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Side-by-side financial comparison of Medpace Holdings, Inc. (MEDP) and OneMedNet Corp (ONMD). Click either name above to swap in a different company.
Medpace Holdings, Inc. is the larger business by last-quarter revenue ($708.5M vs $890.0K, roughly 796.0× OneMedNet Corp). Medpace Holdings, Inc. runs the higher net margin — 19.1% vs -352.8%, a 371.9% gap on every dollar of revenue. On growth, OneMedNet Corp posted the faster year-over-year revenue change (3323.1% vs 32.0%). Medpace Holdings, Inc. produced more free cash flow last quarter ($188.1M vs $-1.7M). Over the past eight quarters, OneMedNet Corp's revenue compounded faster (89.4% CAGR vs 17.7%).
Medpace Holdings, Inc. is a global clinical research organization (CRO) based in Cincinnati, Ohio, employing approximately 6,000 people. Operating under a full-service model, the company also offers global central laboratory, imaging core laboratory, and bioanalytical laboratory services, as well as a Phase I unit located on its headquarters and clinical research campus in Cincinnati, Ohio.
OneMedNet Corp is a U.S.-headquartered healthcare tech firm offering secure cloud-based data sharing and workflow solutions for medical imaging and patient health information. It serves healthcare providers, insurance payers, and life sciences groups, with its core operating market centered in North America.
MEDP vs ONMD — Head-to-Head
Income Statement — Q4 2025 vs Q4 2025
| Metric | | |
|---|---|---|
| Revenue | $708.5M | $890.0K |
| Net Profit | $135.1M | $-3.1M |
| Gross Margin | — | 20.7% |
| Operating Margin | 21.6% | -353.4% |
| Net Margin | 19.1% | -352.8% |
| Revenue YoY | 32.0% | 3323.1% |
| Net Profit YoY | 15.5% | -32.3% |
| EPS (diluted) | $4.65 | $-0.06 |
Green = leading value per metric. Periods may differ when fiscal calendars don't align.
8-Quarter Revenue & Profit Trend
Side-by-side quarterly history. Quarters aligned by calendar period so offset fiscal years line up.
| Q4 25 | $708.5M | $890.0K | ||
| Q3 25 | $659.9M | $177.0K | ||
| Q2 25 | $603.3M | $155.0K | ||
| Q1 25 | $558.6M | $137.0K | ||
| Q4 24 | $536.6M | $26.0K | ||
| Q3 24 | $533.3M | $142.0K | ||
| Q2 24 | $528.1M | $227.0K | ||
| Q1 24 | $511.0M | $248.0K |
| Q4 25 | $135.1M | $-3.1M | ||
| Q3 25 | $111.1M | $-741.0K | ||
| Q2 25 | $90.3M | $3.0M | ||
| Q1 25 | $114.6M | $-1.9M | ||
| Q4 24 | $117.0M | $-2.4M | ||
| Q3 24 | $96.4M | $-2.1M | ||
| Q2 24 | $88.4M | $-3.6M | ||
| Q1 24 | $102.6M | $-2.1M |
| Q4 25 | — | 20.7% | ||
| Q3 25 | — | -125.4% | ||
| Q2 25 | — | -155.5% | ||
| Q1 25 | — | -163.5% | ||
| Q4 24 | — | -100.0% | ||
| Q3 24 | — | -59.2% | ||
| Q2 24 | — | -44.9% | ||
| Q1 24 | — | -27.8% |
| Q4 25 | 21.6% | -353.4% | ||
| Q3 25 | 21.5% | -1262.7% | ||
| Q2 25 | 20.9% | -1331.0% | ||
| Q1 25 | 20.3% | -1623.4% | ||
| Q4 24 | 23.4% | -10438.5% | ||
| Q3 24 | 21.1% | -1645.1% | ||
| Q2 24 | 19.9% | -1081.1% | ||
| Q1 24 | 20.4% | -847.2% |
| Q4 25 | 19.1% | -352.8% | ||
| Q3 25 | 16.8% | -418.6% | ||
| Q2 25 | 15.0% | 1923.9% | ||
| Q1 25 | 20.5% | -1388.3% | ||
| Q4 24 | 21.8% | -9126.9% | ||
| Q3 24 | 18.1% | -1449.3% | ||
| Q2 24 | 16.7% | -1581.1% | ||
| Q1 24 | 20.1% | -850.4% |
| Q4 25 | $4.65 | $-0.06 | ||
| Q3 25 | $3.86 | $-0.01 | ||
| Q2 25 | $3.10 | $0.07 | ||
| Q1 25 | $3.67 | $-0.06 | ||
| Q4 24 | $3.67 | $-0.07 | ||
| Q3 24 | $3.01 | $-0.07 | ||
| Q2 24 | $2.75 | $-0.14 | ||
| Q1 24 | $3.20 | $-0.08 |
Balance Sheet & Financial Strength
Snapshot of each company's liquidity, leverage and book value from the latest quarter.
