 25
0.6%
4.3%
Q3 25
1.6%
1.9%
Q2 25
1.0%
3.1%
Q1 25
1.8%
4.4%
Q4 24
1.4%
3.7%
Q3 24
2.0%
4.1%
Q2 24
2.4%
4.2%
Q1 24
1.1%
5.9%
Cash Conversion
MEDP
MEDP
NOTV
NOTV
Q4 25
1.43×
Q3 25
2.22×
Q2 25
1.65×
Q1 25
1.10×
Q4 24
1.63×
Q3 24
1.55×
Q2 24
1.32×
Q1 24
1.49×

Financial Flow Comparison

Revenue → gross profit → operating profit → net profit for each company.

Revenue Breakdown by Segment

MEDP
MEDP

Metabolic$249.8M35%
Oncology$195.9M28%
Other$88.3M12%
Central Nervous System$73.2M10%
Cardiology$63.0M9%
Antiviral And Anti Infective$38.3M5%
Related Party$10.3M1%

NOTV
NOTV

Research Models And Services Segment$72.9M60%
Discovery And Safety Assessment Segment$48.0M40%

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