| Metric | | |
|---|---|---|
| Cash + ST InvestmentsLiquidity on hand | $497.0M | $585.0K |
| Total DebtLower is stronger | — | $220.0K |
| Stockholders' EquityBook value | $459.1M | $-3.0M |
| Total Assets | $2.0B | $2.2M |
| Debt / EquityLower = less leverage | — | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $497.0M | $585.0K | ||
| Q3 25 | $285.4M | $149.0K | ||
| Q2 25 | $46.3M | $122.0K | ||
| Q1 25 | $441.4M | $144.0K | ||
| Q4 24 | $669.4M | $172.0K | ||
| Q3 24 | $656.9M | $1.9M | ||
| Q2 24 | $510.9M | $407.0K | ||
| Q1 24 | $407.0M | $174.0K |
| Q4 25 | — | $220.0K | ||
| Q3 25 | — | — | ||
| Q2 25 | — | — | ||
| Q1 25 | — | $2.3M | ||
| Q4 24 | — | $2.3M | ||
| Q3 24 | — | $2.3M | ||
| Q2 24 | — | $2.4M | ||
| Q1 24 | — | — |
| Q4 25 | $459.1M | $-3.0M | ||
| Q3 25 | $293.6M | $-3.9M | ||
| Q2 25 | $172.4M | $-3.8M | ||
| Q1 25 | $593.6M | $-16.6M | ||
| Q4 24 | $825.5M | $-15.9M | ||
| Q3 24 | $881.4M | $-14.3M | ||
| Q2 24 | $763.6M | $-19.2M | ||
| Q1 24 | $671.5M | $-15.7M |
| Q4 25 | $2.0B | $2.2M | ||
| Q3 25 | $1.8B | $1.5M | ||
| Q2 25 | $1.6B | $2.3M | ||
| Q1 25 | $1.9B | $1.7M | ||
| Q4 24 | $2.1B | $3.7M | ||
| Q3 24 | $2.1B | $4.4M | ||
| Q2 24 | $1.9B | $1.0M | ||
| Q1 24 | $1.8B | $750.0K |
Cash Flow & Capital Efficiency
How much cash each business actually produces after reinvestment. Cash flow is harder to manipulate than net income.
| Metric | | |
|---|---|---|
| Operating Cash FlowLast quarter | $192.7M | $-1.7M |
| Free Cash FlowOCF − Capex | $188.1M | $-1.7M |
| FCF MarginFCF / Revenue | 26.6% | -193.0% |
| Capex IntensityCapex / Revenue | 0.6% | 0.6% |
| Cash ConversionOCF / Net Profit | 1.43× | — |
| TTM Free Cash FlowTrailing 4 quarters | $681.9M | — |
8-quarter trend — quarters aligned by calendar period.
| Q4 25 | $192.7M | $-1.7M | ||
| Q3 25 | $246.2M | $-1.6M | ||
| Q2 25 | $148.5M | $-2.3M | ||
| Q1 25 | $125.8M | $-1.9M | ||
| Q4 24 | $190.7M | $-2.0M | ||
| Q3 24 | $149.1M | $-1.9M | ||
| Q2 24 | $116.4M | $-1.5M | ||
| Q1 24 | $152.7M | $-1.5M |
| Q4 25 | $188.1M | $-1.7M | ||
| Q3 25 | $235.5M | — | ||
| Q2 25 | $142.4M | $-2.3M | ||
| Q1 25 | $115.8M | $-2.0M | ||
| Q4 24 | $183.0M | $-2.0M | ||
| Q3 24 | $138.5M | $-1.9M | ||
| Q2 24 | $103.5M | $-1.5M | ||
| Q1 24 | $147.2M | $-1.6M |
| Q4 25 | 26.6% | -193.0% | ||
| Q3 25 | 35.7% | — | ||
| Q2 25 | 23.6% | -1475.5% | ||
| Q1 25 | 20.7% | -1425.5% | ||
| Q4 24 | 34.1% | -7811.5% | ||
| Q3 24 | 26.0% | -1346.5% | ||
| Q2 24 | 19.6% | -663.9% | ||
| Q1 24 | 28.8% | -626.2% |
| Q4 25 | 0.6% | 0.6% | ||
| Q3 25 | 1.6% | 0.0% | ||
| Q2 25 | 1.0% | 1.9% | ||
| Q1 25 | 1.8% | 3.6% | ||
| Q4 24 | 1.4% | 134.6% | ||
| Q3 24 | 2.0% | 6.3% | ||
| Q2 24 | 2.4% | 0.4% | ||
| Q1 24 | 1.1% | 2.4% |
| Q4 25 | 1.43× | — | ||
| Q3 25 | 2.22× | — | ||
| Q2 25 | 1.65× | -0.77× | ||
| Q1 25 | 1.10× | — | ||
| Q4 24 | 1.63× | — | ||
| Q3 24 | 1.55× | — | ||
| Q2 24 | 1.32× | — | ||
| Q1 24 | 1.49× | — |
Financial Flow Comparison
Revenue → gross profit → operating profit → net profit for each company.
Revenue Breakdown by Segment
MEDP
| Metabolic | $249.8M | 35% |
| Oncology | $195.9M | 28% |
| Other | $88.3M | 12% |
| Central Nervous System | $73.2M | 10% |
| Cardiology | $63.0M | 9% |
| Antiviral And Anti Infective | $38.3M | 5% |
| Related Party | $10.3M | 1% |
ONMD
Segment breakdown not available.
